Patents by Inventor Shujian Wu

Shujian Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metalloprotease highly expressed in the testis, MMP-29
    Patent number: 7285633
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 23, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shujian Wu, Jian Chen, John N. Feder, Liana Lee, Stanley R. Krystek
  • Method of diagnosing testicular tumors using polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Patent number: 7273706
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: September 25, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: John N. Feder, Shujian Wu, Thomas C. Nelson, Liana M. Lee
  • Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunoglobulin folds, BGS2, 3 and 4 and variants thereof
    Publication number: 20070178088
    Abstract: The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: March 21, 2007
    Publication date: August 2, 2007
    Inventors: Shujian Wu, Stanley Krystek, Liana Lee, John Feder, Janet Cheng
  • Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof
    Publication number: 20070172880
    Abstract: The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: March 21, 2007
    Publication date: July 26, 2007
    Inventors: Ning Lee, Jian Chen, John Feder, Shujian Wu, Han Chang, Liana Lee, Michael Blanar, David Bol
  • Polynucleotide encoding a TRP channel family member, TRP-PLIK2
    Patent number: 7223557
    Abstract: The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: May 29, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ning Lee, Jian Chen, John N. Feder, Shujian Wu, Han Chang, Liana M. Le, Michael A. Blanar, David Bol
  • Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
    Patent number: 7223558
    Abstract: The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: May 29, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shujian Wu, Stanley R. Krystek, Liana Lee, John N. Feder, Janet D. Cheng
  • Polynucleotides encoding a human cell surface protein with immunoglobulin folds, BGS-19
    Patent number: 7202056
    Abstract: The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: April 10, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Liana M. Lee, John N. Feder, Shujian Wu, Jian Chen
  • Novel human cell surface protein with immunoglobulin folds, BGS-19
    Publication number: 20070071743
    Abstract: The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: November 17, 2006
    Publication date: March 29, 2007
    Inventors: Liana Lee, John Feder, Shujian Wu, Jian Chen
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Publication number: 20060269544
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: July 31, 2006
    Publication date: November 30, 2006
    Inventors: John Feder, Shujian Wu, Thomas Nelson
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Publication number: 20060246051
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 2, 2006
    Publication date: November 2, 2006
    Inventors: John Feder, Shujian Wu, Thomas Nelson
  • Testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Patent number: 7122358
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: October 17, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John N. Feder, Thomas C. Nelson, Shujian Wu
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Patent number: 7115402
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: October 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John N. Feder, Shujian Wu, Thomas C. Nelson
  • Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
    Publication number: 20060105379
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: December 21, 2005
    Publication date: May 18, 2006
    Inventors: Shujian Wu, Jian Chen, John Feder, Liana Lee, Stanley Krystek
  • Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
    Patent number: 7034134
    Abstract: The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: April 25, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shujian Wu, Jian Chen
  • Polynucleotides encoding a novel human Kupffer cell receptor protein, BGS-18
    Publication number: 20060003367
    Abstract: The present invention provides novel polynucleotides encoding BGS-18 polypeptide, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-18 polypeptide to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: January 5, 2006
    Inventors: Shujian Wu, John Feder, Thomas Nelson
  • Polynucleotides encoding a novel human neuronal cell adhesion protein, BGS-28, and variants thereof
    Publication number: 20050048620
    Abstract: The present invention provides novel polynucleotides encoding BGS-28 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-28 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: August 25, 2004
    Publication date: March 3, 2005
    Inventors: Shujian Wu, John Feder
  • Polynucleotides encoding novel adiponectin receptor variants
    Publication number: 20050032166
    Abstract: The present invention provides novel polynucleotides encoding human AdipoR2v1 polypeptides, mouse AdipoR2v1 polypeptides, human AdipoR3 polypeptides, human AdipoR2v2 polypeptides, human AdipoR3v1 polypeptides, rat AdipoR1 polypeptides, rat AdipoR2 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human AdipoR2v1 polypeptides, mouse AdipoR2v1 polypeptides, human AdipoR3 polypeptides, human AdipoR2v2 polypeptides, human AdipoR3v1 polypeptides, rat AdipoR1 polypeptides, rat AdipoR2 polypeptides, to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: June 23, 2004
    Publication date: February 10, 2005
    Inventors: Jian Chen, Shujian Wu, Ning Lee
  • Polynucleotides encoding novel variants of the TRP channel family member, LTRPC3
    Publication number: 20040229315
    Abstract: The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: May 10, 2004
    Publication date: November 18, 2004
    Inventors: Ning Lee, Jian Chen, John N. Feder, Shujian Wu, Michael A. Blanar, David K. Bol, Paul C. Levesque, Lucy Sun
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Publication number: 20040171131
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: August 7, 2003
    Publication date: September 2, 2004
    Inventors: John N. Feder, Thomas C. Nelson, Shujian Wu, Stanley R. Krystek
  • Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    Publication number: 20040157234
    Abstract: The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: July 9, 2003
    Publication date: August 12, 2004
    Inventors: John N. Feder, Shujian Wu, Thomas C. Nelson