Patents by Inventor Shuyu WEN

Shuyu WEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DECELLULARIZED HEART VALVE (DHV) COMPOSITE, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20240226379
    Abstract: Some embodiments of the disclosure provide a decellularized heart valve (DHV) composite, a preparation method of the DHV composite, and a use of the DHV composite. In some examples, the preparation method of the DHV composite includes the following steps: S1, conducting a reaction I on a DHV with a copper chloride-dopamine hydrochloride mixed solution to obtain a copper ion-modified DHV; and S2, conducting a reaction II on the copper ion-modified DHV with a GDF11 solution to obtain the DHV composite. In other examples, the present disclosure provides a use of the DHV composite in preparation of a tissue-engineered heart valve (TEHV). In further examples, the TEHV is a heart valve (HV) with remodeling and regeneration capabilities.
    Type: Application
    Filed: August 3, 2023
    Publication date: July 11, 2024
    Applicant: UNION HOSPITAL TONGJI MEDICAL COLLEGE HUST
    Inventors: Nianguo DONG, Ying ZHOU, Weihua QIAO, Ge YAN, Shuyu WEN, Xing CHEN
  • DECELLULARIZED HEART VALVE (DHV) COMPOSITE, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20240131223
    Abstract: Some embodiments of the disclosure provide a decellularized heart valve (DHV) composite, a preparation method of the DHV composite, and a use of the DHV composite. In some examples, the preparation method of the DHV composite includes the following steps: S1, conducting a reaction I on a DHV with a copper chloride-dopamine hydrochloride mixed solution to obtain a copper ion-modified DHV; and S2, conducting a reaction II on the copper ion-modified DHV with a GDF11 solution to obtain the DHV composite. In other examples, the present disclosure provides a use of the DHV composite in preparation of a tissue-engineered heart valve (TEHV). In further examples, the TEHV is a heart valve (HV) with remodeling and regeneration capabilities.
    Type: Application
    Filed: August 2, 2023
    Publication date: April 25, 2024
    Applicant: UNION HOSPITAL TONGJI MEDICAL COLLEGE HUST
    Inventors: Nianguo DONG, Ying ZHOU, Weihua QIAO, Ge YAN, Shuyu WEN, Xing CHEN