Abstract: The present disclosure relates to use of a compound in preparation of a medicament for prophylaxis and treatment of inflammatory tissue damage. The present disclosure provides use of a compound in preparation of a medicament for prophylaxis and treatment of tissue damage, and the compound has a structure represented by formula I. The compound having the structure represented by formula I provided by the present disclosure can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1), have prophylactic and therapeutic effects on tissue damage, enhance cell proliferation ability after tissue cell injury, and repair injured tissues. The compound having the structure represented by formula I provided by the present disclosure has important significance and application value in the preparation of the medicament for prophylaxis and treatment of tissue damage, particularly in the preparation of a medicament for inflammatory injuries of skin tissues induced by radiation and/or oxidation.

Abstract: A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member and a central bar member. The bow-shaped frame member is characterized by a higher coefficient of thermal expansion than that of the central bar member such that the bow-shaped frame member can expand and contract at variable rates compared to that of the central bar member under certain temperature conditions. The bow-shaped frame member is adapted to be attached to a movable section of an athermal arrayed waveguide grating (AAWG) module such that the expansion and contraction movements of the bow-shaped member influence the movement of a movable section of the AAWG module in order to maintain the proper focus of the AAWG module across disparate temperature conditions.

Abstract: A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member.

Abstract: A comprehensive evaluation method of military training level includes: selecting evaluation indicators of military training level, and establishing an evaluation indicator system of military training level by a multi-tree structure; constructing a leaf node evaluation indicator fusion model including a time indicator fusion model and a quality indicator fusion model, and performing multi-source data fusion processing on leaf node indicator data through the leaf node evaluation indicator fusion model; constructing a leaf node evaluation indicator model of military training level; constructing a parent node evaluation indicator model of military training level based on weight information of evaluation indicators of military training level of nodes in the multi-tree structure; and constructing a total indicator evaluation model by a method of breadth first search of multi-tree to complete the comprehensive evaluation of military training level.

Abstract: A thermal compensator, for use in connection with arrayed waveguide grating (AWG) modules which are, in turn, utilized in conjunction with wavelength multiplexing and de-multiplexing within optical networks, is disclosed. The thermal compensator comprises a bow-shaped frame member, a central bar member, and a screw. The bow-shaped frame member is characterized by a higher or great coefficient of thermal expansion (CTE) than that of the central bar member such that the bow-shaped frame member can expand and elongate at a greater rate than can the central bar member under hot temperature conditions, however, under cold temperature conditions, the rate of contraction of the bow-shaped member is effectively retarded by the slower rate of contraction of the central bar member.

Abstract: A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

Abstract: The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.

Abstract: A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

Abstract: A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

Abstract: The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.

Abstract: The invention relates to a transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1. The invention provides a fusion protein with a nuclear localization ability, which comprises a macromolecular protein with one end being linked to the transdermal peptide. The invention also discloses the use of the transdermal peptide in the preparation of a medicament or a transdermal preparation for treating skin diseases. The invention further provides a medicament for treating a skin disease, comprising the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.

Abstract: A disk drive is provided having one or more structural air bearing surface (ABS) features that can block particulate matter, such as lube droplets that may enter the air bearing from the trailing edge or rearward portion of the slider. Moreover, such structural ABS features can influence air flow within or about the air bearing to prevent or at least reduce the accumulation of particles and/or droplets in one or more areas of the air bearing to reduce the reliability problems induced by particle contamination and lube pick-up.

Abstract: A disk drive for redirecting contaminating particulate matter away from an area bearing of a slider element. At least two etched channels are provided in the slider element of the disk drive. The at least two etched channels direct incoming air flow to a leading edge of the slider element from the leading edge towards respective sides of the slider element. Particulate matter that may be progressing towards the air bearing are redirected by virtue of the incoming air flow to the leading edge and expelled from the air bearing via the at least two etched channels.

Abstract: A disk drive is provided having a dynamic flying height or touch down power profile that is substantially flat across its stroke along the radius of a recording medium. At least two air-channeling elements are provided in a slider of the disk drive, that with the read/write head, flies above a surface of the recording medium. At an inner diameter and an outer diameter of the recording medium, the at least two air-channeling elements direct incoming air flow to an air bearing space defined by a bottom surface of the slider and the surface of the recording medium, increasing the flying height of the slider/read/write head at the inner diameter and outer diameter of the recording medium, thereby negating the effect of a middle diameter flying height hump of the recording medium.

Abstract: A slider including air bearing surface with Flying height On-Demand (FOD) protrusion with method of controlling airflow to maximize FOD efficiency as ratio of change in vertical position to protrusion height. Slider including components controlling the air flow to maximize FOD efficiency and/or including specific components minimizing an air bearing pressure under a Flying height On Demand (FOD) operation away from a maximum air bearing pressure, placing a peak pressure off of an FOD area create by a FOD protrusion, and shrinking a high peak pressure area of the air bearing surface. Hard disk drive includes head stack assembly, which includes head gimbal assembly, which includes the slider. Manufacturing method for slider, head gimbal assembly, head stack assembly and hard disk drive, and these items as products of these processes.

Abstract: A slider that includes a necked ABS pad is disclosed. More specifically, the slider includes an ABS pad having a first ABS region and a second ABS region, where the second ABS region is disposed immediately in front of the first ABS region proceeding in the direction of a leading edge of the slider. A transducer and a thermal actuator each may be disposed within the first ABS region. The width of the second ABS region (a necked portion of the ABS pad) is less than a width of the first ABS region.

Abstract: A slider operating air bearing surface (ABS) to remove a front saturation water vapor pressure peak near a front bulwark and a bad flow pattern area the between front bulwark and a central island. The ABS implementing these operations. Alternatively, ABS includes a front bulwark channel in the front bulwark and a central fin between the front bulwark and the central island. Slider includes an embodiment of the ABS. Head gimbal assembly (HGA) includes the slider. Head stack assembly includes at least one HGA. Hard disk drive includes the head stack assembly. Manufacturing methods for the slider, the HGA, the head stack assembly, the hard disk drive, and these items as products of their manufacturing processes.

Abstract: Hard disk drive (HDD) including humidity sensor measuring interior and second humidity sensor measuring exterior with door actuator controlling door for mass transfer between interior and exterior based upon determination of whether or not to transfer. HDD may further include and use temperature sensors for interior and/or exterior to further control door. An embedded circuit and processor at least partly implementing these operations. External cover including door and door actuator, possibly second sensors. Manufacturing methods and these items as their products.

Abstract: A disk drive for storing data includes a rotating storage disk and a slider positioned near the storage disk. The slider has a flying side and a read/write head. The flying side includes a leading bearing surface and a leading recessed surface positioned near a leading edge of the slider. The leading bearing surface can include a leading transverse section that is positioned within approximately 20 and 200 microns of the leading edge. The leading recessed surface is positioned between the leading transverse section and the leading edge. The leading bearing surface and the leading recessed surface cooperate to form a relatively high pressure area near the leading edge that facilitates a relatively rapid take-off of the slider away from the storage disk during start up of the disk drive.

Abstract: Estimating methods and apparatus are disclosed for the patterned flying height of an air bearing surface over a patterned surface from the flying height over a smooth surface minus a flying height delta based upon the patterned surface. A hard disk drive is disclosed including the air bearing surface over a rotating disk surface that at least partly includes a patterned surface. A slider with the air bearing surface is disclosed for use over the patterned disk surface. Also disclosed: a head gimbal assembly including the slider and a head stack assembly coupling through the head gimbal assembly to position the slider.