Patents by Inventor Shunji Yunoki

Shunji Yunoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11753462
    Abstract: The present invention relates to a highly oriented collagen fibril bundle having a length in a major axis direction of 1 m or more.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: September 12, 2023
    Assignee: Tokyo Metropolitan Industrial Technology Research Institute
    Inventors: Shunji Yunoki, Mizue Ebisawa, Eiji Kondo, Kazunori Yasuda
  • Patent number: 11559602
    Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: January 24, 2023
    Assignees: Tokyo Metropolitan Industrial Technology Research Institute, National University Corporation Gunma University
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Patent number: 10933171
    Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 2, 2021
    Assignees: Tokyo Metropolitan Industrial Technology Research Institute, National University Corporation Gunma University
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Publication number: 20200354432
    Abstract: The present invention relates to a highly oriented collagen fibril bundle having a length in a major axis direction of 1 m or more.
    Type: Application
    Filed: November 5, 2018
    Publication date: November 12, 2020
    Inventors: Shunji Yunoki, Mizue Ebisawa, Eiji Kondo, Kazunori Yasuda
  • Patent number: 10815393
    Abstract: A gelatin or a chemically modified product thereof contains 10 to 50% by mass of a high-molecular weight component, and a low-molecular weight component in such an amount that a value obtained by subtracting a low-molecular weight component content from a high-molecular weight component content is greater than or equal to 0% by mass.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: October 27, 2020
    Assignees: TOKYO METROPOLITAN INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NITTA GELATIN INC.
    Inventors: Yoshimi Ohyabu, Shunji Yunoki, Hirosuke Hatayama, Masataka Ida, Yosuke Hiraoka
  • Publication number: 20190343992
    Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.
    Type: Application
    Filed: November 16, 2017
    Publication date: November 14, 2019
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Publication number: 20190290808
    Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.
    Type: Application
    Filed: November 16, 2017
    Publication date: September 26, 2019
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Publication number: 20180312726
    Abstract: A gelatin or a chemically modified product thereof contains 10 to 50% by mass of a high-molecular weight component, and a low-molecular weight component in such an amount that a value obtained by subtracting a low-molecular weight component content from a high-molecular weight component content is greater than or equal to 0% by mass.
    Type: Application
    Filed: October 18, 2016
    Publication date: November 1, 2018
    Inventors: Yoshimi OHYABU, Shunji YUNOKI, Hirosuke HATAYAMA, Masataka ODA, Yosuke HIRAOKA
  • Patent number: 8105629
    Abstract: The present invention relates to a process of producing a collagen gel comprising collagen fibers cross-linked with each other by a cross-linking agent on the way of fibrosis of collagen, and a collagen gel comprising the cross-linked collagen fibers obtained by the process. The collagen gel comprising cross-linked collagen fibers of the present invention has high strength and thermal stability and can be widely used as cell carriers and medical materials.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: January 31, 2012
    Assignee: Ihara & Company Ltd.
    Inventors: Shunji Yunoki, Nobuhiro Nagai
  • Publication number: 20060210601
    Abstract: The present invention provides a stretchable collagen material, particularly collagen derived from fishes, having excellent stretching property and mechanical strength, which can be widely used as a cell carrier and medical material, and to a method for manufacturing the same. By thermally treating a gel comprising collagen fiber cross-linked by using cross-linking agent, the collagen enhanced in both stretching property and mechanical strength can be produced. The stretchable collagen material is extremely useful as a cell carrier material and medical material.
    Type: Application
    Filed: April 27, 2005
    Publication date: September 21, 2006
    Applicant: Ihara & Company Ltd.
    Inventors: Shunji Yunoki, Nobuhiro Nagai
  • Publication number: 20060177492
    Abstract: The present invention relates to a process of producing a collagen gel comprising collagen fibers cross-linked with each other by a cross-linking agent on the way of fibrosis of collagen, and a collagen gel comprising the cross-linked collagen fibers obtained by the process. The collagen gel comprising cross-linked collagen fibers of the present invention has high strength and thermal stability and can be widely used as cell carriers and medical materials.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 10, 2006
    Applicant: IHARA & COMPANY LTD
    Inventors: Shunji Yunoki, Nobuhiro Nagai
  • Publication number: 20050214374
    Abstract: The artificial extracellular matrix of the present invention comprises heat stable fish collagen produced from fish collagen with a heat denaturation temperature lower than 37° C. by improving its heat stability. The artificial extracellular matrix of the invention has an adequate stability in living bodies and a function to activate tissue repair at a high level and requires no addition of heat denatured collagen. In addition, the artificial extracellular matrix is unlikely to contain pathogenic organisms because it uses collagen originated from fish.
    Type: Application
    Filed: May 14, 2002
    Publication date: September 29, 2005
    Inventors: Mitsuo Takai, Tomoki Erata, Shunji Yunoki, Tatsuya Fujita
  • Patent number: 6699574
    Abstract: A polypropylene-based resin composition for stretched film, comprising 20 to 98 parts by weight of a propylene-based polymer(A) having an intrinsic viscosity [&eegr;]A of 1.8 to 8 dl/g and a melting temperature TmA of 140 to 165 ° C. and 2 to 80 parts by weight of a propylene-based polymer(B) having an intrinsic viscosity [&eegr;]B of 0.8 to 1.7 dl/g and a melting temperature TmB of 150 to 170° C., wherein the ratio of TmA to TmB is less than 1, the ratio of the intrinsic viscosity [&eegr;]A to the intrinsic viscosity [&eegr;]B is more than 1 and less than 10, and the melt flow rate of the polypropylene-based resin composition is from 0.1 to 20 g/10 min.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: March 2, 2004
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yoichi Obata, Shunji Yunoki, Takeshi Ebara
  • Patent number: 6639018
    Abstract: A polypropylene resin composition having a melt flow rate of 0.5 to 20 g/10 min., comprising 20 to 98 parts by weight of a propylene-based polymer (A) having an intrinsic viscosity [&eegr;] measured in tetralin at 135° C. of 2.0 to 5 dl/g and a melting point Tm determined from the peak temperature of the melting curve measured by a differential scanning calorie meter of 140 to 162° C. and 2 to 80 parts by weight of a propylene-based polymer B having an intrinsic viscosity [&eegr;] measured in tetralin at 135° C. of 0.80 to 1.8 dl/g and a melting point Tm determined from the peak temperature of the melting curve measured by a differential scanning calorie meter of 160 to 166° C. and a process for producing the same.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: October 28, 2003
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Shunji Yunoki, Takeshi Ebara, Yoichi Obata
  • Publication number: 20030055173
    Abstract: A polypropylene-based resin composition for stretched film, comprising 20 to 98 parts by weight of a propylene-based polymer(A) having an intrinsic viscosity [&eegr;]A of 1.8 to 8 dl/g and a melting temperature TmA of 140 to 165 ° C. and 2 to 80 parts by weight of a propylene-based polymer(B) having an intrinsic viscosity [&eegr;]B of 0.8 to 1.7 dl/g and a melting temperature TmB of 150 to 170° C., wherein the ratio of TmA to TmB is less than 1, the ratio of the intrinsic viscosity [&eegr;]A to the intrinsic viscosity [&eegr;]B is more than 1 and less than 10, and the melt flow rate of the polypropylene-based resin composition is from 0.1 to 20 g/10 min.
    Type: Application
    Filed: March 18, 2002
    Publication date: March 20, 2003
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Yoichi Obata, Shunji Yunoki, Takeshi Ebara
  • Publication number: 20020177657
    Abstract: A polypropylene resin composition having a melt flow rate of 0.5 to 20 g/10 min., comprising 20 to 98 parts by weight of a propylene-based polymer (A) having an intrinsic viscosity [&eegr;] measured in tetralin at 135° C. of 2.0 to 5 dl/g and a melting point Tm determined from the peak temperature of the melting curve measured by a differential scanning calorie meter of 140 to 162° C. and 2 to 80 parts by weight of a propylene-based polymer B having an intrinsic viscosity [&eegr;] measured in tetralin at 135° C. of 0.80 to 1.8 dl/g and a melting point Tm determined from the peak temperature of the melting curve measured by a differential scanning calorie meter of 160 to 166° C. and a process for producing the same.
    Type: Application
    Filed: February 25, 2002
    Publication date: November 28, 2002
    Inventors: Shunji Yunoki, Takeshi Ebara, Yoichi Obata