Patents by Inventor Shun-ichiro Ogata

Shun-ichiro Ogata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody for human hematopoietic glycoproteins and method
    Patent number: 4892828
    Abstract: This invention concerns a new monoclonal antibody (mAb) 4C, recognizing a specific antigen, Leu 200, found in human hematopoietic tissues. The monoclonal antibody precipitates a series of glycoproteins (Leu 200) with a molecular weight range of about 190,000 to 230,000 from both T- and B-cell lines. The series of glycoproteins resolves into four discrete glycoprotein bands, the distribution of which varies according to the cell lines. Bands 3 and 4 predominate in a majority of T-cells whereas band 2 predominates in B cells. Thus, a Leu 200 antigen subset distribution is possible with mAb 4C. Bands 1, 2, 3, 4 have apparent molecular weights of 230K, 215K, 205K, and 190K respectively, with differences in their carbohydrate moieties. nAb 4C is a IgG sub two a,kappa immunoglobulin. 4C has potential use in leukemia, hematopoietic cell differentiation and transplantation diagnoses and therapy.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: January 9, 1990
    Assignee: Sloan-Kettering Institute For Cancer Research
    Inventors: Bo Dupont, Yasuo Morishima, Nancy Collins, Shun-ichiro Ogata, Kenneth O. Lloyd
  • Monoclonal antibody for human hematopoietic glycoproteins and method
    Patent number: 4710457
    Abstract: This invention concerns a new monoclonal antibody (mAb) 4C, recognizing a specific antigen, Leu 200, found in human hematopoietic tissues. The monoclonal antibody precipitates a series of glycoproteins (Leu 200) with a molecular weight range of about 190,000 to 230,000 from both T- and B-cell lines. The series of glycoproteins resolves into four discrete glycoprotein bands, the distribution of which varies according to the cell lines. Bands 3 and 4 predominate in a majority of T-cells whereas band 2 predominates in B cells. Thus, a Leu 200 antigen subset distribution is possible with mAb 4C. Bands 1, 2, 3, 4 have apparent molecular weights of 230K, 215K, 205K, and 190K respectively, with differences in their carbohydrate moieties. mAb 4C is a IgG sub two a, kappa immunoglobulin. 4C has potential use in leukemia, hematopoietic cell differentiation and transplantation diagnoses and therapy.
    Type: Grant
    Filed: June 29, 1983
    Date of Patent: December 1, 1987
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Bo Dupont, Yasuo Morishima, Nancy Collins, Shun-ichiro Ogata, Kenneth O. Lloyd
  • Monoclonal antibodies to cell surface antigens of human renal cancer
    Patent number: 4650756
    Abstract: The preparation and use of monoclonal antibodies to human renal tumor cells is described. The monoclonal antibodies bind to glycoproteins of 160Kd, 120Kd and 115Kd, a glycolipid, a HLA heavy chain, group A blood and group B blood antigens.
    Type: Grant
    Filed: August 31, 1981
    Date of Patent: March 17, 1987
    Assignee: Sloan Kettering Institute for Cancer Research
    Inventors: Lloyd J. Old, Kenneth O. Lloyd, Herbert F. Oettgen, Willet F. Whitmore, Jerzy Szkudlarek, Connie L. Finstad, Donna Morrissey, Shun-ichiro Ogata, Ryuzo Ueda