Patents by Inventor Shuling Guo

Shuling Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF TRANSTHYRETIN EXPRESSION
    Publication number: 20140256797
    Abstract: Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
    Type: Application
    Filed: February 20, 2014
    Publication date: September 11, 2014
    Applicant: ISIS PHARMACEUTICALS, INC.
    Inventors: Brett P. Monia, Susan M. Freier, Andrew M. Siwkowski, Shuling Guo
  • Diagnosis and treatment of disease
    Patent number: 8697860
    Abstract: Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: April 15, 2014
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Brett P. Monia, Susan M. Freier, Andrew M. Siwkowski, Shuling Guo
  • MICROFLUIDIC PLATFORM FOR CELL CULTURE AND ASSAY
    Publication number: 20110129850
    Abstract: A microfluidic chip for at least one of cell culturing and cell assay has a cell culture chamber defined by the microfluidic chip, a first microchannel defined by the microfluidic chip and constructed to provide a fluid path to said cell culture chamber, the microchannel having a pneumatic valve formed therein to permit selective opening and closing of a fluid path to said cell culture chamber, and a second microchannel defined by the microfluidic chip and constructed to provide a fluid path from the cell culture chamber.
    Type: Application
    Filed: December 21, 2007
    Publication date: June 2, 2011
    Applicant: UCLA Office of Intellectual Property
    Inventors: Hsian-Rong Tseng, Tak For Yu, Shuling Guo, Owen N. Witte, Caius Radu, Jenny Shu, Kenichiro Kamei