Patents by Inventor Shuichi Miyaura
Shuichi Miyaura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9150902Abstract: A novel modified polysaccharide, a solid phase to which the polysaccharide is adhered, methods for detecting N-deacetylase activity, N-sulfotransferase activity and N-deacetylase/N-sulfotransferase activity in a sample which utilizes said solid phase, and detection kits thereof.Type: GrantFiled: June 28, 2006Date of Patent: October 6, 2015Assignee: SEIKAGAKU CORPORATIONInventors: Koji Yamamoto, Kiyoshi Suzuki, Shuichi Miyaura
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Patent number: 8569001Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: GrantFiled: April 21, 2011Date of Patent: October 29, 2013Assignees: Seikagaku Corporation, Saint Louis UniversityInventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
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Publication number: 20130273048Abstract: A stabilizing agent for enhancing stability of a specific-binding-pair-forming substance during storage and a novel blocking agent for preventing non-specific adsorption for use in an assay employing a specific-binding-pair-forming substance. The agent may contain a plant-derived polypeptide as an active ingredient; a blocking agent for preventing non-specific adsorption in an assay employing a specific-binding-pair-forming substance; a composition for use in an assay employing a specific-binding-pair-forming substance, the composition may contain the specific-binding-pair-forming substance and the stabilizing agent or the blocking agent; and a kit for use in an assay employing a specific-binding-pair-forming substance, the kit may contain a stabilizing agent or a blocking agent for preventing non-specific adsorption.Type: ApplicationFiled: June 11, 2013Publication date: October 17, 2013Inventors: Takeshi Ishimaru, Shuichi Miyaura
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Publication number: 20110256563Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: ApplicationFiled: April 21, 2011Publication date: October 20, 2011Applicants: Saint Louis University, Seikagaku CorporationInventors: Kazuo OKAMURA, Shuichi Miyaura, Shunji Tomatsu
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Patent number: 8003337Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: GrantFiled: July 20, 2009Date of Patent: August 23, 2011Assignees: Seikagaku Corporation, Saint Louis UniversityInventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
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Patent number: 7951545Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: GrantFiled: April 30, 2003Date of Patent: May 31, 2011Assignees: Seikagaku Corporation, Saint Louis UniversityInventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
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Publication number: 20090280505Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: ApplicationFiled: July 20, 2009Publication date: November 12, 2009Applicants: Seikagaku Corporation, Saint Louis UniversityInventors: Kazuo OKAMURA, Shuichi Miyaura, Shunji Tomatsu
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Publication number: 20090104627Abstract: A novel modified polysaccharide, a solid phase to which the polysaccharide is adhered, methods for detecting N-deacetylase activity, N-sulfotransferase activity and N-deacetylase/N-sulfotransferase activity in a sample which utilizes said solid phase, and detection kits thereof.Type: ApplicationFiled: June 28, 2006Publication date: April 23, 2009Applicant: SEIKAGAKU CORPORATIONInventors: Koji Yamamoto, Kiyoshi Suzuki, Shuichi Miyaura
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Patent number: 7468265Abstract: The present invention provides a safe and novel stabilizing agent for enzymes; a composition containing an enzyme and the stabilizing agent; and a kit containing the stabilizing agent composition. According to the invention, deactivation or inactivation of the activity of the enzyme during storage, drying, freezing, etc. can be prevented, without raising any problem of potential infection of an enzyme with a pathogen. For purposes of the invention, the stabilizing agent for an enzyme contains a plant-derived polypeptide as an active ingredient.Type: GrantFiled: August 19, 2004Date of Patent: December 23, 2008Assignee: Seikagaku CorporationInventors: Takeshi Ishimaru, Shuichi Miyaura
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Publication number: 20050221407Abstract: A method for detecting lysosomal storage diseases including the steps of performing an assay for a single species of glycosaminoglycan contained in a specimen and correlating results of the assay with lysosomal storage diseases. A body fluid such as urine or blood can be employed as a specimen. The assay can be performed by use of a polypeptide that is capable of specifically binding to a glycosaminoglycan-containing molecule. The polypeptide may be an antibody, or a polypeptide having an antigen-binding site of an antibody.Type: ApplicationFiled: April 30, 2003Publication date: October 6, 2005Inventors: Kazuo Okamura, Shuichi Miyaura, Shunji Tomatsu
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Publication number: 20050100935Abstract: The invention provides a novel stabilizing agent for enhancing stability of a specific-binding-pair-forming substance during storage and a novel blocking agent for preventing non-specific adsorption for use in an assay employing a specific-binding-pair-forming substance. Specifically, the invention provides a stabilizing agent for a specific-binding-pair-forming substance, the agent containing a plant-derived polypeptide as an active ingredient; a blocking agent for preventing non-specific adsorption in an assay employing a specific-binding-pair-forming substance; a composition for use in an assay employing a specific-binding-pair-forming substance, the composition containing the specific-binding-pair-forming substance and the stabilizing agent or the blocking agent; and a kit for use in an assay employing a specific-binding-pair-forming substance, the kit containing a stabilizing agent or a blocking agent for preventing non-specific adsorption.Type: ApplicationFiled: August 19, 2004Publication date: May 12, 2005Inventors: Takeshi Ishimaru, Shuichi Miyaura
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Publication number: 20050089934Abstract: The present invention provides a safe and novel stabilizing agent for enzymes; a composition containing an enzyme and the stabilizing agent; and a kit containing the stabilizing agent composition. According to the invention, deactivation or inactivation of the activity of the enzyme during storage, drying, freezing, etc. can be prevented, without raising any problem of potential infection of an enzyme with a pathogen. For purposes of the invention, the stabilizing agent for an enzyme contains a plant-derived polypeptide as an active ingredient.Type: ApplicationFiled: August 19, 2004Publication date: April 28, 2005Inventors: Tsuyoshi Ishimaru, Shuichi Miyaura
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Patent number: 6150115Abstract: The present invention relates to a quantitative determination method for heparan sulfate in body fluid specimens of various chronic diseases, in urine samples of diabetic nephropathy and for diagnosing hepatic diseases and rheumatoid arthritis in blood specimens. And also this method provides a diagnostic tool for judging the condition of diabetic nephropathy, hepatic diseases and rheumatoid arthritis by determination of changes by use of aforementioned quantitative determination of heparan sulfate.Type: GrantFiled: April 3, 1998Date of Patent: November 21, 2000Assignee: Seikagaku Kogyo Kabushiki KaishaInventors: Shuichi Miyaura, Sawako Takeshita, Takeshi Ishimaru