Patents by Inventor Shuji Takashi

Shuji Takashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for regulating inflammatory mediators and peptides for useful therein
    Patent number: 8563689
    Abstract: The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from the vesicles or granules in the inflammatory cells in a subject with a chronic inflammatory disease. In this regard, the present invention discloses an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. MANS peptide and active fragments thereof are useful in such methods.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: October 22, 2013
    Assignees: North Carolina State University, Biomarck Pharmaceuticals, Ltd.
    Inventors: Shuji Takashi, Indu Parikh, Kenneth B. Adler, Linda D. Martin, Yuehua Li
  • Methods of reducing inflammation and mucus hypersecretion
    Patent number: 8501911
    Abstract: Methods and compounds for decreasing MARCKS-related inflammation and MARCKS-related mucus hypersecretion or decreasing MARCKS-related inflammation in a subject by the administration of a N-terminal myristoylated protein fragment of the N-terminal region of MARCKS protein or a peptide fragment thereof are disclosed.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: August 6, 2013
    Assignees: Biomarck Pharmaceuticals, Ltd, North Carolina State University
    Inventors: Yuehua Li, Linda D. Martin, Kenneth B. Adler, Shuji Takashi, Indu Parikh
  • METHODS OF REDUCING INFLAMMATION AND MUCUS HYPERSECRETION
    Publication number: 20090220581
    Abstract: Methods and compounds for decreasing MARCKS-related inflammation and MARCKS-related mucus hypersecretion or decreasing MARCKS-related inflammation in a subject by the administration of a N-terminal myristoylated protein fragment of the N-terminal region of MARCKS protein or a peptide fragment thereof are disclosed.
    Type: Application
    Filed: August 6, 2007
    Publication date: September 3, 2009
    Inventors: Yuehua LI, Linda D. Martin, Kenneth B. Adler, Shuji Takashi, Indu Parikh
  • Methods for regulating inflammatory mediators and peptides useful therein
    Patent number: 7544772
    Abstract: The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from the vesicles or granules in the inflammatory cells. In this regard, the present invention discloses an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. MANS peptide and active fragments thereof are useful in such methods.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: June 9, 2009
    Assignee: Biomarck Pharmaceuticals, Ltd.
    Inventors: Shuji Takashi, Indu Parikh, Kenneth B. Adler, Linda D. Martin, Yuehua Li
  • Methods for regulating inflammatory mediators and peptides useful therein
    Publication number: 20060217307
    Abstract: The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from the vesicles or granules in the inflammatory cells. In this regard, the present invention discloses an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. MANS peptide and active fragments thereof are useful in such methods.
    Type: Application
    Filed: March 6, 2006
    Publication date: September 28, 2006
    Inventors: Shuji Takashi, Indu Parikh, Kenneth Adler, Linda Martin, Yuehua Li