Patents by Inventor Shuchun GUO

Shuchun GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BENZOHETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND
    Publication number: 20240082406
    Abstract: The present invention provides a benzoheterocycle substituted tetrahydroisoquinoline compound, and in particular, relates to a compound shown in formula (I) and a pharmaceutically acceptable salt thereof, and the compound for the treatment of chronic kidney disease.
    Type: Application
    Filed: December 17, 2021
    Publication date: March 14, 2024
    Inventors: Shuchun GUO, Jun FAN, Nan WU, Zhihua FANG, Wenqiang SHI, Yang LIU, Jianbiao PENG, Haibing GUO
  • FUSED PYRIDONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230227472
    Abstract: Disclosed in the present invention are a fused pyridone compound, and a preparation method therefor and a use thereof. Specifically, the present invention discloses a compound of formula (I-B), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a KRAS inhibitor.
    Type: Application
    Filed: January 25, 2023
    Publication date: July 20, 2023
    Inventors: Shuchun GUO, Jun FAN, Yang LIU, Fang BAO, Jianbiao PENG, Haibing GUO
  • FUSED PYRIDONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220389029
    Abstract: Disclosed in the present invention are a fused pyridone compound, and a preparation method therefor and a use thereof. Specifically, the present invention discloses a compound of formula (I-B), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a KRAS inhibitor.
    Type: Application
    Filed: September 21, 2020
    Publication date: December 8, 2022
    Inventors: Shuchun GUO, Jun FAN, Yang LIU, Fang BAO, Jianbiao PENG, Haibing GUO
  • Tricyclic compound, preparation method therefor and use thereof
    Patent number: 11518766
    Abstract: A compound represented by formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, as well as an application of said compound as an FXIa inhibitor.
    Type: Grant
    Filed: June 28, 2020
    Date of Patent: December 6, 2022
    Assignees: SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD., JIANGXI JEMINCARE GROUP CO., LTD.
    Inventors: Shuchun Guo, Jiangwei Wang, Shan Yao, Yong Zhang, Zhangping Kang, Qiong Zhang, Yan Ye, Jianbiao Peng, Haibing Guo
  • TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220298174
    Abstract: Disclosed are a compound as shown in formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a KRAS inhibitor.
    Type: Application
    Filed: August 3, 2020
    Publication date: September 22, 2022
    Inventors: Shuchun GUO, Jun FAN, Yang LIU, Jianbiao PENG, Haibing GUO
  • HETEROCYCLIC AMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220267364
    Abstract: Disclosed in the present invention are a compound shown in formula (IA), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a STING agonist.
    Type: Application
    Filed: July 24, 2020
    Publication date: August 25, 2022
    Inventors: Jianbiao PENG, Shuchun GUO, Yang LIU, Haibing GUO
  • TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220251095
    Abstract: A compound represented by formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, as well as an application of said compound as an FXIa inhibitor.
    Type: Application
    Filed: June 28, 2020
    Publication date: August 11, 2022
    Inventors: Shuchun GUO, Jiangwei WANG, Shan YAO, Yong ZHANG, Zhangping KANG, Qiong ZHANG, Yan YE, Jianbiao PENG, Haibing GUO
  • Cyclic dinucleotide compound and uses thereof
    Patent number: 11401295
    Abstract: Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.
    Type: Grant
    Filed: October 12, 2019
    Date of Patent: August 2, 2022
    Assignees: SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD., JIANGXI JEMINCARE GROUP CO., LTD.
    Inventors: Shuchun Guo, Jianbiao Peng, Yang Liu, Haibing Guo
  • Aniline-substituted 1,2-dihydropyrrol[3,4-C]pyridin/pyrimidin-3-one derivative and use thereof
    Patent number: 11174254
    Abstract: The present invention relates to a 1,2-dihydropyrrol[3,4-c]pyridin/pyrimidin-3-one derivative substituted by N-(3-aminophenyl)acrylamide and a preparation method and pharmaceutical use thereof. In particular, the present invention relates to a compound of formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof and a preparation method and application of the same. The definition of each substituent in the formula is described in detail in the specification and claims.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: November 16, 2021
    Assignees: YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD., SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD.
    Inventors: Shuchun Guo, Fusheng Zhou, Xiang Chen, Jinzhu Zhao, Dong Huang, Jing Xie, Changjiang Qiao, Wan He, Kai Zhang, Xi Chen, Jiong Lan
  • CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF
    Publication number: 20210340169
    Abstract: Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.
    Type: Application
    Filed: October 12, 2019
    Publication date: November 4, 2021
    Inventors: Shuchun GUO, Jianbiao PENG, Yang LIU, Haibing GUO
  • 4,6,7-trisubstituted 1,2-dihydropyrrolo[3,4-c]pyridin/pyrimidin-3-one derivatives and uses thereof
    Patent number: 11155546
    Abstract: The present disclosure relates to 4,6,7-trisubstituted 1,2-dihydropyrrolo[3,4-c]pyridin/pyrimidin-3-one derivatives, and their preparations and medicinal use. Specifically, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof, wherein the definition of each group is as described in the specification and claims.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: October 26, 2021
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Shuchun Guo, Fusheng Zhou, Xiang Chen, Jinzhu Zhao, Dong Huang, Jing Xie, Changjiang Qiao, Wan He, Kai Zhang, Xi Chen, Jiong Lan
  • 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROLO[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVES AND USES THEREOF
    Publication number: 20200223846
    Abstract: The present disclosure relates to 4,6,7-trisubstituted 1,2-dihydropyrrolo[3,4-c]pyridin/pyrimidin-3-one derivatives, and their preparations and medicinal use. Specifically, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof, wherein the definition of each group is as described in the specification and claims.
    Type: Application
    Filed: March 27, 2020
    Publication date: July 16, 2020
    Inventors: Shuchun GUO, Fusheng ZHOU, Xiang CHEN, Jinzhu ZHAO, Dong HUANG, Jing XIE, Changjiang QIAO, Wan HE, Kai ZHANG, Xi CHEN, Jiong LAN
  • Benzobicycloalkane derivatives, their preparation and pharmaceutical use thereof
    Patent number: 10577346
    Abstract: It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: March 3, 2020
    Assignees: SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD., YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Fusheng Zhou, Shuchun Guo, Jinzhu Zhao, Hui Xu, Xia Shi, Yi Hu, Yufeng Li, Jiong Lan
  • ANILINE-SUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE THEREOF
    Publication number: 20200048248
    Abstract: The present invention relates to a 1,2-dihydropyrrol[3,4-c]pyridin/pyrimidin-3-one derivative substituted by N-(3-aminophenyl)acrylamide and a preparation method and pharmaceutical use thereof. In particular, the present invention relates to a compound of formula (II) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof and a preparation method and application of the same. The definition of each substituent in the formula is described in detail in the specification and claims.
    Type: Application
    Filed: August 3, 2018
    Publication date: February 13, 2020
    Inventors: Shuchun GUO, Fusheng ZHOU, Xiang CHEN, Jinzhu ZHAO, Dong HUANG, Jing XIE, Changjiang QIAO, Wan HE, Kai ZHANG, Xi CHEN, Jiong LAN
  • BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
    Publication number: 20190161468
    Abstract: It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.
    Type: Application
    Filed: November 17, 2017
    Publication date: May 30, 2019
    Inventors: Fusheng ZHOU, Shuchun GUO, Jinzhu ZHAO, Hui XU, Xia SHI, Yi HU, Yufeng LI, Jiong LAN