Abstract: Novel dithiolane derivatives of formula: ##STR1## wherein X is, a C.sub.2 -C.sub.7 alkylcarbonyl group, benzoyl group, benzoyl group substituted with 1-3 groups selected from halogen, C.sub.1 -C.sub.4 alkyl, and C.sub.1 -C.sub.4 alkoxy; Y represents C.sub.2 -C.sub.7 alkylcarbonyl group, C.sub.2 -C.sub.7 alkoxycarbonyl group or cyano group; and R represents di (C.sub.1 -C.sub.4 alkylamino) group, morpholino group or piperidino group, are produced by reacting glyoxal sodium bisulfite adduct with amine compounds in the presence of acids and then with dithiolates. The dithiolane derivatives can activate liver functions and are effective for treatment and prophylaxis of hepatitis and other hepatic disorders.

Abstract: A cyclohexanedione derivative represented by the general formula (I); ##STR1## wherein R.sup.1, R.sup.4 and R.sup.7 represent independently hydrogen atom or C.sub.1 -C.sub.8 alkyl group, R.sup.2 represents hydrogen atom; C.sub.1 -C.sub.8 alkyl group; C.sub.2 -C.sub.6 alkenyl group; C.sub.3 -C.sub.8 cycloalkyl group; C.sub.2 -C.sub.7 alkoxycarbonyl group; C.sub.1 -C.sub.6 alkylthio C.sub.1 -C.sub.6 alkyl group; a phenyl group; a phenyl group substituted with 1 to 3 groups selected from the group consisting of halogen atom, C.sub.1 -C.sub.6 alkyl group, C.sub.1 -C.sub.6 haloalkyl group, C.sub.1 -C.sub.6 alkoxy group, C.sub.1 -C.sub.6 alkylthio group, C.sub.3 -C.sub.8 cycloalkoxy group, a benzyloxy group and a benzyloxy group substituted with C.sub.1 -C.sub.6 alkoxy group; naphthyl group or a heterocyclic group, R.sup.3 represents hydrogen atom, C.sub.1 -C.sub.8 alkyl group or C.sub.2 -C.sub.7 alkoxycarbonyl group, and R.sup.5 and R.sup.6, which may be the same or different, represent hydrogen atom, C.sub.1 -C.