Abstract: Disclosed are an SOS1 degrading agent and a preparation method therefor and use thereof. Specifically, disclosed is a compound of formula I: S-L-E(I), wherein L is a linking chain, which links S and E by means of covalent bonds; E is a small molecule ligand of an E3 ubiquitin ligase complex; and S is the structure shown in S7. The compound of formula I of the present invention can degrade and/or inhibit SOS1 protein in cells, and can be used for the treatment and/or prevention of an SOS1-mediated disease or disorder, or a disease or disorder caused by the interaction of SOS1 with Ras or SOS1 with Rac.

Abstract: Disclosed are an SOS1 degrading agent and a preparation method therefor and use thereof. Specifically, disclosed is a compound of formula I: S-L-E (I), wherein L is a linking chain, which links S and E by means of covalent bonds; E is a small molecule ligand of an E3 ubiquitin ligase complex. The compound of formula I of the present invention can degrade and/or inhibit SOS1 protein in cells, and can be used for the treatment and/or prevention of an SOS1-mediated disease or disorder, or a disease or disorder caused by the interaction of SOS1 with Ras or SOS1 with Rac.

Abstract: Embodiments of a method for communicating in a wireless mesh network, a method for communicating in a Bluetooth Low Energy (BLE) mesh network, and a wireless communications device are described. In one embodiment, a method for communicating in a wireless mesh network involves at a first wireless communications device, scanning the wireless mesh network for a unit time period to discover a first transmission time slot within the unit time period that is used by a second wireless communications device in the wireless mesh network, at the first wireless communications device, choosing a second transmission time slot within the unit time period for the first wireless communications device, where the second transmission time slot is different from the first transmission time slot, and from the first wireless communications device, broadcasting data in the wireless mesh network in the second transmission time slot within a subsequent unit time period.

Abstract: Embodiments of a method for communicating in a wireless mesh network, a method for communicating in a Bluetooth Low Energy (BLE) mesh network, and a wireless communications device are described. In one embodiment, a method for communicating in a wireless mesh network involves at a first wireless communications device, scanning the wireless mesh network for a unit time period to discover a first transmission time slot within the unit time period that is used by a second wireless communications device in the wireless mesh network, at the first wireless communications device, choosing a second transmission time slot within the unit time period for the first wireless communications device, where the second transmission time slot is different from the first transmission time slot, and from the first wireless communications device, broadcasting data in the wireless mesh network in the second transmission time slot within a subsequent unit time period.