Patents by Inventor Shun-Qing Liang

Shun-Qing Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRIME EDITOR SYSTEM FOR IN VIVO GENOME EDITING
    Publication number: 20230374476
    Abstract: The present applications discloses an NLS-optimized SpCas9-based prime editor that improves genome editing efficiency exemplified by endogenous loci in cultured cell lines. Using this genome modification system, tumor formation can be initiated through somatic cell editing in the adult mouse. Furthermore, a dual adeno-associated vims (AAVs) is utilized for the delivery of a split-intein prime editor for correction of in vivo pathogenic mutations.
    Type: Application
    Filed: February 4, 2022
    Publication date: November 23, 2023
    Inventors: Shun-Qing Liang, Pengpeng Liu, Wen Xue, Scot Wolfe