Patents by Inventor Shulin He

Shulin He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9951190
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: April 24, 2018
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau
  • Patent number: 9828474
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: November 28, 2017
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau
  • Publication number: 20150376349
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Application
    Filed: September 11, 2015
    Publication date: December 31, 2015
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau
  • Publication number: 20150322239
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 12, 2015
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau
  • Patent number: 9132209
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: September 15, 2015
    Assignee: Howmedia Osteonics Corp.
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau
  • Patent number: 8439975
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 14, 2013
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Patent number: 8415406
    Abstract: A bone cement has a liquid acrylic monomer component, a powdered acrylic polymer component and yellowish beta-carotene (Pro-vitamin A) mixed into one of the liquid or powdered component and FDC blue No. 2 Lake powder mixed into the powdered component. The beta-carotene and FDC blue adds a greenish (yellow plus blue) color to the combined liquid and powdered component. The yellowish color disappears on setting of the bone cement leaving the cement blue.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: April 9, 2013
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Matthew P. Poggie
  • Patent number: 8303657
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: November 6, 2012
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Patent number: 8241564
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: August 14, 2012
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Publication number: 20120187607
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Application
    Filed: February 17, 2012
    Publication date: July 26, 2012
    Applicant: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Patent number: 8133436
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Grant
    Filed: August 5, 2008
    Date of Patent: March 13, 2012
    Assignee: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Publication number: 20110276143
    Abstract: A method for producing a wear resistant polyethylene medical implant includes forming a medical implant, such as an orthopedic implant, made at least partially of ultra high molecular weight polyethylene (UHMWPE). The polyethylene may be irradiated with gamma ray or e-beam radiation to form free radicals and then crosslinked to eliminate free radicals prior to exposure to oxygen. The so treated bearing surface of the crosslinked polyethylene is then coated with a photoinitiator. Thereafter the bearing material is photocrosslinked with ultra-violet (UV) radiation. The photocrosslinking process can also be applied to non-crosslink UHMWPE.
    Type: Application
    Filed: May 7, 2010
    Publication date: November 10, 2011
    Applicant: HOWMEDICA OSTEONICS CORP.
    Inventors: Shulin He, Zongtao Zhang, Keenan Michael Hanson, Shi-Shen Yau, Daniel E. Lawrynowicz, Aiguo Wang
  • Publication number: 20110224325
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Application
    Filed: May 25, 2011
    Publication date: September 15, 2011
    Applicant: HOWMEDICA OSTEONICS CORP.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang, Daniel E. Lawrynowicz
  • Publication number: 20100036491
    Abstract: A method for manufacturing of ultrahigh molecular weight polyethylene (UHMWPE) for implants, where the implants have been machined out of UHMWPE blocks or extruded rods, has anthocyanin dispersely imbedded in the polyethylene. The implant is then exposed to ? ray or electron beam irradiation in an amount of at least 2.5 Mrad followed by a heat treatment to prevent the implant from becoming brittle in the long term as well as to improve strength and wear. The method includes mixing a powder or granulate resin of UHMWPE with an aqueous liquid that contains anthocyanin in a predetermined amount. The water is then evaporated in order to deposit the anthocyanin in a predetermined concentration on the polyethylene particles. The doped UHMWPE particles are compressed into blocks at temperatures in a range of approximately 135° C.-250° C. and pressures in a range of approximately 2-70 MPa. Medical implants are made from the blocks.
    Type: Application
    Filed: August 5, 2008
    Publication date: February 11, 2010
    Applicant: Howmedica Osteonics Corp.
    Inventors: Shulin He, Shi-Shen Yau, Aiguo Wang
  • Publication number: 20070213425
    Abstract: An acrylic bone cement composition, including a liquid monomer component and a polymer powder component in the form of beads. The liquid monomer component includes a methylmethacrylate polymer and the polymer component includes a polymethylmethacrylate polymer powder, wherein the polymer powder component is subjected to a milling process.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 13, 2007
    Applicant: Howmedica Osteonics Corp.
    Inventors: Paul Higham, Shulin He
  • Publication number: 20070117878
    Abstract: A bone cement has a liquid acrylic monomer component, a powdered acrylic polymer component and yellowish beta-carotene (Pro-vitamin A) mixed into one of the liquid or powdered component and FDC blue No. 2 Lake powder mixed into the powdered component. The beta-carotene and FDC blue adds a greenish (yellow plus blue) color to the combined liquid and powdered component. The yellowish color disappears on setting of the bone cement leaving the cement blue.
    Type: Application
    Filed: January 16, 2007
    Publication date: May 24, 2007
    Inventors: Shulin He, Matthew Poggie
  • Publication number: 20070021526
    Abstract: A bone cement has a liquid acrylic monomer component, a powdered acrylic polymer component and beta-carotene (Pro-vitamin A) mixed into one of the liquid or powdered components. The beta-carotene adds a yellowish color to the combined liquid and powdered component. The color disappears on setting of the bone cement.
    Type: Application
    Filed: July 22, 2005
    Publication date: January 25, 2007
    Applicant: Howmedica Osteonics Corp.
    Inventors: Shulin He, Paul Higham
  • Patent number: 6759485
    Abstract: A network consisting essentially of poly(propylene fumarate) cross linked with diacrylate and a method for making same.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: July 6, 2004
    Assignee: William Marsh Rice University
    Inventors: Shulin He, Michael J. Yaszemski, Antonios G. Mikos
  • Publication number: 20020177668
    Abstract: A network consisting essentially of poly(propylene fumarate) cross linked with diacrylate and a method for making same.
    Type: Application
    Filed: April 22, 2002
    Publication date: November 28, 2002
    Applicant: William Marsh Rice University
    Inventors: Shulin He, Michael J. Yaszemski, Antonios G. Mikos
  • Patent number: 6423790
    Abstract: A network consisting essentially of poly(propylene fumarate) cross linked with diacrylate and a method for making same.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: July 23, 2002
    Assignee: William Marsh Rice University
    Inventors: Shulin He, Michael J. Yaszemski, Antonios G. Mikos