Abstract: A system and method deliver fluidized powder based on flue gas carrying waste slag and instant cooling steel slag. A first flue gas pipeline receives pressurized CO2-rich flue gas and in fluid communication with a fluidization air pipeline, a pressurization air pipeline and a supplementary air pipeline respectively and through them enters an upper discharge bin; a second flue gas pipeline receives the pressurized CO2-rich flue gas and in fluid communication with a gas-gas mixer, a dense phase discharge guide pipe first end extends into the upper discharge bin and receives high-pressure dense phase gas-powder flow of CO2-rich flue gas, and a dense phase discharge guide pipe second end is connected to the gas-gas mixer; a variable-pitch twin screw sealed conveyor discharge end extends into an upper discharge bin internal space, and is provided with an upwardly inclined gas-blocking segment.

Abstract: The disclosure provides IL-7 fusion proteins as well as compositions comprising them. The disclosure further provides methods of treating and/or preventing lymphopenia or immunodeficiency in a subject, wherein the method includes administering a fusion protein as described herein.

Abstract: The invention relates to an improved blast furnace distributing device with a nitrogen sealing structure which belongs to the field of blast furnace. The nitrogen sealing structure is divided into two functional areas on whole structure, wherein a labyrinth structure is arranged at position close to lower side of a blast furnace, which can achieve dustproof and dust falling effects, increase gas pressure resistance loss inside a furnace, and provide favorable conditions for sealing of an upper floating ring; the floating rings which are matched with one another are arranged at position close to upper side of the distributing device can be kept in contact all time through self-adaption in operation process, and achieve tighter combination through mutual running-in, so the structure does not require high-precision manufacturing cost.

Abstract: The present application relates to conduritol aziridines of Formula (I), and uses thereof, for example, of 18F-labelled derivatives thereof in positron-emission tomography (PET) imaging of ?-glucocerebrosidase activity.

Abstract: The present disclosure provides CRISPR-based compositions and methods of their use to impair or promote angiogenesis in a patient to treat indications including, but not limited to, tumor growth, age-related macular degeneration, and metastasis.

Abstract: The present application relates to conduritol aziridines of Formula (I), and uses thereof, for example, of 18F-labelled derivatives thereof in positron-emission tomography (PET) imaging of ?-glucocerebrosidase activity.

Abstract: A planetary transmission device with a small tooth number difference for implementing smart workload self-adaptation comprises a left planetary gear, a right planetary gear, a left-end disk, a right-end disk, a housing and a connection member. One end of the connection member axially run through the left planetary gear and the right planetary gear. End parts of both ends of the connection member are fixedly connected to the left-end disk and the right-end disk respectively. By means of a force closure mechanism, the transmission device can automatically and steplessly adjust a transmission ratio and an output rotation speed according to a change in load without depending on a measurement md control system, md has a simple structure and low costs.

Abstract: The present disclosure provides compositions and methods of their use to impair angiogenesis in a patient to treat indications including, but not limited to, tumor growth, age-related macular degeneration, and metastasis. Also provided are compositions and methods for promoting angiogenesis in patients in need thereof.

Abstract: A planetary transmission device with a small tooth number difference for implementing smart workload self-adaptation comprises a left planetary gear (5), a right planetary gear (2), a left-end disk (4), a right-end disk (1), a housing (3) and a connection member (8). One end of the connection member (8) axially runs through the left planetary gear (5) and the right planetary gear (2). End parts of both ends of the connection member (8) are fixedly connected to the left-end disk (4) and the right-end disk (1) respectively. The left planetary gear (5) is engaged with both the tooth profile on the left-end disk (4) and the tooth profile on the housing (3). The right planetary gear (2) is engaged with the tooth profile on the right-end disk (1) and the tooth profile on the housing (3). The left planetary gear (5), the right planetary gear (2), the left-end disk (4), the right-end disk (1) and the housing (3) form a force closure mechanism.

Abstract: The present disclosure provides compositions and methods of their use to impair angiogenesis in a patient to treat indications including, but not limited to, tumor growth, age-related macular degeneration, and metastasis. Also provided are compositions and methods for promoting angiogenesis in patients in need thereof.

Abstract: The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.

Abstract: The present disclosure describes artemisinin compounds. The compounds can be synthesized using an Ugi synthesis reaction and can be used in the treatment of cancers, parasitic infections and yeast infections.

Abstract: The present disclosure describes artemisinin compounds. The compounds can be synthesized using an Ugi synthesis reaction and can be used in the treatment of cancers, parasitic infections and yeast infections.

Abstract: The present invention relates to the involvement of miR function in the development of age-related macular degeneration (AMD). It is shown that miR-23, miR-24 and/or miR-27 are involved in pathologic neovascularization in AMD, and that agonism (miR-24) and inhibition (miR23/27) of the function of these molecules blocks events contributing to development and progression of disease.

Abstract: The present invention relates to the identification of a microRNA, designated miR-126, that is a regulator of vascular integrity in endothelial cells. This endothelial cell-restricted microRNA mediates developmental angiogenesis in vivo, and targeted deletion of miR-126 in mice causes leaky vessels, hemorrhaging, and partial embryonic lethality, due to a loss of vascular integrity and defects in endothelial cell proliferation, migration, and angiogenesis. These vascular abnormalities resemble the consequences of diminished signaling by angiogenic growth factors, such as VEGF and FGF. These findings have important therapeutic implications for a variety of disorders involving abnormal angiogenesis and vascular leakage. Methods of treating disease states characterized by ischemia, vascular damage, and pathologic neovascularization by modulating miR-126 function are disclosed.