Patents by Inventor Shuqi Chen

Shuqi Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10459127
    Abstract: Provided are a Fourier lens, a method for designing a Fourier lens, and a schlieren apparatus. The Fourier lens includes a substrate and a plurality of cuboid waveguides. The plurality of waveguides are arranged on the substrate in parallel and spaced from each other at a preset interval. The material of the substrate and the material of the waveguides are all transparent to the working waveband of the Fourier lens. The preset interval is smaller than a quotient obtained by dividing a center wavelength of the working waveband by the refractive index of the substrate. The waveguide has a plurality of widths, and the waveguides of different widths correspond to different phase delays. The individual waveguides are arranged on the substrate according to phase delays required at different positions. According to the embodiments, the range of the working angle of the Fourier lens can be increased.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: October 29, 2019
    Assignee: NANKAI UNIVERSITY
    Inventors: Shuqi Chen, Wenwei Liu, Hua Cheng, Jianguo Tian
  • Patent number: 10443050
    Abstract: A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: October 15, 2019
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Publication number: 20190041552
    Abstract: Provided are a Fourier lens, a method for designing a Fourier lens, and a schlieren apparatus. The Fourier lens includes a substrate and a plurality of cuboid waveguides. The plurality of waveguides are arranged on the substrate in parallel and spaced from each other at a preset interval. The material of the substrate and the material of the waveguides are all transparent to the working waveband of the Fourier lens. The preset interval is smaller than a quotient obtained by dividing a center wavelength of the working waveband by the refractive index of the substrate. The waveguide has a plurality of widths, and the waveguides of different widths correspond to different phase delays. The individual waveguides are arranged on the substrate according to phase delays required at different positions. According to the embodiments, the range of the working angle of the Fourier lens can be increased.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 7, 2019
    Inventors: Shuqi CHEN, Wenwei LIU, Hua CHENG, Jianguo TIAN
  • Patent number: 10022722
    Abstract: A sample vessel may include a segmented tubule having an opening for receiving a sample material and at least one compressible section, the at least one compressible section having a wall constructed at least partially from a material having sufficient flexibility to permit compression of opposed sections of the wall into contact, and at least two segments of the tubule being fluidically isolated from one another by a bonding of opposed sections of the tubule wall to one another. The sample vessel may also include an interface in fluid communication with the opening in the tubule, the interface facilitating delivery of a sample material to the tubule through the opening.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: July 17, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Publication number: 20170283790
    Abstract: A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 5, 2017
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 9708599
    Abstract: A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: July 18, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 9662652
    Abstract: Provided herein is a sample processing apparatus including a sample-containing vessel and a thermal cycling apparatus, wherein the vessel has at least 3 fluidically isolated segments that are each thermally conductive, compressible, and expandable. The thermal cycling unit is capable of amplifying extracted nucleic acid and has at least a first processing station and a second processing station, each processing station defining a temperature zone, wherein thermal cycling is performed by alternatively transferring the contents of the sample vessel between the at least two processing stations.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: May 30, 2017
    Assignee: Chen & Chen, LLC
    Inventor: Shuqi Chen
  • Publication number: 20150375225
    Abstract: A sample vessel may include a segmented tubule having an opening for receiving a sample material and at least one compressible section, the at least one compressible section having a wall constructed at least partially from a material having sufficient flexibility to permit compression of opposed sections of the wall into contact, and at least two segments of the tubule being fluidically isolated from one another by a bonding of opposed sections of the tubule wall to one another. The sample vessel may also include an interface in fluid communication with the opening in the tubule, the interface facilitating delivery of a sample material to the tubule through the opening.
    Type: Application
    Filed: April 1, 2015
    Publication date: December 31, 2015
    Inventors: Shuqi Chen, Lingjun Chen
  • Publication number: 20150105300
    Abstract: A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
    Type: Application
    Filed: December 17, 2014
    Publication date: April 16, 2015
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 9005551
    Abstract: A sample vessel may include a segmented tubule and an interface receiving the tubule. The segmented tubule may include an opening for receiving a sample material and at least one compressible section, the at least one compressible section having a wall constructed at least partially from a material having sufficient flexibility to permit compression of opposed sections of the wall into contact with one another, and at least two segments of the tubule being fluidically isolated from one another by a bonding of a fluid-tight seal between opposed sections of the tubule wall, wherein said fluid-tight seal irreversibly opens upon application of fluid pressure greater than a threshold value to permit selective fluid communication between the opposed sections. The interface may facilitate delivery of a sample material to the tubule through the opening.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: April 14, 2015
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 8936933
    Abstract: A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the proximal end of the vessel; incubating the sample in the vessel with a substance capable of specific binding to a preselected component of the sample; propelling components of the incubated sample, other than the preselected component, toward the proximal end of the vessel by clamping the vessel distal to the incubated sample and compressing the vessel where the incubated sample is contained; propelling the preselected component toward a distal segment of the vessel by clamping the vessel proximal to the preselected component and compressing the vessel where the preselected component is contained; and mixing the preselected component with a reagent in the distal segment of the vessel.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: January 20, 2015
    Assignee: IQumm, Inc.
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 8414845
    Abstract: A sample processing vessel may include a branch segment and at least two tracks. The at least two tracks may be fluidly isolated from one another by a permanent seal. The tracks may be segmented by breakable seals. The branch segment may be temporarily isolated from the tracks by breakable seal(s) and put in fluid communication with the tracks once those seal(s) are broken, such that fluid received by the branch segment is divided into portions that pass into both tracks.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: April 9, 2013
    Assignee: Iquum, Inc.
    Inventors: Shuqi Chen, Bertrand Lemieux, Lingjun Chen
  • Publication number: 20120276532
    Abstract: A sample processing device may include an opening, a sample pretreatment unit, a thermal cycling reaction unit, and a detection unit.
    Type: Application
    Filed: April 3, 2012
    Publication date: November 1, 2012
    Applicant: Chen & Chen, LLC
    Inventor: Shuqi Chen
  • Patent number: 8148116
    Abstract: A sample processing device may include an opening, a sample pretreatment unit, a thermal cycling reaction unit, and a detection unit.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 3, 2012
    Assignee: Chen & Chen, LLC
    Inventor: Shuqi Chen
  • Publication number: 20110207121
    Abstract: A sample processing device may include an opening, a sample pretreatment unit, a thermal cycling reaction unit, and a detection unit.
    Type: Application
    Filed: May 2, 2011
    Publication date: August 25, 2011
    Applicant: CHEN & CHEN, LLC
    Inventor: Shuqi Chen
  • Publication number: 20110143968
    Abstract: A sample vessel may include a segmented tubule and an interface receiving the tubule. The segmented tubule may include an opening for receiving a sample material and at least one compressible section, the at least one compressible section having a wall constructed at least partially from a material having sufficient flexibility to permit compression of opposed sections of the wall into contact with one another, and at least two segments of the tubule being fluidically isolated from one another by a bonding of a fluid-tight seal between opposed sections of the tubule wall, wherein said fluid-tight seal irreversibly opens upon application of fluid pressure greater than a threshold value to permit selective fluid communication between the opposed sections. The interface may facilitate delivery of a sample material to the tubule through the opening.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 16, 2011
    Applicant: IQUUM, INC.
    Inventors: Shuqi Chen, Lingjun Chen
  • Patent number: 7935504
    Abstract: A thermal cycling method may include adding a sample to a sample vessel, placing the sample vessel into a thermal cycler having a processing unit with three processing stations, compressing the sample vessel with the first compression member, transferring energy to the sample with the second energy transfer element, transferring energy to the sample with the third energy transfer element, compressing the sample vessel with the third compression member, and transferring energy to the sample with the first energy transfer element.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: May 3, 2011
    Assignee: Chen & Chen, LLC
    Inventor: Shuqi Chen
  • Publication number: 20110064613
    Abstract: A sample testing vessel may include a flexible plastic tube and a self-sealing injection channel. The flexible plastic tube may have a seal defining a first compartment and a second compartment, wherein the seal comprises a pressure gate providing a fluid-tight seal between first and second compartments and opening upon application of a threshold pressure. The injection channel may be normally substantially free of fluid and capable of fluid communication with the tubule.
    Type: Application
    Filed: November 16, 2010
    Publication date: March 17, 2011
    Applicant: CHEN & CHEN, LLC
    Inventor: Shuqi Chen
  • Publication number: 20100323919
    Abstract: A sample processing vessel may include a branch segment and at least two tracks. The at least two tracks may be fluidly isolated from one another by a permanent seal. The tracks may be segmented by breakable seals. The branch segment may be temporarily isolated from the tracks by breakable seal(s) and put in fluid communication with the tracks once those seal(s) are broken, such that fluid received by the branch segment is divided into portions that pass into both tracks.
    Type: Application
    Filed: August 30, 2010
    Publication date: December 23, 2010
    Applicant: IQUUM, INC.
    Inventors: Shuqi Chen, Bertrand Lemieux, Lingjun Chen
  • Patent number: 7833489
    Abstract: A sample testing system may include a vessel comprising at least two flexible compartments and a self-sealing injection channel. The injection channel may be capable of (a) being in fluid communication with at least one of the flexible compartments, and (b) being pierced by a needle in fluid communication with a reagent reservoir. The system may further include a housing, a cavity in the housing, so sized and shaped to receive the vessel, at least one contact member, and a sensor to sense a condition of a fluid sample in the vessel and to generate an output signal indicative of that condition. The contact member may be so positioned as to be engageable with one of the flexible compartments when the vessel is in the cavity and as to compress the engaged flexible compartment, thereby driving fluid flow from the engaged flexible compartment to the other of the at least two compartments of the vessel.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: November 16, 2010
    Assignee: Chen & Chen, LLC
    Inventor: Shuqi Chen