Patents by Inventor Shunji Takehana

Shunji Takehana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzamidine compound
    Patent number: 8227506
    Abstract: Compounds represented by formula (1) and pharmaceutically acceptable salt thereofs: wherein each symbol is as defined in the specification, are useful as inhibitors of an activated blood coagulation factor X. Compositions which contain, as an active ingredient, an FXa selective low-molecular weight FXa inhibitor having a short serum half-life are particularly useful as anticoagulants for an extracorporeal blood circuit.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: July 24, 2012
    Assignee: Ajinomoto., Inc.
    Inventors: Masaru Takayanagi, Shunji Takehana, Kayo Otani, Yuki Saitou
  • NOVEL BENZAMIDINE COMPOUND
    Publication number: 20100105731
    Abstract: Compounds represented by formula (1) and pharmaceutically acceptable salt thereofs: wherein each symbol is as defined in the specification, are useful as inhibitors of an activated blood coagulation factor X. Compositions which contain, as an active ingredient, an FXa selective low-molecular weight FXa inhibitor having a short serum half-life are particularly useful as anticoagulants for an extracorporeal blood circuit.
    Type: Application
    Filed: August 2, 2007
    Publication date: April 29, 2010
    Applicant: Ajinomoto Co., Inc.
    Inventors: Masaru TAKAYANAGI, Shunji TAKEHANA, Kayo OTANI, Yuki SAITOU
  • Benzamidine derivatives
    Patent number: 7396844
    Abstract: Benzamidine derivatives of the following formulae or analogs thereof, i.e., pharmaceutically acceptable salts thereof, are provided.
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: July 8, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masaru Takayanagi, Kazuyuki Sagi, Tadakiyo Nakagawa, Masahiro Yamanashi, Takashi Kayahara, Shunji Takehana, Yumiko Fukuda, Mitsuo Takahashi, Masataka Shoji
  • NOVEL BENZAMIDINE COMPOUND
    Publication number: 20080021065
    Abstract: Compounds represented by formula (1) and pharmaceutically acceptable salt thereofs: wherein each symbol is as defined in the specification, are useful as inhibitors of an activated blood coagulation factor X. Compositions which contain, as an active ingredient, an FXa selective low-molecular weight FXa inhibitor having a short serum half-life are particularly useful as anticoagulants for an extracorporeal blood circuit.
    Type: Application
    Filed: August 2, 2007
    Publication date: January 24, 2008
    Applicant: AJINOMOTO CO. INC
    Inventors: Masaru Takayanagi, Shunji Takehana, Kayo Otani, Yuki Saitou
  • Aminoisoquinoline derivatives
    Patent number: 6825181
    Abstract: Aminoisoquinoline derivatives of the following formulae or analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an excellent effect of inhibiting activated blood-coagulation factor X, and they are useful as anticoagulants or agents for preventing or treating thrombi or emboli.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: November 30, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tadakiyo Nakagawa, Shingo Makino, Kazuyuki Sagi, Masaru Takayanagi, Takashi Kayahara, Shunji Takehana
  • Benzodiazepine derivatives
    Patent number: 6825191
    Abstract: The present invention provides benzodiazepine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of inhibiting activated blood-coagulation factor X. These compounds are usable as agents for treating various diseases concerned with the activated blood-coagulation factor X.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: November 30, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tadakiyo Nakagawa, Munetaka Tokumasu, Kazumi Tashiro, Mitsuo Takahashi, Takashi Kayahara, Shunji Takehana, Yuki Kajigaya, Kaoru Yoshida, Kuniya Sakurai
  • Benzamidine derivative
    Patent number: 6812231
    Abstract: Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases caused by thrombi or emboli.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: November 2, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tadakiyo Nakagawa, Kazuyuki Sagi, Kaoru Yoshida, Yumiko Fukuda, Masataka Shoji, Shunji Takehana, Takashi Kayahara, Akira Takahara
  • Amidinophenylpyruvic acid derivatives
    Patent number: 6710056
    Abstract: An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood coagulation factor VII.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: March 23, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masayuki Sugiki, Kazuyuki Sagi, Kohichi Fujita, Takashi Kayahara, Shunji Takehana, Kuniya Sakurai, Kazumi Tashiro
  • Benzodiazepine derivatives
    Publication number: 20030186969
    Abstract: The present invention provides benzodiazepine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of inhibiting activated blood-coagulation factor X. These compounds are usable as agents for treating various diseases concerned with the activated blood-coagulation factor X.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 2, 2003
    Applicant: AJINOMOTO CO. INC
    Inventors: Tadakiyo Nakagawa, Munetaka Tokumasu, Kazumi Tashiro, Mitsuo Takahashi, Takashi Kayahara, Shunji Takehana, Yuki Kajigaya, Kaoru Yoshida, Kuniya Sakurai
  • Amidinophenylpyruvic acid derivatives
    Publication number: 20030109547
    Abstract: An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood coagulation factor VII.
    Type: Application
    Filed: June 5, 2002
    Publication date: June 12, 2003
    Applicant: AJINOMOTO CO. INC
    Inventors: Masayuki Sugiki, Kazuyuki Sagi, Kohichi Fujita, Takashi Kayahara, Shunji Takehana, Kuniya Sakurai, Kazumi Tashiro
  • Benzamidine derivative
    Publication number: 20020107290
    Abstract: Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases caused by thrombi or emboli.
    Type: Application
    Filed: February 14, 2002
    Publication date: August 8, 2002
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tadakiyo Nakagawa, Kazuyuki Sagi, Kaoru Yoshida, Yumiko Fukuda, Masataka Shoji, Shunji Takehana, Takashi Kayahara, Akira Takahara
  • Benzamidine derivatives
    Patent number: 6410538
    Abstract: Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases caused by thrombi or emboli.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: June 25, 2002
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tadakiyo Nakagawa, Kazuyuki Sagi, Kaoru Yoshida, Yumiko Fukuda, Masataka Shoji, Shunji Takehana, Takashi Kayahara, Akira Takahara
  • Benzamidine derivatives
    Publication number: 20010056123
    Abstract: Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases caused by thrombi or emboli.
    Type: Application
    Filed: December 8, 2000
    Publication date: December 27, 2001
    Applicant: AJINOMOTO CO., INC
    Inventors: Tadakiyo Nakagawa, Kazuyuki Sagi, Kaoru Yoshida, Yumiko Fukuda, Masataka Shoji, Shunji Takehana, Takashi Kayahara, Akira Takahara