Patents by Inventor Shuting Yu

Shuting Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047667
    Abstract: The present invention relates to a method for restriction endonuclease-mediated primer generation-rolling circle amplification (PG-RCA), including the following steps of: 1) thiol-modifying a single-stranded DNA (ssDNA) at a restriction site of a restriction endonuclease; 2) cyclizing the thiol-modified ssDNA to obtain a thiol-modified circular ssDNA; and 3) using the thiol-modified circular ssDNA obtained in step 2) as a template, adding the template into a reaction system of a target DNA primer to be detected, a DNA polymerase with strand displacement, and a restriction endonuclease for multiple cycles of rolling circle amplification, to amplify a molecular signal of target DNA.
    Type: Application
    Filed: July 7, 2020
    Publication date: February 18, 2021
    Inventors: Xingguo Liang, Ran An, Chenru Wang, Boying Zhang, Shuting Yu