Abstract: A bar soap composition is made from ingredients comprising: at least one cleanser chosen from soap and a first surfactant; and at least one taurate surfactant chosen from a salt of a fatty acid amide of taurine, a salt of a fatty acid amide of N-methyl taurine, and combinations thereof. The taurate surfactant is different than the first surfactant. The composition is in a solid bar form. Other personal care and home care products that include the taurate surfactants are also disclosed.

Abstract: A cleansing bar composition comprising at least one cleanser chosen from soap and surfactant; taurine, in free or salt form; and one or more hydrophobic stabilizing agents. The hydrophobic stabilizing agent prevents the crystallization of taurine on the surface of the cleansing bar. Also methods of making the cleansing bar to inhibit crystallization of taurine in a cleansing bar.

Abstract: Personal care compositions containing active ingredients and an anti-irritant combination of aloe and taurine are disclosed. Methods of preparing the personal care composition and uses of the personal care composition are also disclosed.

Abstract: Described herein, are personal care compositions comprising a surfactant system; an amino acid, e.g. taurine; and a deposition aid comprising a PVM/MA copolymer having a M.W. of from about 30,000 to about 1,000,000, or a vinylimidazolium vinyl pyrrolidone copolymer. Methods of making and using these compositions are also described.

Abstract: Described herein, are personal care compositions comprising taurine in combination with arginine and glycine, and methods for using the compositions to effect reduction of skin irritation and or inflammation, and/or improving barrier repair of the skin.

Abstract: Described herein, are cleansing bar compositions comprising at least one cleanser chosen from soap and surfactant; taurine, in free or salt form; and at least one polymer. Methods of making using the cleansing bar compositions are also described.

Abstract: A cleansing bar composition comprising at least one cleanser chosen from soap and surfactant; taurine, in free or salt form; and one or more hydrophobic stabilizing agents. The hydrophobic stabilizing agent prevents the crystallization of taurine on the surface of the cleansing bar. Also methods of making the cleansing bar to inhibit crystallization of taurine in a cleansing bar.

Abstract: Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.

Abstract: Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.

Abstract: Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.

Abstract: Prodrug formulations of insulin and insulin analogs are provided wherein the insulin peptide has been modified by an amide bond linkage of a dipeptide prodrug element. The prodrugs disclosed herein have extended half lives of at least 10 hours, and more typically greater than 2 hours, 20 hours and less than 70 hours, and are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.

Abstract: Insulin-like growth factor analogs are disclosed wherein substitution of the IGF native amino acids, at positions corresponding to positions B16 and B17 of native insulin, with tyrosine and leucine, respectively, increases potency of the resulting analog at the insulin receptor by tenfold. Also disclosed are prodrug and depot formulations of the IGF analogs, wherein the IGF analog has been modified by the linkage of a dipeptide to the analog through an amide bond linkage. The prodrug and depot formulations disclosed herein have extended half lives of at least 2 hours, 10 hours, and more typically greater than 2 are converted to the active form at physiological conditions through a non-enzymatic reaction driven by chemical instability.