Abstract: Provided is a device for transdermal delivery of drugs. The device includes a separable substrate and is loaded with dual drugs based on an interpenetrating polymer network hydrogel. Also provided are methods of making and using the transdermal delivery device.

Abstract: An electronic device and a noise cancelation method thereof are provided. The electronic device includes a driver, a driven device, and an inertial measurement device. The driver is configured to generate a driving signal, and generate a noise prediction signal according to the driving signal. The driven device receives the driving signal to execute an operation, wherein the driven device generates a vibration noise according to generated vibrations when executing the operation. The inertial measurement device is configured to sense a position status of the electronic device to generate sensing information. The inertial measurement device receives the noise prediction signal, and compensates the sensing information according to the noise prediction signal to generate compensated sensing information.

Abstract: A method comprises forming a first fin including alternating first channel layers and first sacrificial layers and a second fin including alternating second channel layers and second sacrificial layers, forming a capping layer over the first and the second fin, forming a dummy gate stack over the capping layer, forming source/drain (S/D) features in the first and the second fin, removing the dummy gate stack to form a gate trench, removing the first sacrificial layers and the capping layer over the first fin to form first gaps, removing the capping layer over the second fin and portions of the second sacrificial layers to from second gaps, where remaining portions of the second sacrificial layers and the capping layers form a threshold voltage (Vt) modulation layer, and forming a metal gate stack in the gate trench, the first gaps, and the second gaps.

Abstract: A computer implemented method for creating a prioritized global conversation thread in a data processing system comprising a processing device and a memory comprising instructions which are executed by the processing device, the method can comprise receiving a plurality of messages from a plurality of message channels; combining a plurality of subsets of the plurality of messages to form a plurality of conversation threads, wherein each subset of the plurality of messages forms one of a plurality of the plurality of conversation threads; extracting a plurality of important messages from the plurality of conversation threads, wherein at least one important message of the plurality of important messages is extracted from each of the plurality of conversation threads; storing the plurality of important messages; determining, for each of the plurality of important messages, a message priority; and displaying, to a user, the plurality of important messages based on the message priority.

Abstract: A computer implemented method for creating a prioritized global conversation thread in a data processing system comprising a processing device and a memory comprising instructions which are executed by the processing device, the method can comprise receiving a plurality of messages from a plurality of message channels; combining a plurality of subsets of the plurality of messages to form a plurality of conversation threads, wherein each subset of the plurality of messages forms one of a plurality of the plurality of conversation threads; extracting a plurality of important messages from the plurality of conversation threads, wherein at least one important message of the plurality of important messages is extracted from each of the plurality of conversation threads; storing the plurality of important messages; determining, for each of the plurality of important messages, a message priority; and displaying, to a user, the plurality of important messages based on the message priority.

Abstract: A sampler circuit for use with a serial communication bus includes an amplifier circuit, an isolation circuit, and a latch circuit. During a first phase, the amplifier circuit amplifies a voltage difference between a first input signal and a second input signal received via the communication bus to generate a voltage difference on output nodes of the latch circuit. During an integration phase, the latch circuit increases the voltage difference on the output nodes. During a regeneration phase, the isolation circuit isolates the amplifier circuit from the latch circuit, which generates full-rail signals based on a voltage difference between the output nodes.

Abstract: Provided is a pharmaceutical composition including gastrodin and a use thereof for the prevention or the treatment of amyotrophic lateral sclerosis. The pharmaceutical composition is effective in reducing neuronal axon degeneration and neurofibromin accumulation, improving symptoms of amyotrophic lateral sclerosis and extending life of patients of amyotrophic lateral sclerosis.

Abstract: Methods, computer program products, and systems are presented. The method computer program products, and systems can include, for instance: obtaining movement path data that specifies a location of a mobile article over time within a geographical area having an infrastructure feature; determining by machine logic based on map data and based on the movement path data calibrated location data of the mobile article, wherein the determining based on map data and based on the movement path data calibrated location data of the mobile article includes using map data that specifies coordinate location data of the infrastructure feature; and providing one or more output based on the determining.

Abstract: Provided is a pharmaceutical composition including gastrodin and a use thereof for the prevention or the treatment of amyotrophic lateral sclerosis. The pharmaceutical composition is effective in reducing neuronal axon degeneration and neurofibromin accumulation, improving symptoms of amyotrophic lateral sclerosis and extending life of patients of amyotrophic lateral sclerosis.

Abstract: An apparatus includes a receiver buffer, a phase compensation circuit, a data sampler circuit, and an error sampler circuit. The receiver buffer may generate an equalized signal on a signal node using an input signal received via a channel. The phase compensation circuit may, in response to an initiation of a training mode, replace the equalized signal on the signal node with a reference signal. The data sampler circuit may sample, using a data clock signal, the reference signal to generate a plurality of data samples. The error sampler circuit may sample, using an error clock signal, the reference signal to generate a plurality of errors samples. The phase compensation circuit may also adjust a phase difference between the data clock signal and the error clock signal using at least some of the plurality of data samples and at least some of the plurality of error samples.

Abstract: Provided is a device for transdermal delivery of drugs. The device includes a separable substrate and is loaded with dual drugs based on an interpenetrating polymer network hydrogel. Also provided are methods of making and using the transdermal delivery device.

Abstract: An apparatus includes a receiver buffer, a phase compensation circuit, a data sampler circuit, and an error sampler circuit. The receiver buffer may generate an equalized signal on a signal node using an input signal received via a channel. The phase compensation circuit may, in response to an initiation of a training mode, replace the equalized signal on the signal node with a reference signal. The data sampler circuit may sample, using a data clock signal, the reference signal to generate a plurality of data samples. The error sampler circuit may sample, using an error clock signal, the reference signal to generate a plurality of errors samples. The phase compensation circuit may also adjust a phase difference between the data clock signal and the error clock signal using at least some of the plurality of data samples and at least some of the plurality of error samples.

Abstract: Methods, computer program products, and systems are presented. The method computer program products, and systems can include, for instance: obtaining movement path data that specifies a location of a mobile article over time within a geographical area having an infrastructure feature; determining by machine logic based on map data and based on the movement path data calibrated location data of the mobile article, wherein the determining based on map data and based on the movement path data calibrated location data of the mobile article includes using map data that specifies coordinate location data of the infrastructure feature; and providing one or more output based on the determining.

Abstract: An apparatus includes a receiver buffer, a phase compensation circuit, a data sampler circuit, and an error sampler circuit. The receiver buffer may generate an equalized signal on a signal node using an input signal received via a channel. The phase compensation circuit may, in response to an initiation of a training mode, replace the equalized signal on the signal node with a reference signal. The data sampler circuit may sample, using a data clock signal, the reference signal to generate a plurality of data samples. The error sampler circuit may sample, using an error clock signal, the reference signal to generate a plurality of errors samples. The phase compensation circuit may also adjust a phase difference between the data clock signal and the error clock signal using at least some of the plurality of data samples and at least some of the plurality of error samples.

Abstract: Methods, computer program products, and systems are presented. The method computer program products, and systems can include, for instance: obtaining movement path data that specifies a location of a mobile article over time within a geographical area having an infrastructure feature; determining by machine logic based on map data and based on the movement path data calibrated location data of the mobile article, wherein the determining based on map data and based on the movement path data calibrated location data of the mobile article includes using map data that specifies coordinate location data of the infrastructure feature; and providing one or more output based on the determining.

Abstract: An apparatus includes a receiver buffer, a phase compensation circuit, a data sampler circuit, and an error sampler circuit. The receiver buffer may generate an equalized signal on a signal node using an input signal received via a channel. The phase compensation circuit may, in response to an initiation of a training mode, replace the equalized signal on the signal node with a reference signal. The data sampler circuit may sample, using a data clock signal, the reference signal to generate a plurality of data samples. The error sampler circuit may sample, using an error clock signal, the reference signal to generate a plurality of errors samples. The phase compensation circuit may also adjust a phase difference between the data clock signal and the error clock signal using at least some of the plurality of data samples and at least some of the plurality of error samples.

Abstract: A method for predicting sudden drop in blood pressure is provided. The method includes following steps: receiving first physiological information corresponding to a first user; receiving a first current blood pressure of the first user; obtaining a sudden drop probability according to a blood feature model, the first physiological information and the first current blood pressure; determining whether the sudden drop probability is not less than a trigger threshold; and determining that a sudden drop in blood pressure will occur in response to determining that the sudden drop probability is not less than the trigger threshold.

Abstract: Methods, computer program products, and systems are presented. The method computer program products, and systems can include, for instance: obtaining movement path data that specifies a location of a mobile article over time within a geographical area having an infrastructure feature; determining by machine logic based on map data and based on the movement path data calibrated location data of the mobile article, wherein the determining based on map data and based on the movement path data calibrated location data of the mobile article includes using map data that specifies coordinate location data of the infrastructure feature; and providing one or more output based on the determining.

Abstract: Techniques are disclosed relating to clock and data recovery circuitry. In some embodiments, a slicing circuit may be configured to sample an input signal to generate a first and second sampled data signal. In some embodiments, a phase detector circuit may be configured to compare the phases of the first and second sampled data signals. In some embodiments, a first charge pump may be configured to supply a first current to a circuit node, and a second charge pump may be configured to supply a second current to the circuit node. In some embodiments, a voltage-controlled oscillator may be configured to adjust a frequency of first and second clock signals based on a voltage of the circuit node.

Abstract: Techniques are disclosed relating to clock and data recovery circuitry. In some embodiments, a slicing circuit may be configured to sample an input signal to generate a first and second sampled data signal. In some embodiments, a phase detector circuit may be configured to compare the phases of the first and second sampled data signals. In some embodiments, a first charge pump may be configured to supply a first current to a circuit node, and a second charge pump may be configured to supply a second current to the circuit node. In some embodiments, a voltage-controlled oscillator may be configured to adjust a frequency of first and second clock signals based on a voltage of the circuit node.