Patents by Inventor Shuichi Iwadare

Shuichi Iwadare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Threo-adrenalinecarboxylic acid, and the production and uses thereof
    Patent number: 4833268
    Abstract: DL- or L-Threo-3-(3,4-dihydroxyphenyl)-N-methyl-serine which may also be termed as DL- or L-threo-adrenalinecarboxylic acid are now provided, which are new compounds useful for therapeutic treatment of Parkinson's disease and mental depression disease.
    Type: Grant
    Filed: July 30, 1987
    Date of Patent: May 23, 1989
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Toshiharu Nagatsu, Hirotaro Narabayashi, Tomio Takeuchi, Shuichi Iwadare, Ikuo Matsumoto, Junji Yoshizawa, Hajime Morishima, Koji Tomimoto
  • L-aminoacylases
    Patent number: 4745067
    Abstract: L-aminoacylases S.sub.1 and S.sub.2 derived from actinomycetes and having physicochemical characteristics such that it is a L-aminoacylase which acts on a N-acyl-L-amino acid to give a L-amino acid, its substrate profile is wide, and it acts not only on a N-acyl derivative of a natural L-amino acid, but also on a N-acyl derivative of a synthetic L-amino acid, while it does not act on a N-acyl-D-amino acid, a DL-N-acetyl-.alpha.methylbenzylamine and a N-acetyl-D-glucosamine, etc.
    Type: Grant
    Filed: April 29, 1986
    Date of Patent: May 17, 1988
    Assignees: Microbial Chemistry Research Foundation, Banyu Pharmaceutical Co., Ltd.
    Inventors: Hamao Umezawa, Tomio Takeuchi, Toshiharu Nagatsu, Masa Hamada, Shuichi Iwadare, Ikuo Matsumoto, Hajime Morishima
  • Process for microbial production of an optically active 3-(3,4-dihydroxyphenyl)serine
    Patent number: 4699879
    Abstract: N-acyl-DL-3-(3,4-dihydroxyphenyl)serine or a catecholic hydroxyl-protected derivative thereof is stereospecifically de-acylated by reaction with a microorganism of the genus Streptomyces or Streptoverticillium having an acylase or with an extract of said microorganism containing said acylase, to produce L-3-(3,4-dihydroxyphenyl)serine or the hydroxyl-protected derivative thereof, with the N-acyl-D-3-(3,4-dihydroxyphenyl)serine compound remaining unaltered. The L-3-(3,4-dihydroxyphenyl)serine compound so produced can be separated from the N-acyl-D-3-(3,4-dihydroxyphenyl)serine compound owing to the difference in the properties of them.
    Type: Grant
    Filed: November 5, 1984
    Date of Patent: October 13, 1987
    Assignees: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Banyu Pharmaceutical Co.
    Inventors: Hamao Umezawa, Tomio Takeuchi, Toshiharu Nagatsu, Masa Hamada, Shuichi Iwadare, Ikuo Matsumoto, Hajime Morishima