Abstract: Provided is an efficient preparation method of a bimetallic seamless composite pipe, and belongs to the technical field of steel pipe manufacture. The efficient preparation method of the bimetallic seamless composite pipe includes following steps: sheathing a base pipe blank on a cladding pipe blank to obtain a composite pipe blank, and carrying out a stress relief annealing treatment on the composite pipe blank, where the base pipe blank and the cladding pipe blank are made of different materials; heating the composite pipe blank after the stress relief annealing treatment to a hot working window temperature, and sheathing on a core rod of an extrusion cylinder after an insulation treatment, and then extruding along an axial direction of the extrusion cylinder to obtain a bimetallic seamless composite pipe.