Patents by Inventor Shuichi Miyaura

Shuichi Miyaura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9150902
    Abstract: A novel modified polysaccharide, a solid phase to which the polysaccharide is adhered, methods for detecting N-deacetylase activity, N-sulfotransferase activity and N-deacetylase/N-sulfotransferase activity in a sample which utilizes said solid phase, and detection kits thereof.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: October 6, 2015
    Assignee: SEIKAGAKU CORPORATION
    Inventors: Koji Yamamoto, Kiyoshi Suzuki, Shuichi Miyaura
  • Patent number: 8569001
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: October 29, 2013
    Assignees: Seikagaku Corporation, Saint Louis University
    Inventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
  • Publication number: 20130273048
    Abstract: A stabilizing agent for enhancing stability of a specific-binding-pair-forming substance during storage and a novel blocking agent for preventing non-specific adsorption for use in an assay employing a specific-binding-pair-forming substance. The agent may contain a plant-derived polypeptide as an active ingredient; a blocking agent for preventing non-specific adsorption in an assay employing a specific-binding-pair-forming substance; a composition for use in an assay employing a specific-binding-pair-forming substance, the composition may contain the specific-binding-pair-forming substance and the stabilizing agent or the blocking agent; and a kit for use in an assay employing a specific-binding-pair-forming substance, the kit may contain a stabilizing agent or a blocking agent for preventing non-specific adsorption.
    Type: Application
    Filed: June 11, 2013
    Publication date: October 17, 2013
    Inventors: Takeshi Ishimaru, Shuichi Miyaura
  • Publication number: 20110256563
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Application
    Filed: April 21, 2011
    Publication date: October 20, 2011
    Applicants: Saint Louis University, Seikagaku Corporation
    Inventors: Kazuo OKAMURA, Shuichi Miyaura, Shunji Tomatsu
  • Patent number: 8003337
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: August 23, 2011
    Assignees: Seikagaku Corporation, Saint Louis University
    Inventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
  • Patent number: 7951545
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: May 31, 2011
    Assignees: Seikagaku Corporation, Saint Louis University
    Inventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
  • Publication number: 20090280505
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Application
    Filed: July 20, 2009
    Publication date: November 12, 2009
    Applicants: Seikagaku Corporation, Saint Louis University
    Inventors: Kazuo OKAMURA, Shuichi Miyaura, Shunji Tomatsu
  • Publication number: 20090104627
    Abstract: A novel modified polysaccharide, a solid phase to which the polysaccharide is adhered, methods for detecting N-deacetylase activity, N-sulfotransferase activity and N-deacetylase/N-sulfotransferase activity in a sample which utilizes said solid phase, and detection kits thereof.
    Type: Application
    Filed: June 28, 2006
    Publication date: April 23, 2009
    Applicant: SEIKAGAKU CORPORATION
    Inventors: Koji Yamamoto, Kiyoshi Suzuki, Shuichi Miyaura
  • Patent number: 7468265
    Abstract: The present invention provides a safe and novel stabilizing agent for enzymes; a composition containing an enzyme and the stabilizing agent; and a kit containing the stabilizing agent composition. According to the invention, deactivation or inactivation of the activity of the enzyme during storage, drying, freezing, etc. can be prevented, without raising any problem of potential infection of an enzyme with a pathogen. For purposes of the invention, the stabilizing agent for an enzyme contains a plant-derived polypeptide as an active ingredient.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: December 23, 2008
    Assignee: Seikagaku Corporation
    Inventors: Takeshi Ishimaru, Shuichi Miyaura
  • Publication number: 20050221407
    Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.
    Type: Application
    Filed: April 30, 2003
    Publication date: October 6, 2005
    Inventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
  • Publication number: 20050100935
    Abstract: The invention provides a novel stabilizing agent for enhancing stability of a specific-binding-pair-forming substance during storage and a novel blocking agent for preventing non-specific adsorption for use in an assay employing a specific-binding-pair-forming substance. Specifically, the invention provides a stabilizing agent for a specific-binding-pair-forming substance, the agent containing a plant-derived polypeptide as an active ingredient; a blocking agent for preventing non-specific adsorption in an assay employing a specific-binding-pair-forming substance; a composition for use in an assay employing a specific-binding-pair-forming substance, the composition containing the specific-binding-pair-forming substance and the stabilizing agent or the blocking agent; and a kit for use in an assay employing a specific-binding-pair-forming substance, the kit containing a stabilizing agent or a blocking agent for preventing non-specific adsorption.
    Type: Application
    Filed: August 19, 2004
    Publication date: May 12, 2005
    Inventors: Takeshi Ishimaru, Shuichi Miyaura
  • Publication number: 20050089934
    Abstract: The present invention provides a safe and novel stabilizing agent for enzymes; a composition containing an enzyme and the stabilizing agent; and a kit containing the stabilizing agent composition. According to the invention, deactivation or inactivation of the activity of the enzyme during storage, drying, freezing, etc. can be prevented, without raising any problem of potential infection of an enzyme with a pathogen. For purposes of the invention, the stabilizing agent for an enzyme contains a plant-derived polypeptide as an active ingredient.
    Type: Application
    Filed: August 19, 2004
    Publication date: April 28, 2005
    Inventors: Tsuyoshi Ishimaru, Shuichi Miyaura
  • Patent number: 6150115
    Abstract: The present invention relates to a quantitative determination method for heparan sulfate in body fluid specimens of various chronic diseases, in urine samples of diabetic nephropathy and for diagnosing hepatic diseases and rheumatoid arthritis in blood specimens. And also this method provides a diagnostic tool for judging the condition of diabetic nephropathy, hepatic diseases and rheumatoid arthritis by determination of changes by use of aforementioned quantitative determination of heparan sulfate.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: November 21, 2000
    Assignee: Seikagaku Kogyo Kabushiki Kaisha
    Inventors: Shuichi Miyaura, Sawako Takeshita, Takeshi Ishimaru