Abstract: A gastrointestinal-tract constricting method comprises: while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, placing a protection substance, which does not damage tissue, in at least one of a region between the mucosal layer and muscular layer of the gastrointestinal tract and a region in a mucosal surface of the mucosal layer so as to form a protection region that protects the mucosa basal layer from a medical substance that damages the tissue; and, after forming the protection region, supplying the medical substance to a mucosal surface in a target region, which is at a position different from the protection region in a circumferential direction of the gastrointestinal tract, or to a position between the mucosal layer and the muscular layer.

Abstract: A drug supply device includes: a tube body; a first expansion member configured to be expanded to a first outer diameter and a second expansion member configured to be expanded to a second outer diameter that is greater than the first outer diameter, the first expansion member and the second expansion member being positioned on a distal-end side of the tube body; and a masking member that extends between the expansion members and that is connected to outer surfaces of the expansion members at two ends thereof. The tube body includes an outlet that opens between the expansion members and a channel that is in communication with the outlet, the masking member is formed in an arc shape in a lateral cross-section that is orthogonal to the longitudinal axis, and the masking member stretches between the expansion members in a state in which the expansion members are expanded.

Abstract: A gastrointestinal tract constricting method according to the present invention aims to constrict the gastrointestinal tract by contracting a desired region of the gastrointestinal tract by a simple and low-invasive procedure. The method includes forming spreading blocks while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, the spreading blocks being formed at a position between a mucosa layer and a muscle layer and on both sides of a target region, which is to be damaged by a substance, in a circumferential direction of the gastrointestinal tract so that the spreading blocks block spreading of the substance in the circumferential direction of the gastrointestinal tract to prevent spreading of the substance to an outer side of the target region, and supplying the substance to a mucosal surface of the target region or to the position between the mucosa layer and the muscle layer after formation of the spreading blocks.

Abstract: A gastrointestinal-tract constricting method includes: while observing the gastrointestinal tract by inserting an endoscope into the gastrointestinal tract, forming a spreading block that suppresses infiltration of a substance, which damages a mucosa basal layer of the gastrointestinal tract, into the muscular layer underlying the mucosa basal layer, the spreading block being formed along a circumferential direction of the gastrointestinal tract and between the mucosa basal layer and the muscular layer; and supplying the substance to a gap between the spreading block and the mucosa basal layer while forming a contact surface between the spreading block and the substance along the circumferential direction of the gastrointestinal tract.

Abstract: A gastrointestinal-tract constricting method includes, while observing the gastrointestinal tract by inserting an endoscope into the gastrointestinal tract, forming a spreading block that blocks infiltration of a substance, which damages a mucosa basal layer of the gastrointestinal tract, into the muscular layer underlying the mucosa basal layer, the spreading block being formed along a circumferential direction of the gastrointestinal tract and between the mucosa basal layer and the muscular layer; and supplying the substance along the circumferential direction of the gastrointestinal tract and to a surface of the mucosa that lies within a region that overlaps an inner side of the gastrointestinal tract with respect to the spreading block out of the entire circumference of the gastrointestinal tract in a transverse section of the gastrointestinal tract.

Abstract: A gastrointestinal-tract constricting method comprises: while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, placing a protection substance, which does not damage tissue, in at least one of a region between the mucosal layer and muscular layer of the gastrointestinal tract and a region in a mucosal surface of the mucosal layer so as to form a protection region that protects the mucosa basal layer from a medical substance that damages the tissue; and, after forming the protection region, supplying the medical substance to a mucosal surface in a target region, which is at a position different from the protection region in a circumferential direction of the gastrointestinal tract, or to a position between the mucosal layer and the muscular layer.

Abstract: A gastrointestinal-tract constricting method includes, while observing the gastrointestinal tract by inserting an endoscope into the gastrointestinal tract, forming a spreading block that blocks infiltration of a substance, which damages a mucosa basal layer of the gastrointestinal tract, into the muscular layer underlying the mucosa basal layer, the spreading block being formed along a circumferential direction of the gastrointestinal tract and between the mucosa basal layer and the muscular layer; and supplying the substance along the circumferential direction of the gastrointestinal tract and to a surface of the mucosa that lies within a region that overlaps an inner side of the gastrointestinal tract with respect to the spreading block out of the entire circumference of the gastrointestinal tract in a transverse section of the gastrointestinal tract.

Abstract: A gastrointestinal-tract constricting method includes: while observing the gastrointestinal tract by inserting an endoscope into the gastrointestinal tract, forming a spreading block that suppresses infiltration of a substance, which damages a mucosa basal layer of the gastrointestinal tract, into the muscular layer underlying the mucosa basal layer, the spreading block being formed along a circumferential direction of the gastrointestinal tract and between the mucosa basal layer and the muscular layer; and supplying the substance to a gap between the spreading block and the mucosa basal layer while forming a contact surface between the spreading block and the substance along the circumferential direction of the gastrointestinal tract.

Abstract: A gastrointestinal tract constricting method according to the present invention aims to constrict the gastrointestinal tract by contracting a desired region of the gastrointestinal tract by a simple and low-invasive procedure. The method includes forming spreading blocks while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, the spreading blocks being formed at a position between a mucosa layer and a muscle layer and on both sides of a target region, which is to be damaged by a substance, in a circumferential direction of the gastrointestinal tract so that the spreading blocks block spreading of the substance in the circumferential direction of the gastrointestinal tract to prevent spreading of the substance to an outer side of the target region, and supplying the substance to a mucosal surface of the target region or to the position between the mucosa layer and the muscle layer after formation of the spreading blocks.

Abstract: An endoscopic treatment tool includes: a tubular insertion part; a stopper having a through hole and provided at a distal end part of the insertion part; a manipulation wire inserted through the insertion part; a treatment part provided at a distal end part of the manipulation wire and inserted through the through hole; and a restriction member provided closer to a proximal end side than the stopper and connecting the treatment part and the manipulation wire. When the restriction member is pressed against the stopper, the treatment part is locked not to be rotated about an axis of the insertion part with respect to the insertion part, and an opening causing a fluid to flow from an inside of the insertion part to the through hole is formed on an outer peripheral surface of the restriction member.

Abstract: Provided is a high-frequency treatment tool. A positioning member that regulates movement of a second wire part within a sheath relative to a first wire part in a direction of a longitudinal axis of the second wire part is present in the sheath. In a state in which a folded part is located close to a distal end of the sheath, a loop formation part is fed from the distal end of the sheath with the second wire part fixed.

Abstract: Provided is a high-frequency treatment tool including a cylindrical sheath, an electrode member that is made to protrude and be retracted with respect to a distal-end portion of the sheath, and a liquid-feeding unit for feeding a liquid toward the distal-end side inside a flow channel in the sheath, wherein a distal end of the electrode member is provided with a distal-end expanded portion that extends radially outward in a radiating manner and that has a base-end surface that is made to protrude and be retracted with respect to a distal-end portion of the sheath, wherein the sheath is provided with a restricting portion that restricts the movement of the electrode member toward the base-end side at a position at which a portion of the distal-end expanded portion is accommodated inside the sheath and an accommodating portion that can accommodate at least a portion of the distal-end expanded portion.

Abstract: Provided is a high-frequency treatment tool including a cylindrical sheath, an electrode member that is made to protrude and be retracted with respect to a distal-end portion of the sheath, and a liquid-feeding unit for feeding a liquid toward the distal-end side inside a flow channel in the sheath, wherein a distal end of the electrode member is provided with a distal-end expanded portion that extends radially outward in a radiating manner and that has a base-end surface that is made to protrude and be retracted with respect to a distal-end portion of the sheath, wherein the sheath is provided with a restricting portion that restricts the movement of the electrode member toward the base-end side at a position at which a portion of the distal-end expanded portion is accommodated inside the sheath and an accommodating portion that can accommodate at least a portion of the distal-end expanded portion.

Abstract: An endoscope procedure instrument provided with: a tube part that is cylindrical in shape and attaches to the front end of the endoscope, the tube part having a slit provided to the side surface thereof extending along the direction of the central axis; and a grasping member that is disposed to the tube part extending along the slit, for holding a biologic tissue with respect to the endoscope.

Abstract: An endoscope treatment tool includes a treatment portion, a manipulation portion, and a manipulation wire connecting the treatment portion and the manipulation portion, the manipulation portion includes a manipulation portion main body, a shaft, a clutch plate having a through-hole into which the shaft is slidably inserted, a manipulation member slidably attached to the manipulation portion main body, and a force adjustment member compressed in accordance with manipulation of the manipulation member, and the clutch plate is inclined with respect to the shaft in accordance with compression of the force adjustment member, and thereby the manipulation member is fixed to the manipulation portion main body by the clutch plate which is fixed to the shaft so as not to slide with respect to the shaft.

Abstract: A treatment tool for an endoscope includes a sheath member, a treatment part, an operating part body, an operating wire, a slider, and a force limiting part. When a predetermined force is applied to the force limiting part with advance and refraction of the slider, the force limiting part engages a wall surface of the insertion passage of the operating wire and fixes the slider by being compressed in an advance-and-retraction direction and expanding in a radial direction.

Abstract: An endoscope procedure instrument provided with: a tube part that is cylindrical in shape and attaches to the front end of the endoscope, the tube part having a slit provided to the side surface thereof extending along the direction of the central axis; and a grasping member that is disposed to the tube part extending along the slit, for holding a biologic tissue with respect to the endoscope.

Abstract: An endoscope procedure instrument provided with: a tube part that is cylindrical in shape and attaches to the front end of the endoscope, the tube part having a slit provided to the side surface thereof extending along the direction of the central axis; and a grasping member that is disposed to the tube part extending along the slit, for holding a biologic tissue with respect to the endoscope.

Abstract: An endoscope treatment tool includes a treatment portion, a manipulation portion, and a manipulation wire connecting the treatment portion and the manipulation portion, the manipulation portion includes a manipulation portion main body, a shaft, a clutch plate having a through-hole into which the shaft is slidably inserted, a manipulation member slidably attached to the manipulation portion main body, and a force adjustment member compressed in accordance with manipulation of the manipulation member, and the clutch plate is inclined with respect to the shaft in accordance with compression of the force adjustment member, and thereby the manipulation member is fixed to the manipulation portion main body by the clutch plate which is fixed to the shaft so as not to slide with respect to the shaft.

Abstract: A treatment tool for an endoscope includes a sheath member, a treatment part, an operating part body, an operating wire, a slider, and a force limiting part. When a predetermined force is applied to the force limiting part with advance and refraction of the slider, the force limiting part engages a wall surface of the insertion passage of the operating wire and fixes the slider by being compressed in an advance-and-retraction direction and expanding in a radial direction.