Abstract: A method of preparing an antibody carrying a universal site-directed coupling interface based on a genetically modified vertebrate is described. The method of constructs a vertebrate model, the vertebrate model is used to produce an antibody carrying a universal site-directed coupling interface. The method includes site-directly knocking in a coding gene of a specific recognition sequence of a certain ligase A or a coding gene of a certain intein A at a certain position A of a certain coding gene A of the immunoglobulin in the genome of the recipient animal, to obtain the vertebrate model. The modified mice can normally stimulate immune responses, produce a polyclonal antibody and a monoclonal antibody with a site-directed linking site. Antibodies with a site-directed linking site can normally carry out site-directed linking, and add various application groups to realize downstream applications of antibodies, such as ELISA, immunofluorescence staining, and immuno-PCR.

Abstract: Quinazoline derivatives represented by general formula (1) and quinazoline complexes as protein kinase inhibitors, and their preparation methods are provided. Wherein, in general formula (1), at least one of R and R? is a group containing an atom capable of coordinating with noble metals, m and n are either the same or different and are integers from 0 to 5. Said quinazoline complex as protein kinase inhibitor is formed by coordination compound containing noble metal and said quinazoline derivative ligand capable of coordinating with noble metal in the coordination compound.

Abstract: Quinazoline derivatives represented by general formula (1) and quinazoline complexes as protein kinase inhibitors, and their preparation methods are provided. Wherein, in general formula (1), at least one of R and R? is a group containing an atom capable of coordinating with noble metals, m and n are either the same or different and are integers from 0 to 5. Said quinazoline complex as protein kinase inhibitor is formed by coordination compound containing noble metal and said quinazoline derivative ligand capable of coordinating with noble metal in the coordination compound.

Abstract: A housing of electronic device includes a metallic substrate, a copper layer formed on the metallic substrate, and a heat dissipation layer formed on the copper layer. A method for manufacturing the housing is also provided.

Abstract: A magnesium alloy housing includes a magnesium alloy base, a chemical plating layer, a connecting layer, a hair line layer, and a transparent protecting layer. The chemical plating layer, the connecting layer, the hair line layer, and the transparent protecting layer are formed on the magnesium alloy base in that order.

Abstract: A method of making a magnesium alloy housing includes steps as follows: providing a magnesium alloy base; submerging the magnesium alloy base in a phosphate solution, thereby forming a chemical plating layer on the surface thereof; coating a prime coating on the chemical plating layer and drying the prime coating, thereby forming a prime layer; coating an enamel on the prime layer and drying the enamel, thereby forming a color coating layer; grinding the color coating layer with a grinding wheel, thereby forming a hair line layer; coating a metallic coating on the hair line layer and drying the metallic coating, thereby forming a decorative layer; and coating a transparent coat on the decorative layer and drying the transparent coat, thereby forming a transparent protecting layer.

Abstract: A magnesium alloy housing includes a magnesium alloy base, a chemical plating layer, a connecting layer, a hair line layer, and a transparent protecting layer. The chemical plating layer, the connecting layer, the hair line layer, and the transparent protecting layer are formed on the magnesium alloy base in that order.