Patents by Inventor Shuanglin Xiang

Shuanglin Xiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR BACTERIAL MEDIATED GENE SILENCING AND METHODS OF USING SAME
    Publication number: 20160369282
    Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer of cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
    Type: Application
    Filed: October 6, 2015
    Publication date: December 22, 2016
    Inventors: Chiang Li, Johannes H. Fruehauf, Shuanglin Xiang
  • Compositions for bacterial mediated gene silencing and methods of using same
    Patent number: 9181546
    Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer of cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: November 10, 2015
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Chiang Li, Johannes Fruehauf, Shuanglin Xiang
  • Compositions for Bacterial Mediated Gene Silencing and Methods of Using Same
    Publication number: 20120093773
    Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer of cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
    Type: Application
    Filed: August 2, 2011
    Publication date: April 19, 2012
    Inventors: Chiang Li, Johannes Heinrich Fruehauf, Shuanglin Xiang
  • Compositions for Bacterial Mediated Gene Silencing and Methods of Using the Same
    Publication number: 20090123426
    Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer off cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
    Type: Application
    Filed: December 16, 2005
    Publication date: May 14, 2009
    Inventors: Chiang Li, Johannes Fruehauf, Shuanglin Xiang