Patents by Inventor Shun Kayahashi

Shun Kayahashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9918951
    Abstract: The invention provides a method of improving the preservation stability of glutathione in a solid composition containing glutathione and arginine. In particular, glutathione and arginine are made to be coexistent with an organic acid such as citric acid, tartaric acid, ascorbic acid, malic acid, malonic acid, succinic acid, fumaric acid, maleic acid and the like. The amount of the organic acid to coexistent with glutathione and arginine is generally 0.1-2 parts by weight relative to 1 part by weight of arginine.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: March 20, 2018
    Assignee: KYOWA HAKKO BIO CO., LTD.
    Inventors: Yasushi Sakai, Shun Kayahashi
  • Patent number: 8178105
    Abstract: The invention provides a composition containing a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof, wherein the pharmacological activities of the fruit body of Agaricus blazei murill or the extract of the fruit body and the amino acid constituting the omithine cycle or the salt thereof are increased synergistically. Such a composition can contain a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof in 10-100 parts by weight per 1 part by weight of the fruit body or the extract.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: May 15, 2012
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Toshikazu Kamiya, Shun Kayahashi, Akio Shirai
  • Publication number: 20100311837
    Abstract: The invention provides a method of improving the preservation stability of glutathione in a solid composition containing glutathione and arginine. In particular, glutathione and arginine are made to be coexistent with an organic acid such as citric acid, tartaric acid, ascorbic acid, malic acid, malonic acid, succinic acid, fumaric acid, maleic acid and the like. The amount of the organic acid to coexistent with glutathione and arginine is generally 0.1-2 parts by weight relative to 1 part by weight of arginine.
    Type: Application
    Filed: February 5, 2009
    Publication date: December 9, 2010
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Yasushi Sakai, Shun Kayahashi
  • Patent number: 7846902
    Abstract: A composition for oral administration is provided, which includes at least one dipeptide represented by the formula: (wherein X represents alanyl, and Y represents valine, leucine or isoleucine), with an object of providing a composition for oral administration which is excellent in nutrition, pharmacological effect and gustation, or providing a composition for oral administration which is excellent in processing characteristics such as solubility and tableting property.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: December 7, 2010
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Yasushi Sakai, Masao Kimura, Shun Kayahashi, Toshikazu Kamiya, Shin-ichi Hashimoto, Hideo Kawabe
  • Publication number: 20100040715
    Abstract: The invention provides a composition containing a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof, wherein the pharmacological activities of the fruit body of Agaricus blazei murill or the extract of the fruit body and the amino acid constituting the omithine cycle or the salt thereof are increased synergistically. Such a composition can contain a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof in 10-100 parts by weight per 1 part by weight of the fruit body or the extract.
    Type: Application
    Filed: December 14, 2007
    Publication date: February 18, 2010
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Toshikazu Kamiya, Shun Kayahashi, Akio Shirai
  • Publication number: 20080305151
    Abstract: The present invention provides a composition for oral administration, which comprises at least one kind of dipeptide represented by the formula: X-Y (wherein X represents alanyl, glycyl, arginyl, seryl, ?-aspartyl or ?-glutamyl, and Y represents valine, leucine or isoleucine), with an object of providing a composition for oral administration which is excellent in nutrition, pharmacological effect and gustation and comprises at least one kind selected from valine, leucine and isoleucine, or providing a composition for oral administration which is excellent in processing characteristics such as solubility and tableting property and comprises at least one kind selected from valine, leucine and isoleucine.
    Type: Application
    Filed: September 20, 2006
    Publication date: December 11, 2008
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Yasushi Sakai, Masao Kimura, Shun Kayahashi, Toshikazu Kamiya, Shin-ichi Hashimoto, Hideo Kawabe
  • Patent number: 7332522
    Abstract: A liver function protecting or improving agent which comprises a compound represented by the formula (I) {in the formula (I), R1, R2, R3, R4, R5, R6, R7, R8 and R9 may be the same or different, and represent hydrogen, halogen, hydroxy, alkoxy or alkyl; and RA represents the formula (II) [in the formula (II), R10 and R11 may be the same or different, and represent hydrogen or halogen, or R10 and R11 together represent a binding] or the formula (III) [in the formula (III), R12 represents hydrogen, halogen, hydroxy, alkoxy, cyano or alkyl, R13 and R14 may be the same or different, and represent hydrogen or halogen, or R13 and R14 together represent a binding]} or a glycoside thereof or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: February 19, 2008
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Yasushi Sakai, Shun Kayahashi, Erika Hashizume, Ryusuke Nakagiri
  • Publication number: 20040122085
    Abstract: A liver function protecting or improving agent which comprises a compound represented by the formula (I) 1
    Type: Application
    Filed: October 3, 2003
    Publication date: June 24, 2004
    Inventors: Yasushi Sakai, Shun Kayahashi, Erika Hashizume, Ryusuke Nakagiri
  • Publication number: 20020110605
    Abstract: The present invention provides a liver function protecting or improving agent, foods and drinks or feeds having liver function protecting or improving activity, and additives for foods and drinks or feeds having liver function protecting or improving activity, which comprise a plant of the family Saxifragaceae or an extract of the plant. Also provided is a method of screening for liver function protecting or improving agents.
    Type: Application
    Filed: December 10, 2001
    Publication date: August 15, 2002
    Inventors: Ryusuke Nakagiri, Toshikazu Kamiya, Erika Hashizume, Yasushi Sakai, Shun Kayahashi