Abstract: The invention relates to an ophthalmic agent comprising, as an active ingredient, a compound having a cardiotonic action including a phenyl pyridazinone derivative or salt thereof, or a hydrate thereof or solvate thereof as a typical example. Specifically, the invention relates to a preventative and/or therapeutic agent for optic nerve diseases or retinal diseases.

Abstract: This invention is aimed at providing a novel medicine for oculopathy, which has as an active component thereof a 5-HT.sub.1A receptor ligand such as, for example, an alkylene dioxybenzene derivative represented by the following formula (I) ##STR1## wherein m represents an integer in the range of 2-5 and n an integer in the range of 1-3), a racemate thereof, or an acid addition salt thereof.

Abstract: A lacrimation accelerating agent containing a ligand of serotonin receptor as an active ingredient. Also provided is a method for preventive and/or therapeutic treatment of a disease caused by a deficiency of lacrimal fluid such as dry eye, which comprises the step of administering to a mammal an effective amount of a ligand of a serotonin receptor such as sarpogrelate hydrochloride.

Abstract: A novel use of the compound of the formula ##STR1## wherein R.sub.1 is hydrogen atom or lower alkyl and R.sub.2 is hydrogen atom or phosphoric acid group, or a pharmacologically acceptable salt thereof for preventing and treating cataract. The compounds of the formula (I) and pharmacologically acceptable salts thereof of the present invention inhibit initial changes in the lens, such as vacuolation and trochoidal change, and almost completely inhibit a decrease in the amounts of reduced glutathione and cysteine in the lens, so that they are advantageously used for the prevention of the onset and progress of cataract.