Patents by Inventor Shunya Oka

Shunya Oka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADP-ribosyl acceptor hydrolase 3 (ARH3) polypeptides and methods of use
    Patent number: 7670806
    Abstract: This disclosure provides methods for catalyzing the release of ADP-ribose from poly(ADP-ribose) or O-acetyl-ADP-ribose. Also provided are methods for modifying DNA repair or chromatin structure by introducing into the cell an agent that modifies the activity of an ARH3 polypeptide, or variant or fragment thereof. Further provided are methods for screening molecules involved in the poly(ADP-ribosyl)ation of proteins or O-acetyl-ADP-ribose content, and method for treating disorders by altering activity of an ARH3 protein.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: March 2, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Joel Moss, Shunya Oka, Jiro Kato, Jianfeng Zhu, Atsushi Kasamatsu
  • HYDROLASE AND METHODS FOR ITS USE
    Publication number: 20080207555
    Abstract: This disclosure provides methods for catalyzing the release of ADP-ribose from poly(ADP-ribose) or O-acetyl-ADP-ribose. Also provided are methods for modifying DNA repair or chromatin structure by introducing into the cell an agent that modifies the activity of an ARH3 polypeptide, or variant or fragment thereof. Further provided are methods for screening molecules involved in the poly(ADP-ribosyl)ation of proteins or O-acetyl-ADP-ribose content, and method for treating disorders by altering activity of an ARH3 protein.
    Type: Application
    Filed: March 12, 2008
    Publication date: August 28, 2008
    Inventors: Joel Moss, Shunya Oka, Jiro Kato, Jianfeng Zhu, Atsushi Kasamatsu