Patents by Inventor Shuichi Yotsuya

Shuichi Yotsuya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11246309
    Abstract: This invention discloses a preserving agent for organs or tissue comprising (A) quercetin, and (B) at least one sugar selected from the group consisting of fructose and sucrose; a preserving solution for organs or tissue comprising the preserving agent; and a preservation method for organs or tissue comprising the step of immersing an organ or tissue in a liquid mixture comprising (A) quercetin, and (B) at least one sugar selected from the group consisting of fructose and sucrose.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: February 15, 2022
    Assignee: ISHIHARA SANGYO KAISHA, LTD.
    Inventors: Fuminori Kato, Shuichi Yotsuya
  • Publication number: 20180242571
    Abstract: This invention discloses a preserving agent for organs or tissue comprising (A) quercetin, and (B) at least one sugar selected from the group consisting of fructose and sucrose; a preserving solution for organs or tissue comprising the preserving agent; and a preservation method for organs or tissue comprising the step of immersing an organ or tissue in a liquid mixture comprising (A) quercetin, and (B) at least one sugar selected from the group consisting of fructose and sucrose.
    Type: Application
    Filed: August 30, 2016
    Publication date: August 30, 2018
    Applicant: ISHIHARA SANGYO KAISHA, LTD.
    Inventors: Fuminori KATO, Shuichi YOTSUYA
  • Patent number: 8604212
    Abstract: Septic shock is known to lead to, at the end stage, systematic inflammatory reaction syndrome and multiple organ failure (MOF) and cause the patients' death. In both diseases, the patient dies finally of MOF, and the infiltration by inflammatory cells plays a key role for MOF. Thus, development of therapeutic agents for septic shock by suppressing the infiltration by inflammatory cells has been desired. To provide a therapeutic or preventive agent for shock, comprising as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a cycloalkylcarbonyl group, an alkenylcarbonyl group, a thiophenecarbonyl group or a benzoyl group which may be substituted by a halogen atom; and Y is an alkylsulfonyl group.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: December 10, 2013
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shuichi Yotsuya, Hiroshi Shikama
  • Publication number: 20120059039
    Abstract: Septic shock is known to lead to, at the end stage, systematic inflammatory reaction syndrome and multiple organ failure (MOF) and cause the patients' death. In both diseases, the patient dies finally of MOF, and the infiltration by inflammatory cells plays a key role for MOF. Thus, development of therapeutic agents for septic shock by suppressing the infiltration by inflammatory cells has been desired. To provide a therapeutic or preventive agent for shock, comprising as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a cycloalkylcarbonyl group, an alkenylcarbonyl group, a thiophenecarbonyl group or a benzoyl group which may be substituted by a halogen atom; and Y is an alkylsulfonyl group.
    Type: Application
    Filed: May 17, 2010
    Publication date: March 8, 2012
    Applicant: Ishihara Sangyo Kaisha Ltd
    Inventors: Shuichi Yotsuya, Hiroshi Shikama
  • Patent number: 6713500
    Abstract: The present invention provides an agent for controlling animal diseases caused by parasites, which contains, as an active ingredient, an imidazole compound represented by the formula (I): wherein R1 is a cyano group, R2 is an alkyl group which may be substituted, or a phenyl group which may be substituted, R3 is a chlorine atom, and R4 is a dimethylamino group.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: March 30, 2004
    Assignee: Ishihara Sangyo Kaisha Ltd.
    Inventors: Kyuya Morino, Shuichi Yotsuya, Munekazu Ogawa
  • Patent number: 6664279
    Abstract: A therapeutic or preventive agent for liver diseases, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a —CW1R1 group, a —COCOR2 group, a —CW1NHCOR2 group, a —C(═W1)W2R3 group or a —CW1N(R4)R5 group; Y is an alkyl group, a —CW3R6 group, a —COCOR7 group, a —NHCOR7 group, a —C(═W3)W4R8 group, a —(NH)mSO2R9 group, a —(NH)mSO2OR10 group or a —(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1, W2, W3 an
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: December 16, 2003
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shuichi Yotsuya, Kimie Sakai
  • Patent number: 6653333
    Abstract: A digestive system disease therapeutic or preventive agent containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a —CW1R1 group, a —COCOR2 group, a —CW1NHCOR2 group, a —C(═W1)W2R3 group or a —CW1N(R4)R5 group; Y is an alkyl group, a —CW3R6 group, a —COCOR7 group, a —NHCOR7 group, a —C(═W3)W4R8 group, a —(NH)mSO2R9 group, a —(NH)mSO2OR10 group or a —(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an-alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1, W2,
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: November 25, 2003
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shuichi Yotsuya, Hirohiko Kimura, Tadao Bamba
  • Patent number: 6635665
    Abstract: A therapeutic or preventive agent for pulmonary insufficiency, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: wherein X is a —CW1R1 group, a —COCOR2 group, a —CW1NHCOR2 group, a —C(═W1)W2R3 group or a —CW1N(R4)R5 group; Y is an alkyl group, a —CW3R6 group, a —COCOR7 group, a —NHCOR7 group, a —C(═W3)W4R8 group, a —(NH)mSO2R9 group, a —(NH)mSO2OR10 group or a —(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1,
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: October 21, 2003
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Kyuya Morino, Shuichi Yotsuya, Masashi Imamura
  • Publication number: 20030109551
    Abstract: A therapeutic or preventive agent for pulmonary insufficiency, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: 1
    Type: Application
    Filed: July 25, 2002
    Publication date: June 12, 2003
    Inventors: Kyuya Morino, Shuichi Yotsuya, Masashi Imamura
  • Publication number: 20030100586
    Abstract: The present invention provides an agent for controlling animal diseases caused by parasites, which contains, as an active ingredient, an imidazole compound represented by the formula (I): 1
    Type: Application
    Filed: November 7, 2002
    Publication date: May 29, 2003
    Applicant: ISHIHARA SANGYO KAISHA LTD.
    Inventors: Kyuya Morino, Shuichi Yotsuya, Munekazu Ogawa
  • Publication number: 20030027843
    Abstract: A digestive system disease therapeutic or preventive agent containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: 1
    Type: Application
    Filed: July 29, 2002
    Publication date: February 6, 2003
    Inventors: Shuichi Yotsuya, Hirohiko Kimura, Tadao Bamba
  • Publication number: 20030018054
    Abstract: A therapeutic or preventive agent for liver diseases, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: 1
    Type: Application
    Filed: July 29, 2002
    Publication date: January 23, 2003
    Inventors: Shuichi Yotsuya, Kimie Sakai