Abstract: A proton beam therapy system 1 includes an irradiation nozzle 25 for irradiating a target 31A with a particle beam, a proton beam irradiation control system 41 that controls the irradiation nozzle 25, a dose monitor 27B that measures an irradiation amount of the particle beam emitted to the target 31A, a position monitor 27A that measures a position of the particle beam emitted to the target 31A, and a dose distribution evaluation system during irradiation 55 that calculates a dose distribution of the particle beam emitted to the target 31A during irradiation. This system supports a medical staff to quickly and appropriately make an intervention determination for treatment such as discontinuation of particle therapy, a change in conditions thereof, or the like in the process of particle irradiation.

Abstract: To enable an appropriate and quick detection of a change in an internal structure of a patient, a computer program causes a computer to detect a change in an internal structure of a patient. The process includes calculating a second water equivalent thickness obtained from a second three-dimensional image being a three-dimensional image of a patient, which is newly obtained; a process of calculating a change of a first water equivalent thickness from the second water equivalent thickness, the first water equivalent thickness being obtained from a first three-dimensional image being a three-dimensional image of the patient in treatment planning; and a process of calculating a dose volume histogram change for calculating a change in a dose volume histogram from the treatment plan, based on the calculated water equivalent thickness change and correlation information indicating a correlation between a water equivalent thickness change value and dose distribution information.

Abstract: A treatment planning apparatus 501 or a clinical decision support apparatus 701 calculates a dose distribution, calculates the damage to a normal tissue for a plurality of number of times of radiation irradiation based on the calculated dose distribution, and displays at least one or more calculated damages to the normal tissues on display apparatuses 603 and 703 or outputs the same to an outside of the apparatuses 501 and 701. Accordingly, since effects can be calculated for a plurality of number of times of irradiation, the optimum number of time of irradiation can be presented, and an operator and a doctor can be presented with a suitable decision material of a radiation irradiation planning.

Abstract: A proton beam therapy system 1 includes an irradiation nozzle 25 for irradiating a target 31A with a particle beam, a proton beam irradiation control system 41 that controls the irradiation nozzle 25, a dose monitor 27B that measures an irradiation amount of the particle beam emitted to the target 31A, a position monitor 27A that measures a position of the particle beam emitted to the target 31A, and a dose distribution evaluation system during irradiation 55 that calculates a dose distribution of the particle beam emitted to the target 31A during irradiation. This system supports a medical staff to quickly and appropriately make an intervention determination for treatment such as discontinuation of particle therapy, a change in conditions thereof, or the like in the process of particle irradiation.

Abstract: A treatment planning apparatus 501 or a clinical decision support apparatus 701 calculates a dose distribution, calculates the damage to a normal tissue for a plurality of number of times of radiation irradiation based on the calculated dose distribution, and displays at least one or more calculated damages to the normal tissues on display apparatuses 603 and 703 or outputs the same to an outside of the apparatuses 501 and 701. Accordingly, since effects can be calculated for a plurality of number of times of irradiation, the optimum number of time of irradiation can be presented, and an operator and a doctor can be presented with a suitable decision material of a radiation irradiation planning.

Abstract: A radiation therapy planning apparatus performs dose calculation at high speed and with high accuracy for radiation therapy in a scanning irradiation method. The apparatus includes a display, an arithmetic processing apparatus, a memory, and a data server, which is connected to a particle beam irradiation apparatus. A dose calculation unit of the arithmetic processing apparatus calculates dose distribution by a simplified Monte Carlo algorithm, and corrects the dose distribution by a decreasing rate stored in a particle number decreasing rate table of the memory, and stores the corrected dose distribution in an integrated dose distribution table. By using the simplified Monte Carlo algorithm and the particle number decreasing rate that corrects the simplified Monte Carlo algorithm, the dose distribution is calculated, and thereby, it is possible to realize a radiation therapy planning apparatus that performs dose calculation at a high speed with high accuracy.

Abstract: A radiation therapy planning apparatus performs dose calculation at high speed and with high accuracy for radiation therapy in a scanning irradiation method. The apparatus includes a display, an arithmetic processing apparatus, a memory, and a data server, which is connected to a particle beam irradiation apparatus. A dose calculation unit of the arithmetic processing apparatus calculates dose distribution by a simplified Monte Carlo algorithm, and corrects the dose distribution by a decreasing rate stored in a particle number decreasing rate table of the memory, and stores the corrected dose distribution in an integrated dose distribution table. By using the simplified Monte Carlo algorithm and the particle number decreasing rate that corrects the simplified Monte Carlo algorithm, the dose distribution is calculated, and thereby, it is possible to realize a radiation therapy planning apparatus that performs dose calculation at a high speed with high accuracy.

Abstract: A spot determination unit classifies an irradiation region to be irradiated with a charged particle beam into a plurality of layers in an irradiation direction of the charged particle beam, and arranges a plurality of irradiation spots in the plurality of layers. The irradiation spots are classified into groups in accordance with at least either a distance between one irradiation spot and another irradiation spot which are arranged in the same layer or a target irradiation dose of each irradiation spot. A plan is prepared for continuously emitting the charged particle beam while the irradiation position is changed from an irradiation spot belonging to a certain group to a subsequent irradiation spot, and so as to stop emitting the charged particle beam while the irradiation position is changed from an irradiation spot belonging to a certain group to an irradiation spot belonging to another group located in the same layer.

Abstract: There is disclosed a radiation treatment planning system for preparing treatment planning information for carrying out radiation treatment. The apparatus includes an input unit with which an operator inputs a prescription dose and an irradiation angle; an arithmetic unit which prepares the treatment planning information by determining irradiation conditions in such a manner as to bring a dose distribution calculated based on the result of the input from the input unit closer to the prescription dose, and a display unit which displays the treatment planning information. The arithmetic unit sets, per point for radiation irradiation, an index representing the degree of demand for irradiation amount suppression, the degree of demand determined by the radiation irradiation point, and the arithmetic unit further determines the irradiation conditions using the index.

Abstract: Optimal irradiation conditions determined by iterative calculation are based upon an operator-defined irradiating direction, prescription dose, and other conditions. Dose matrixes A and B relating doses to calculation points from a beam delivered to irradiating positions are divided into a dose matrix AM or BM for the calculation points in a target region that are present at distances equal to or less than a distance L from the beam axis of the beam delivered to each spot, and a dose matrix AS or BS for the calculation points that are present at distances greater than L. When the iterative calculation is conducted following completion of the division, dose values and {right arrow over (d)}S(1) and {right arrow over (d)}S(2) that include the dose matrixes AS and BS are regarded as constants, and if updating conditions are satisfied, an objective function is recalculated using the values of the dose matrixes A, B and the spot irradiation dose {right arrow over (x)}.

Abstract: There is disclosed a radiation treatment planning system for preparing treatment planning information for carrying out radiation treatment. The apparatus includes an input unit with which an operator inputs a prescription dose and an irradiation angle; an arithmetic unit which prepares the treatment planning information by determining irradiation conditions in such a manner as to bring a dose distribution calculated based on the result of the input from the input unit closer to the prescription dose, and a display unit which displays the treatment planning information. The arithmetic unit sets, per point for radiation irradiation, an index representing the degree of demand for irradiation amount suppression, the degree of demand determined by the radiation irradiation point, and the arithmetic unit further determines the irradiation conditions using the index.

Abstract: Optimal irradiation conditions determined by iterative calculation are based upon an operator-defined irradiating direction, prescription dose, and other conditions. Dose matrixes A and B relating doses to calculation points from a beam delivered to irradiating positions are divided into a dose matrix AM or BM for the calculation points in a target region that are present at distances equal to or less than a distance L from the beam axis of the beam delivered to each spot, and a dose matrix AS or BS for the calculation points that are present at distances greater than L. When the iterative calculation is conducted following completion of the division, dose values and {right arrow over (d)}S(1) and {right arrow over (d)}S(2) that include the dose matrixes AS and BS are regarded as constants, and if updating conditions are satisfied, an objective function is recalculated using the values of the dose matrixes A, B and the spot irradiation dose {right arrow over (x)}.