Patents by Inventor Shuyi Zhang

Shuyi Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220402918
    Abstract: The disclosure relates to an indolo[2?,3?:3,4]pyrido[2,1-b]quinazoline compound represented by general formula (I) and use thereof in the manufacture of (1) a medicament for treating a cardiovascular and cerebrovascular disease, (2) a formulation for increasing expression of AMPK, ABCA1 and SR-BI, (3) a formulation for activating nuclear receptors (NRs), and inhibiting activity of NLRP3, IL-1?, NF-?B and MAPKs, (4) a formulation for promoting cellular cholesterol efflux; or (5) a medicament for anti-inflammation.
    Type: Application
    Filed: September 27, 2020
    Publication date: December 22, 2022
    Inventors: Shuyi SI, Yanni XU, Xiao WANG, Jinque LUO, Yongzhen LI, Chao LIU, Xinhai JIANG, Yining LI, Xiaowan HAN, Yan LI, Minghua CHEN, Jing ZHANG, Xin ZHEN
  • Patent number: 11528791
    Abstract: A driving circuit is provided in this present disclosure, the driving circuit includes a voltage input module, a quick start module and a control module. The voltage input module includes a first input terminal and a second input terminal and is configured to receive an alternating current voltage and convert the alternating current voltage into a direct current voltage. The quick start module is coupled to the voltage input module and configured to receive the direct current voltage and convert the direct current voltage into a startup voltage. The control module is coupled to the quick start module and configured to receive the startup voltage and control a load, wherein the quick start module comprises a first resistor and a second resistor connected in series and is coupled between the first input terminal and the control module.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: December 13, 2022
    Assignee: CURRENT LIGHTING SOLUTIONS, LLC
    Inventors: Zhu Mao, Min Fang, Zhangji Zhou, Shuyi Qin, Bo Zhang, Fanbin Wang
  • Patent number: 11515155
    Abstract: Methods of improved selectively for SAM-based selective depositions are described. Some of the methods include forming a SAM on a second surface and a carbonized layer on the first surface. The substrate is exposed to an oxygenating agent to remove the carbonized layer from the first surface, and a film is deposited on the first surface over the protected second surface. Some of the methods include overdosing a SAM molecule to form a SAM layer and SAM agglomerates, depositing a film, removing the agglomerates, reforming the SAM layer and redepositing the film.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: November 29, 2022
    Assignee: APPLIED MATERIALS, INC.
    Inventors: Chang Ke, Michael S. Jackson, Liqi Wu, Lei Zhou, Shuyi Zhang, David Thompson, Paul F. Ma, Biao Liu, Cheng Pan
  • Patent number: 11478935
    Abstract: A method for a robot to automatically find a bending position, including the following steps: step 1, establishing a gripper tool coordinate system (TX, TY, TZ); step 2, determining a user coordinate system (XA, YA, ZA; XB, YB, ZB) of rear blocking fingers (11, 21); step 3, a robot gripper moving horizontally, and detecting the state of sensors (12, 22); step 4, the robot gripper executing a rotational movement, detecting the state of the sensors (12, 22), and thereby obtaining a standard bending position. The robot automatically finds the bending position, the teaching difficulty is reduced, and the bending quality is increased. In the elevator industry, elevator door plate bending sizes are the same, but forming sizes are different. In the present invention, only one product process needs to be taught in order to satisfy elevator door plate processing with different specifications, thereby reducing maintenance costs and increasing production efficiency.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: October 25, 2022
    Assignee: NANJING ESTUN ROBOTICS CO., LTD
    Inventors: Jinbao Zhang, Lin Zhou, Shuyi Jing, Xiaobo Chi, Jiegao Wang
  • Patent number: 11443237
    Abstract: Systems and techniques are disclosed for a centralized platform for enhanced automated machine learning using disparate datasets. An example method includes receiving user specification of one or more data sources to be integrated with the system, the data sources storing datasets to be utilized to train one or more machine learning models by the system, and the datasets reflecting user interaction data. A dataset is imported from the data source, and machine learning models are automatically trained based a particular machine learning model recipe of a plurality of machine learning model recipes. A first trained machine learning model is implemented, with the system being configured to respond to queries based on the implemented machine learning model, and with the responses including personalized recommendations.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: September 13, 2022
    Assignee: Amazon Technologies, Inc.
    Inventors: Hyunjoon Song, Bindu Priya Reddy, Shuyi Zhang, Venkatesh Maralavadi Sreenivas, Madan Mohan Rao Jampani, Stefano Stefani
  • Publication number: 20210217615
    Abstract: Methods of improved selectively for SAM-based selective depositions are described. Some of the methods include forming a SAM on a second surface and a carbonized layer on the first surface. The substrate is exposed to an oxygenating agent to remove the carbonized layer from the first surface, and a film is deposited on the first surface over the protected second surface. Some of the methods include overdosing a SAM molecule to form a SAM layer and SAM agglomerates, depositing a film, removing the agglomerates, reforming the SAM layer and redepositing the film.
    Type: Application
    Filed: March 10, 2021
    Publication date: July 15, 2021
    Applicant: Applied Materials, Inc.
    Inventors: Chang Ke, Michael S. Jackson, Liqi Wu, Lei Zhou, Shuyi Zhang, David Thompson, Paul F. Ma, Biao Liu, Cheng Pan
  • Publication number: 20210079404
    Abstract: Disclosed herein are novel CRISPR/dCas9-based fusion proteins that facilitate the scaling up of genetic circuits, including those with non-linear response curves. The dCas9 based fusion proteins produce significantly less toxicity in comparison to previously described CRISPR/Cas9-based proteins used with logic gates. These improvements enable the generation of complex genetic circuits when both digital response curves and large amounts of dCas9 protein are needed. Also disclosed herein are methods of regulating expression of an output sequence through the introduction of novel CRISPR/dCas-9-based fusion proteins and genetic circuits into a cell.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 18, 2021
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Shuyi Zhang
  • Patent number: 10950433
    Abstract: Methods of improved selectively for SAM-based selective depositions are described. Some of the methods include forming a SAM on a second surface and a carbonized layer on the first surface. The substrate is exposed to an oxygenating agent to remove the carbonized layer from the first surface, and a film is deposited on the first surface over the protected second surface. Some of the methods include overdosing a SAM molecule to form a SAM layer and SAM agglomerates, depositing a film, removing the agglomerates, reforming the SAM layer and redepositing the film.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: March 16, 2021
    Assignee: APPLIED MATERIALS, INC.
    Inventors: Chang Ke, Michael S. Jackson, Liqi Wu, Lei Zhou, Shuyi Zhang, David Thompson, Paul F. Ma, Biao Liu, Cheng Pan
  • Publication number: 20200095589
    Abstract: Disclosed herein are novel CRISPR/dCas9-based fusion proteins that facilitate the scaling up of genetic circuits, including those with non-linear response curves. The dCas9 based fusion proteins produce significantly less toxicity in comparison to previously described CRISPR/Cas9-based proteins used with logic gates. These improvements enable the generation of complex genetic circuits when both digital response curves and large amounts of dCas9 protein are needed. Also disclosed herein are methods of regulating expression of an output sequence through the introduction of novel CRISPR/dCas-9-based fusion proteins and genetic circuits into a cell.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 26, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Shuyi Zhang
  • Publication number: 20190157079
    Abstract: Methods of improved selectively for SAM-based selective depositions are described. Some of the methods include forming a SAM on a second surface and a carbonized layer on the first surface. The substrate is exposed to an oxygenating agent to remove the carbonized layer from the first surface, and a film is deposited on the first surface over the protected second surface. Some of the methods include overdosing a SAM molecule to form a SAM layer and SAM agglomerates, depositing a film, removing the agglomerates, reforming the SAM layer and redepositing the film.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 23, 2019
    Inventors: Chang Ke, Michael S. Jackson, Liqi Wu, Lei Zhou, Shuyi Zhang, David Thompson, Paul F. Ma, Biao Liu, Cheng Pan
  • Publication number: 20160226930
    Abstract: In one embodiment a user interface for a communication device is described, the user interface including a first icon representing a first communication event between a first party and a second party, and a second icon representing a second communication event between the first party and a third party, a processor to receive input signals from the first party, the signals input via the user interface, the processor, in response to the received input signals, performs one of a communication event transfer including transferring the first communication event from being between the first party and the second party to being between the second party and the third party, and a communication event merger including the creation of a merged communication event between the user, the second party, and the third party. Related methods, systems, and apparatuses are also described.
    Type: Application
    Filed: January 29, 2015
    Publication date: August 4, 2016
    Inventors: Shuyi ZHANG, Junhua MA, XiuYing ZHANG, Chongni LI
  • Patent number: 9116300
    Abstract: Technologies are generally described for techniques useful in an interferometer system. In some examples, a system may include a first waveguide effective to propagate a first wave in a first mode. In some examples, the system may include a second waveguide effective to, in response to the first wave, propagate second and third waves in second and third modes, respectively. In some examples, the second waveguide may be effective to reflect the second and third waves off a reflection surface to produce first, second, third and fourth reflected waves. In some examples, the second waveguide may be effective to propagate the first and third reflected waves in the second mode and propagate the second and fourth reflected waves in the third mode.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: August 25, 2015
    Assignee: Nanjing University
    Inventors: Yanqing Lu, Shuyi Zhang, Qi Zhong, Fei Xu, Xiaowen Lin, Wei Hu
  • Patent number: 8519168
    Abstract: This application discloses a novel process for the preparation of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds, which have utility, for example, in the treatment of CXC chemokine-mediated diseases, and intermediates useful in the synthesis thereof.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: August 27, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Xiaoyong Fu, Frank Bruno Guenter, Agnes S. Kim-Meade, Kenneth Stanley Matthews, Mathew Thomas Maust, Gerald Werne, Jason L. Winters, Jianguo Yin, Shuyi Zhang, David J. Moloznik
  • Publication number: 20120224806
    Abstract: Technologies are generally described for techniques useful in an interferometer system. In some examples, a system may include a first waveguide effective to propagate a first wave in a first mode. In some examples, the system may include a second waveguide effective to, in response to the first wave, propagate second and third waves in second and third modes, respectively. In some examples, the second waveguide may be effective to reflect the second and third waves off a reflection surface to produce first, second, third and fourth reflected waves. In some examples, the second waveguide may be effective to propagate the first and third reflected waves in the second mode and propagate the second and fourth reflected waves in the third mode.
    Type: Application
    Filed: June 25, 2010
    Publication date: September 6, 2012
    Applicant: Nanjing University
    Inventors: Yanqing Lu, Shuyi Zhang, Qi Zhong, Fei Xu, Xiaowen Lin, Wei Hu
  • Patent number: 8207221
    Abstract: The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure: These four polymorphic forms, herein referred to as Forms I, II, III and IV are active as a CXC-chemokine receptor ligands. The invention is further directed to formulations, methods of treatment, and processes of synthesis of these polymorphic forms.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: June 26, 2012
    Assignee: Schering Corporation
    Inventors: Mengwei Hu, Younong Yu, Michael P. Dwyer, Arthur G. Taveras, Agnes Kim-Meade, Jianguo Yin, Xiaoyong Fu, Timothy L. McAllister, Shuyi Zhang, Kevin Klopfer
  • Patent number: 7985860
    Abstract: This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: July 26, 2011
    Assignee: Schering Corporation
    Inventors: Timothy D. Cutarelli, Xiaoyong Fu, Timothy L. McAllister, Michael R. Reeder, Jianguo Yin, Kelvin H. Yong, Shuyi Zhang
  • Patent number: 7910775
    Abstract: Disclosed is a process for making the compound of formula I: using the compounds of formulas II, Q, and XI or XII: wherein A is selected from the group consisting of Br, Cl and I (with Br being preferred); and R represents (C1-C10)alkyl. Also disclosed are intermediate compounds that are made in the disclosed process.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: March 22, 2011
    Assignee: Schering Corporation
    Inventors: Jianguo Yin, Xiaoyong Fu, Shuyi Zhang, Timothy L. McAllister, Agnes S. Kim-Meade, Jason L. Winters, Anantha Sudhakar, Doris P. Schumacher
  • Publication number: 20090162431
    Abstract: The present invention provides a pharmaceutical dosage form for sustained release of a combination of acetaminophen and tramadol or its salts. The dosage form has an immediate release portion and a sustained release portion. The immediate release portion has about 16%-75% of the drugs. The sustained release portion includes: a. about 25%-84% of the drugs, at least one gelling polymer in an amount by weight of the total formulation of about 6% to 50%. The dosage form releases about 25% to about 60% of the drugs in the first hour, and not less than about 80% of the drugs in the first 24 hours in an intestinal fluid dissolution media using USP dissolution method II with the paddle speed between 50 rpm and 100 rpm.
    Type: Application
    Filed: May 19, 2008
    Publication date: June 25, 2009
    Inventors: Shuyi Zhang, Jin Wang, Shaoling Li
  • Publication number: 20090048458
    Abstract: Disclosed is a process for making the compound of formula I: using the compounds of formulas II, Q, and XI or XII: wherein A is selected from the group consisting of Br, Cl and I (with Br being preferred); and R represents (C1-C10)alkyl. Also disclosed are intermediate compounds that are made in the disclosed process.
    Type: Application
    Filed: October 17, 2008
    Publication date: February 19, 2009
    Inventors: Jianguo Yin, Xiaoyong FU, Shuyi Zhang, Timothy L. McAllister, Agnes S. Kim-Meade, Jason L. Winters, Anantha Sudhakar, Doris P. Schumacher
  • Patent number: 7462740
    Abstract: Disclosed is a process for making the compound of formula I: using the compounds of formulas II, Q, and XI or XII: wherein A is selected from the group consisting of Br, Cl and I (with Br being preferred); and R represents (C1-C10)alkyl. Also disclosed are intermediate compounds that are made in the disclosed process.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: December 9, 2008
    Assignee: Schering Corporation
    Inventors: Jianguo Yin, Xiaoyong Fu, Shuyi Zhang, Timothy L. McAllister, Agnes S. Kim-Meade, Jason L. Winters, Anantha Sudhakar, Doris P. Schumacher