Patents by Inventor Shunqi Yan

Shunqi Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compounds and compositions
    Patent number: 8785450
    Abstract: Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: July 22, 2014
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Francesco G. Salituro, Jeffrey O. Saunders, Shunqi Yan
  • COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20140142146
    Abstract: Compounds and compositions comprising compounds that inhibit glutaminase are described herein. Also described herein are methods of using the compounds that inhibit glutaminase in the treatment of cancer.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 22, 2014
    Applicant: AGIOS PHARMACEUTICALS, INC
    Inventors: Rene M. Lemieux, Janeta Popovici-Muller, Francesco G. Salituro, Jeffrey O. Saunders, Jeremy Travins, Shunqi Yan
  • Pyridone sulfonamides and pyridone sulfamides as MEK inhibitors
    Patent number: 8716318
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: May 6, 2014
    Assignee: Ardea Biosciences
    Inventors: Shunqi Yan, Jean-Michel Vernier, Zhi Hong, Suetying Chow, Yung-hyo Koh
  • Dihydropyridin sulfonamides and dihydropyridin sulfamides as MEK inhibitors
    Patent number: 8673919
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: March 18, 2014
    Assignee: Ardea Biosciences, Inc.
    Inventors: Jean-Michel Vernier, Hong Woo Kim, Marion Hitchcock, Shunqi Yan
  • NOVEL N-(4-(AZETIDINE-1-CARBONYL) PHENYL) - (HETERO-) ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS
    Publication number: 20140073625
    Abstract: Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
    Type: Application
    Filed: December 16, 2011
    Publication date: March 13, 2014
    Applicant: AGIOS PHARMACEUTICALS, INC
    Inventors: Francesco G. Salituro, Jeffrey O. Saunders, Shunqi Yan
  • THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE
    Publication number: 20130184222
    Abstract: Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1 comprising administering to a subject in need thereof a compound described here.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 18, 2013
    Applicant: AGIOS PHARMACEUTICALS, INC
    Inventors: Janeta Popovici-Muller, Francesco G. Salituro, Jeffrey Saunders, Jeremy Travins, Shunqi Yan
  • THERAPEUTIC COMPOUNDS AND COMPOSITIONS
    Publication number: 20120172349
    Abstract: Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
    Type: Application
    Filed: December 29, 2011
    Publication date: July 5, 2012
    Inventors: Francesco G. Salituro, Jeffrey Saunders, Shunqi Yan
  • DIHYDROPYRIDIN SULFONAMIDES AND DIHYDROPYRIDIN SULFAMIDES AS MEK INHIBITORS
    Publication number: 20120107307
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Application
    Filed: March 23, 2010
    Publication date: May 3, 2012
    Applicant: ARDEA BIOSCIENCES INC.
    Inventors: Jean-Michel Vernier, Hong Woo Kim, Marion Hitchcock, Shunqi Yan
  • PYRIDONE SULFONAMIDES AND PYRIDONE SULFAMIDES AS MEK INHIBITORS
    Publication number: 20110112152
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 12, 2011
    Inventors: Shunqi Yan, Jean-Michel Vemier, Zhi Hong, Suetying Chow, Yung-hyo Koh
  • Pyridone sulfonamides and pyridone sulfamides as MEK inhibitors
    Patent number: 7897624
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: March 1, 2011
    Assignee: Ardea Biosciences
    Inventors: Shunqi Yan, Jean-Michel Vernier, Zhi Hong, Suetying Chow, Yung-hyo Koh
  • THERAPEUTIC COMPOUNDS AND COMPOSITIONS
    Publication number: 20100331307
    Abstract: Compounds and compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
    Type: Application
    Filed: June 29, 2010
    Publication date: December 30, 2010
    Inventors: Francesco G. Salituro, Jeffrey O. Saunders, Shunqi Yan
  • N-aryl-N'alkyl sulfamides as MEK inhibitors
    Patent number: 7842836
    Abstract: This invention concerns N-(ortho phenylaminoaryl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: November 30, 2010
    Assignee: Ardea Biosciences
    Inventors: Shunqi Yan, Jean-Michel Vernier, Zhi Hong
  • PYRIDONE SULFONAMIDES AND PYRIDONE SULFAMIDES AS MEK INHIBITORS
    Publication number: 20070244164
    Abstract: This invention concerns N-(ortho phenylamino dihydropyridyl)sulfonamides and N-(ortho phenylamino dihydropyridyl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Application
    Filed: April 18, 2007
    Publication date: October 18, 2007
    Applicant: ARDEA BIOSCIENCES
    Inventors: Shunqi Yan, Jean-Michel Vernier, Zhi Hong, Suetying Chow, Yung-hyo Koh
  • N-ARYL-N'ALKYL SULFAMIDES AS MEK INHIBITORS
    Publication number: 20070238710
    Abstract: This invention concerns N-(ortho phenylaminoaryl), N?-alkyl sulfamides which are inhibitors of MEK and are useful in the treatment of cancer and other hyperproliferative diseases.
    Type: Application
    Filed: April 11, 2007
    Publication date: October 11, 2007
    Applicant: ARDEA BIOSCIENCES
    Inventors: Shunqi Yan, Jean-Michel Vernier, Zhi Hong
  • Cycloalkl, aryl and heteroaryl amino isothiazoles for the treatment of Hepatitis C virus
    Publication number: 20060217390
    Abstract: This invention concerns certain 5-(substituted amino) isothiazoles, compounds of Formula I, and salts thereof, where Q is CN, NHCONRaRb, or CONRaRb, where Ra and Rb are defined herein; and R1 is cyclohexyl, adamantan-1-yl, indan-1-yl, phenyl, benzyl, pyridyl, pyridylmethyl, or pyrimidyl, where all aromatic R1 groups are optionally substituted, provided that when R1 is phenyl, then R1 bears at least one non-alkyl substituent, and further provided that R1 is not 4-chloro-3-trichloromethyl-phenyl; The invention also concerns the tautomeric 5-(substituted amino)-isothiazol-3(2H)-ones, and the use of such compounds to treat Hepatitis C infection. It also concerns thiocarbamoyl acetamides, which are synthetic precursors to the isothiazoles.
    Type: Application
    Filed: February 24, 2006
    Publication date: September 28, 2006
    Inventors: Esmir Gunic, Todd Appleby, Weidong Zhong, Shunqi Yan, Ching Lai