Abstract: The present invention is directed to the identification of prognostic molecular markers of cancer and methods of predicting treatment response of a cancer. The invention further discloses molecular chips useful in predicting whether a cancer will respond to treatment. Preferably, the treatment is radiation therapy. Methods of using and methods of making the molecular chips of the invention are also disclosed.

Abstract: A novel method is provided for delivering nucleic acid molecules to the cells of an organism by pulse voltage delivery. The method involves the combination of formulated nucleic acid molecules with devices for injecting the molecules by pulse voltage or an electrical field. Disclosed are compositions and methods for enhancing the administration to and uptake of nucleic acids in a mammal. The methods disclosed provide an increased transfection and/or gene delivery efficiency by enhancing the uptake of formulated nucleic acid molecules by applying an electrical field which destabilizes the cellular membrane thereby opening pores or passageways which allow extracellular material to be introduced to the cell. Also disclosed are examples which demonstrate that the combination of formulated nucleic acid molecules and pulse voltage injection methods results in immune responses which are superior to those obtained by conventional means of delivery.

Abstract: A novel method is provided for delivering nucleic acid molecules to the cells of an organism by pulse voltage delivery. The method involves the combination of formulated nucleic acid molecules with devices for injecting the molecules by pulse voltage or an electrical field. Disclosed are compositions and methods for enhancing the administration to and uptake of nucleic acids in a mammal. The methods disclosed provide an increased transfection and/or gene delivery efficiency by enhancing the uptake of formulated nucleic acid molecules by applying an electrical field which destabilizes the cellular membrane thereby opening pores or passageways which allow extracellular material to be introduced to the cell. Also disclosed are examples which demonstrate that the combination of formulated nucleic acid molecules and pulse voltage injection methods results in immune responses which are superior to those obtained by conventional means of delivery.

Abstract: A combination apparatus of distribution transformer and switch includes a distribution transformer with three-phase and five-column, wherein the arrangement of the low-voltage winding in WYEo-form, the high voltage winding of each phase is connected in series with a high voltage fuse to constitute respectively one of the three high voltage phase arms, and the arrangement in high voltage side is DELTA form which is formed with one high voltage phase arm as one unit. The apparatus can be used in the system in which the neutral is not connected to the ground, or the neutral is connected to the ground through extinguishing-arc coil or through small resistance, and in the system in which the neutral is connected to the ground directly as well. It is possible that the fault phase does not disturb the normal operation of the other phases.