Abstract: Compositions and methods are provided for simple, instrument-free and sensitive methods that enable rapid, point-of-care detection of nucleic acid molecules of interest. This is based on a surprising discovery that the relative efficiencies of amplification and CRISPR-based cleavage and detection can be tuned to favor amplification until sufficient amplified products are generated to enable detection. Example approaches include design of guide RNA and primers to target nonoptimal PAM sequences, or sequence-engineering Cas nucleases to reduce activities informing a ribonucleoprotein with the guide RNA or binding to or cleaving the substrate nucleic acid.

Abstract: An apparatus includes a light source configured to emit light, a beam shaper configured to project the light to substantially surround the apparatus in a plane and onto an object in the plane, and a receiver configured to project the light reflected from the object in the plane to an image sensor. A distortion parameter of the receiver in conjunction with a difference between the emitted light and the reflected light detected at the image sensor is indicative of at least one of a direction or a distance of the apparatus relative to the object.

Abstract: A ground fault locating method for a power distribution network includes: monitoring each phase line of three phase distribution lines, and in the event of occurrence of waves with fault features, performing wave recording to obtain phase line record files; combining the record files corresponding to each of the three phase lines to obtain fault record files; and synthesizing the fault record files to form a transient record file, determining a fault location according to a wave having a maximum change in wave amplitude between two points in the transient record file, and displaying the fault location in a wiring diagram. The ground fault locating method for a power distribution network can significantly improve accuracy of single-phase ground fault detection.

Abstract: A ground fault locating method for a power distribution network includes: monitoring each phase line of three phase distribution lines, and in the event of occurrence of waves with fault features, performing wave recording to obtain phase line record files; combining the record files corresponding to each of the three phase lines to obtain fault record files; and synthesizing the fault record files to form a transient record file, determining a fault location according to a wave having a maximum change in wave amplitude between two points in the transient record file, and displaying the fault location in a wiring diagram. The ground fault locating method for a power distribution network can significantly improve accuracy of single-phase ground fault detection.

Abstract: An apparatus includes a light source configured to emit light, a beam shaper configured to project the light to substantially surround the apparatus in a plane and onto an object in the plane, and a receiver configured to project the light reflected from the object in the plane to an image sensor. A distortion parameter of the receiver in conjunction with a difference between the emitted light and the reflected light detected at the image sensor is indicative of at least one of a direction or a distance of the apparatus relative to the object.

Abstract: The present invention discloses a system for achieving automatic compensation in glass substrate exposure process, including a measurement machine, a communication interface module and an exposure machine, wherein the measurement machine, for performing measurement on exposed glass substrate, and transmitting measured exposure shift data of each measurement point through communication interface module to a default storage area of exposure machine; and the exposure machine, for reading exposure shift data from each default storage area, obtaining a compensation value corresponding to each measurement point based on the exposure shift data and performing compensation processing on the glass substrate and each exposure point corresponding to each measurement point. The present invention also discloses a corresponding method. The present invention can improve compensation efficiency and accuracy of the exposure machine as save man power.

Abstract: A series summation-calibrating device based on a semi-insulating voltage transformer includes a symmetrical high voltage test power supply, a three-port serial voltage transformer, a semi-insulating voltage transformer and an error measuring apparatus. The present invention is characterized by: a complete set of equipment for measuring the traceability of power frequency voltage ratio can be manufactured; calibrating the line according to the serial addition based on the semi-insulating voltage transformer; measuring the relative error between the three-port serial voltage transformer and the semi-insulating voltage transformer; and mathematically processing the measuring result to obtain the voltage coefficient curve of the semi-insulating voltage transformer error.