Abstract: A substance detection system and a substance detection method are provided. The temperature identifying portion identifies a surface temperature of the quartz substrate, based on a difference between a deviation of the fundamental wave frequency from at least any predetermined reference fundamental wave frequency of the reference crystal resonator and the detecting crystal resonator and a deviation of the third harmonic frequency from a predetermined reference third harmonic frequency. The substance identifying portion identifies a temperature at which a contaminant attached to the detecting crystal resonator is desorbed from the detecting crystal resonator to identify the contaminant based on the temperature at which the contaminant is desorbed.

Abstract: To provide a temperature detector without possibility of interruption in temperature detection in detecting a temperature based on a change in oscillation frequency of a crystal element. First and second vibrating regions are formed on a crystal element, the first or the second vibrating region is oscillated with a third harmonic or a fundamental wave by switching switches. A data processing portion obtains frequency change rates of the third harmonic and the fundamental wave in the first vibrating region, and detects the temperature from a difference between them. Further, whether the oscillation of the first vibrating region is abnormal is monitored based on the measurement result of the frequency of the first vibrating region, and when the abnormality is determined, the temperature is detected from similar difference using the second vibrating region.

Abstract: A sensing sensor includes a main body portion, a piezoelectric resonator, a connecting terminal, and an information storage. The main body portion includes a supply region to which the sample solution is supplied. The piezoelectric resonator is disposed to face the supply region and includes a capturing layer that captures a sensing object. The connecting terminal is configured to attachably/detachably connect a conductive path connected to an electrode of the piezoelectric resonator to a frequency measuring unit. The information storage stores calibration curve information to specify a calibration curve that indicates a relationship between a density of the sensing object and a frequency variation amount of the piezoelectric resonator before and after supplying the sample solution.

Abstract: A substance detection system and a substance detection method are provided. The temperature identifying portion identifies a surface temperature of the quartz substrate, based on a difference between a deviation of the fundamental wave frequency from at least any predetermined reference fundamental wave frequency of the reference crystal resonator and the detecting crystal resonator and a deviation of the third harmonic frequency from a predetermined reference third harmonic frequency. The substance identifying portion identifies a temperature at which a contaminant attached to the detecting crystal resonator is desorbed from the detecting crystal resonator to identify the contaminant based on the temperature at which the contaminant is desorbed.

Abstract: A sensing sensor includes a first vibrating region, a second vibrating region, an adsorbing film, a blocking layer, a wiring board, a channel forming member arranged to cover a region of the one surface side of the wiring board to form a channel. The adsorbing film is arranged such that the adsorbing film is located in a region including the central portion in the front-rear direction of the one vibrating region. Assuming that the front end portion of the vibrating region is P1, the front end portion of the adsorbing film is P2, and the central portion of the vibrating region is C, the front end portion of the adsorbing film P2 satisfies a relational expression expressed as follows: (a distance from C to P1)×0.4?(a distance from P1 to P2)?(a distance from C to P1)×0.8.

Abstract: A sensing sensor includes a main body portion, a piezoelectric resonator, a connecting terminal, and an information storage. The main body portion includes a supply region to which the sample solution is supplied. The piezoelectric resonator is disposed to face the supply region and includes a capturing layer that captures a sensing object. The connecting terminal is configured to attachably/detachably connect a conductive path connected to an electrode of the piezoelectric resonator to a frequency measuring unit. The information storage stores calibration curve information to specify a calibration curve that indicates a relationship between a density of the sensing object and a frequency variation amount of the piezoelectric resonator before and after supplying the sample solution.

Abstract: A sensing device is provided that has satisfactory sensing accuracy when a crystal unit where an excitation electrode is formed on both upper and lower surfaces of a piezoelectric piece is used to sense a sensing object. Adsorption regions are arranged in two places so as to intersect a direction of flow of a fluid, thus each of the adsorption regions senses the sensing object and reference regions are individually provided in these adsorption regions. A difference ?f1 between the oscillation frequencies of the regions and a difference ?f2 between the oscillation frequencies of the regions are added, and based on the result of the addition, whether the sensing object is present or not and its concentration are detected.

Abstract: A sensing sensor includes a first vibrating region, a second vibrating region, an adsorbing film, a blocking layer, a wiring board, a channel forming member arranged to cover a region of the one surface side of the wiring board to form a channel. The adsorbing film is arranged such that the adsorbing film is located in a region including the central portion in the front-rear direction of the one vibrating region. Assuming that the front end portion of the vibrating region is P1, the front end portion of the adsorbing film is P2, and the central portion of the vibrating region is C, the front end portion of the adsorbing film P2 satisfies a relational expression expressed as follows: (a distance from C to P1)×0.4?(a distance from P1 to P2)?(a distance from C to P1)×0.8.

Abstract: A sensing device is to be connected to a piezoelectric resonator for sensing a target substance in a sample fluid based on oscillation frequency of the piezoelectric resonator. The sensing device includes an oscillator circuit, a voltage supply unit, an information obtaining unit, and a voltage adjusting unit. The oscillator circuit is commonalized for a plurality kinds of piezoelectric resonators. The voltage supply unit is configured to supply a DC drive voltage to the oscillator circuit. The information obtaining unit is configured to obtain type information of a piezoelectric resonator which is connected to the oscillator circuit. The voltage adjusting unit is configured to adjust the DC drive voltage to a voltage corresponding to the connected piezoelectric resonator based on the type information obtained by the information obtaining unit.

Abstract: It is possible to determine the presence of bacteria in a sample solution in a shorter period of time without changing a conventional incubating method. Bacteria in a sample solution are incubated in, for example, a sterilized agar medium 10 having a layer thickness of 0.1 ?m to 1 ?m formed on an electrode of a crystal resonator 2, and an oscillation frequency is measured. When the bacteria proliferate, the mass of the entire crystal resonator 2 increases, and the oscillation frequency decreases. Therefore, by monitoring presence of such a change over time, presence of bacteria in the sample solution can be determined quickly.

Abstract: To provide a sensing device that holds a piezoelectric sensor and a channel forming member placed on the sensor in a closely contacted state while maintaining a shape of space of a passage space formed inside the device. In a sensing device 1100 that senses a substance to be sensed based on a variation in an oscillation frequency caused by an absorption of the substance to be sensed in an absorption layer provided on a piezoelectric resonator 1720 of a piezoelectric sensor 1700, a holding member 1600 holds the piezoelectric sensor 1700 and a channel forming member 1730 that forms a passage space through which a sample fluid passes on an upper surface side of the sensor, in a vertically stacked state. A cover member 1510 is placed on the channel forming member 1730, and a pressing part 1350 which is raised/lowered by a first raising/lowering mechanism 1300 presses the cover member 1510 placed on the channel forming member 1730 downward with a previously set force.

Abstract: A sensing device is provided that has satisfactory sensing accuracy when a crystal unit where an excitation electrode is formed on both upper and lower surfaces of a piezoelectric piece is used to sense a sensing object. Adsorption regions are arranged in two places so as to intersect a direction of flow of a fluid, thus each of the adsorption regions senses the sensing object and reference regions are individually provided in these adsorption regions. A difference ?f1 between the oscillation frequencies of the regions and a difference ?f2 between the oscillation frequencies of the regions are added, and based on the result of the addition, whether the sensing object is present or not and its concentration are detected.

Abstract: A sensing sensor includes a crystal element having a first excitation electrode, a second excitation electrode, and a common electrode, an adsorbing layer, a wiring board, and a channel forming member. The crystal element is secured to the wiring board so as to form a space at one surface side of the first vibrating region and the second vibrating region. The channel forming member is disposed to form a supply channel of sample solution upward of each of the first vibrating region and the second vibrating region. The channel forming member is disposed such that an inferior surface of a left edge and a right edge of the channel forming member is positioned on the common electrode. The channel forming member is formed such that an injection port of the sample solution and a discharge port of the sample solution are opposed to the crystal element.

Abstract: It is possible to determine the presence of bacteria in a sample solution in a shorter period of time without changing a conventional incubating method. Bacteria in a sample solution are incubated in, for example, a sterilized agar medium 10 having a layer thickness of 0.1 ?m to 1 ?m formed on an electrode of a crystal resonator 2, and an oscillation frequency is measured. When the bacteria proliferate, the mass of the entire crystal resonator 2 increases, and the oscillation frequency decreases. Therefore, by monitoring presence of such a change over time, presence of bacteria in the sample solution can be determined quickly.

Abstract: To provide a sensing device having a high processing power and capable of high-accuracy measurement. It is determined whether or not an oscillation frequency is stabilized while a buffer solution is supplied to a quartz-crystal resonator 4. from a syringe pump 10. When it is determined that the frequency is stabilized, a second valve 14. is switched to a sample solution supply mode to supply a sample solution in an injection loop 14a. to the quartz-crystal resonator 4. An instant at which the sample solution reaches the quartz-crystal resonator 4. and an instant at which the sample solution finishes passing through the quartz-crystal resonator 4. are automatically found based on a supply flow rate of the buffer solution, a volume of the injection loop 14a, a volume of a supply channel supplying the sample solution to the quartz-crystal resonator 4, and an instant at which the second valve 14. is switched to the sample solution supply mode.

Abstract: A sensing method includes supplying the sample solution to the adsorbing layer; subsequently supplying a first liquid to the adsorbing layer, the first liquid including a first sensitizer to bind with the object; subsequently discharging the first liquid from the adsorbing layer; subsequently supplying a second liquid to the adsorbing layer, the second liquid including a second sensitizer, the second sensitizer reacting to the first sensitizer to generate an insoluble material; obtaining a first frequency signal corresponding to an oscillation frequency of the oscillator circuit, the oscillation frequency being obtained by oscillating the piezoelectric resonator after liquid is supplied to the adsorbing layer and before the second liquid is supplied to the adsorbing layer; and obtaining a second frequency signal corresponding to an oscillation frequency of an oscillator circuit, the oscillation frequency being obtained by oscillating the piezoelectric resonator after the second liquid is supplied to the adsor

Abstract: To provide a sensing device and a sensing method that, by a simple method of liquid supply to first and second excitation electrodes, makes it possible to make a first oscillation area adsorb an adsorption substance that adsorbs a substance to be sensed in a sample solution and a blocking substance that prevents the adsorption of a substance and to make the electrode in a second oscillation area adsorb the blocking substance. By the supply of a solution containing the adsorption substance to a first liquid storage space 53A surrounding a first excitation electrode 42A, a front surface of the excitation electrode 42A is made to adsorb the adsorption substance, and next, by the supply of a solution containing the blocking substance to the first liquid storage space 53A, an area, of the excitation electrode 42A, on which the adsorption substance is not adsorbed, is made to adsorb the blocking substance.

Abstract: To provide a sensing device capable of easily sensing a substance to be sensed with high accuracy. When sensing, by supplying a sample solution to an absorption layer 46 while oscillating a quartz-crystal resonator 4 to make the absorption layer absorb a substance to be sensed in the sample solution, the substance to be sensed based on an amount of variation in an oscillation frequency of the quartz-crystal resonator 4 after an absorption time elapses, the quartz-crystal resonator 4 is oscillated, before supplying the sample solution to the absorption layer 46, to measure the oscillation frequency of the quartz-crystal resonator 4 at a predetermined measurement interval, for instance, at every one second, and the oscillation frequency of the quartz-crystal resonator 4 is stabilized for the same period of time as a measuring time 19 until the measurement result becomes equal to or less than a frequency tolerance value 19b previously set based on a measurement sensitivity of the substance to be sensed.

Abstract: A sensing device is configured that a first piezoelectric vibrator and a second piezoelectric vibrator, changing over a connection to an oscillation circuit, have the oscillation circuit in common, that an impedance of a conductive path including a first one-surface-side electrode constituting the first piezoelectric vibrator from the oscillation circuit and an impedance of a conductive path including a second one-surface-side electrode constituting the second piezoelectric vibrator from the oscillation circuit are uniform with each other, and that an impedance of a conductive path including a first other-surface-side electrode constituting the first piezoelectric vibrator from the oscillation circuit and an impedance of a conductive path including a second other-surface-side electrode constituting the second piezoelectric vibrator from the oscillation circuit are uniform with each other.