Patents by Inventor Shuo Xiao

Shuo Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING, PREVENTING, AND/OR AMELIORATING CHEMOTHERAPY-INDUCED PREMATURE OVARIAN FAILURE (POF)
    Publication number: 20230062911
    Abstract: In one aspect, the present disclosure provides a method of treating, preventing, and/or ameliorating premature ovarian failure (POF) in a subject in need thereof, wherein the subject is a female cancer patient being administered at least one chemotherapeutic drug, the method comprising administering to the subject at least one c-Jun N-terminal Kinase (JNK) inhibitor. In certain embodiments, the JNK inhibitor is SP600125. In another aspect, the present disclosure provides a pharmaceutical composition comprising a JNK inhibitor.
    Type: Application
    Filed: September 2, 2022
    Publication date: March 2, 2023
    Applicant: Rutgers, The State University of New Jersey
    Inventor: Shuo Xiao
  • 3D microphysiologic system
    Patent number: 11542475
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: January 3, 2023
    Assignees: The Board of Trustees of the University of Illinois, Northwestern University
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu
  • 3D MICROPHYSIOLOGIC SYSTEM
    Publication number: 20200190479
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Application
    Filed: October 21, 2019
    Publication date: June 18, 2020
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu
  • 3D microphysiologic system
    Patent number: 10526578
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: January 7, 2020
    Assignees: Northwestern University, The Board of Trustees of the University of Illinois
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu
  • 3D MICROPHYSIOLOGIC SYSTEM
    Publication number: 20180057796
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Application
    Filed: June 30, 2017
    Publication date: March 1, 2018
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu
  • 3D microphysiologic system
    Patent number: 9695399
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: July 4, 2017
    Assignees: Northwestern University, Board of Trustees of the University of Illinois
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu
  • 3D MICROPHYSIOLOGIC SYSTEM
    Publication number: 20150252328
    Abstract: The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system.
    Type: Application
    Filed: January 28, 2015
    Publication date: September 10, 2015
    Inventors: Teresa K. Woodruff, Ji-Yong Julie Kim, Joanna E. Burdette, Spiro Getsios, Sevim Yildiz Arslan, Shuo Xiao, Jie Zhu