Patents by Inventor Shwu-Chen Tsay
Shwu-Chen Tsay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7976876Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and a quinone, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: September 29, 2008Date of Patent: July 12, 2011Assignee: Well-Being Biochemical Corp.Inventors: Jih-ru Hwu, Shwu-chen Tsay
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Patent number: 7858124Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: April 7, 2008Date of Patent: December 28, 2010Assignee: Well-Being Biochemical Corp.Inventors: Jih Ru Hwu, Shwu Chen Tsay
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Patent number: 7585826Abstract: This invention relates to compositions that counteract chemicals such as pesticides and malodorants. Also disclosed are a method for preparing such compositions and a method for applying such compositions to counteract pesticides or malordorants.Type: GrantFiled: March 22, 2007Date of Patent: September 8, 2009Assignee: Well-Being Biochemical Corp.Inventors: Jih-Ru Hwu, Shwu-Chen Tsay
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Publication number: 20090098098Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and quinones, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: ApplicationFiled: September 29, 2008Publication date: April 16, 2009Applicant: Well-Being Biochemical Corp.Inventors: Jih-Ru Hwu, Shwu-Chen Tsay
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Publication number: 20080254141Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: ApplicationFiled: April 7, 2008Publication date: October 16, 2008Applicant: Well-Being biochemical Corp.Inventors: Jih-ru Hwu, Shwu-chen Tsay
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Publication number: 20080234158Abstract: This invention relates to compositions that counteract chemicals such as pesticides and malodorants. Also disclosed are a method for preparing such compositions and a method for applying such compositions to counteract pesticides or malordorants.Type: ApplicationFiled: March 22, 2007Publication date: September 25, 2008Inventors: Jih Ru Hwu, Shwu-Chen Tsay
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Patent number: 7387799Abstract: The present invention relates to an anti-bacterial, anti-viral, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: July 29, 2003Date of Patent: June 17, 2008Assignee: Well-Being Biochemical Corp.Inventors: Jih-Ru Hwu, Shwu-Chen Tsay
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Patent number: 7282606Abstract: The present invention discloses a new process for the synthesis of tamsulosin and its aralkylamine derivatives, especially (R)-(?)-5-{2-[2-(2-alkoxyphenoxy) ethylamino]propyl}-2-alkoxybenzenesulfonamides having the following formula 1 (where R1 and R2 represent C1-C4 alkyl groups) and their hydrochloride thereof, and other various pharmaceutical used salts. Tamsulosin hydrochloride (R1=Et, R2=Me, in its hydrochloride salt form) is an antagonist of ?-A adrenoceptors in the prostate. Tamsulosin•HCl occurs as white crystals, which melt with decomposition at approximately 230° C. It is sparingly soluble in water and in methanol, slightly soluble in glacial acetic acid and in ethanol, and practically insoluble in ether.Type: GrantFiled: July 13, 2005Date of Patent: October 16, 2007Assignees: Well-Being Biochemical Corp., Taiwan Biotech Co., Ltd.Inventors: Ru Hwu Jih, Shwu Chen Tsay, Balaachary Magendran, Subhasish K. Chakraborty, Asish R. Das, Kuen Wang Sheu, Chun Mei Shu, Chin Kun Lu, Wei Min Chang
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Publication number: 20070152569Abstract: The present invention relates to novel benzo[b]furan derivatives, particular to novel benzo[b]furan derivatives having substituents at the 4-position. The present invention also relates to a use of the benzo[b]furan derivatives as electroluminescent material in OLED.Type: ApplicationFiled: January 4, 2006Publication date: July 5, 2007Inventors: Jih-Ru Hwu, Shwu-Chen Tsay, Kao-Shuh Chuang
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Publication number: 20060246148Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and an agent having oxidizing ability; and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: ApplicationFiled: February 1, 2006Publication date: November 2, 2006Inventors: Jih-Ru Hwu, Shwu-Chen Tsay
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Patent number: 6812247Abstract: A metal complex and its use for binding or cleaving a nucleic acid. The metal complex has the formula: M is Pt, Pd, Ni, Co, or Cu; X is aryl, heteroaryl, cyclyl, or heterocyclyl; Y is halogen, tosylate, mesylate, triflate, pyrophosphate, or carboxylate; each of A1 and A2, independently, is N or C; each of A3 and A4, independently, is N, S, or O, wherein A1, A2, A3, and A4 taken together have one positive charge; and each of R1 and R2, independently, is alkyl, aryl, heteroaryl, alkoxyl, aryloxyl, heteroaryloxyl, alkoxylcarbonyl, aryloxylcarbonyl, or heteroaryloxylcarbonyl.Type: GrantFiled: September 30, 2002Date of Patent: November 2, 2004Assignee: Academia SinicaInventors: Kuang-Lieh Lu, Jih-Ru Hwu, Shwu-Chen Tsay, Sheng-Fa Yu, Jui-Te Hung, Jiann-Jyh Huang
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Publication number: 20030105068Abstract: A metal complex and its use for binding or cleaving a nucleic acid.Type: ApplicationFiled: September 30, 2002Publication date: June 5, 2003Inventors: Kuang-Lieh Lu, Jih-Ru Hwu, Shwu-Chen Tsay, Sheng-Fa Yu, Jui-Te Hung, Jiann-Jyh Huang
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Patent number: 6458833Abstract: A metal complex and its use for binding or cleaving a nucleic acid. The metal complex has the formula: M is Pt, Pd, Ni, Co, or Cu; X is aryl, heteroaryl, cyclyl, or heterocyclyl; Y is halogen, tosylate, mesylate, triflate, pyrophosphate, or carboxylate; each of A1 and A2, independently, is N or C; each of A3 and A4, independently, is N, S, or 0, wherein A1, A2, A3, and A4 taken together have one positive charge; and each of R1 and R2, independently, is alkyl, aryl, heteroaryl, alkoxyl, aryloxyl, heteroaryloxyl, alkoxylcarbonyl, aryloxylcarbonyl, or heteroaryloxylcarbonyl.Type: GrantFiled: November 20, 2001Date of Patent: October 1, 2002Assignee: Academia SinicaInventors: Kuang-Lieh Lu, Jih-Ru Hwu, Shwu-Chen Tsay, Sheng-Fa Yu, Jui-Te Hung, Jiann-Jyh Huang
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Syntheses of new isodethiaazacephems and isodethiaazacephams, and use as potent antibacterial agents
Patent number: 6348454Abstract: An isodethiaazacephem derivative having the following formula (I): wherein RI is hydrogen or —SO2RIII; RII is —CO2RIV or —SO2RIII in which RIII is a hydrogen, C1-C6 alkyl, aralkyl having a total carbon number of 7-12, aryl, or a halogenated C1-C6 alkyl; and RIV is a hydrogen, C1-C6 alkyl, aralkyl having a total carbon number of 7-12 or aryl; and RV is a substituted acetamido radical.Type: GrantFiled: May 12, 1999Date of Patent: February 19, 2002Assignee: National Science CouncilInventors: Jih Ru Hwu, Shwu-Chen Tsay, Shahram Hakimelahi -
Patent number: 6288265Abstract: A series of phloroglucide derivatives are synthesized, which possess potent antibacterial activities. They include unsymmetrical phloroglucide analogs, phloroglucides attached to cephalosporins at the C-3′ position, and 7-(phloroglucidamido)cephalosporins.Type: GrantFiled: September 20, 1999Date of Patent: September 11, 2001Assignee: National Science CouncilInventors: Jih Ru Hwu, Shwu-Chen Tsay, Gholam H. Hakimelahi, Chun Chieh Lin, Wen Nan Tseng, Ali A. Moshfegh, Abdolmajid Azaripour, Hasan Mottaghian
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Patent number: 6121255Abstract: A phloroglucide derivative having the following formula: ##STR1## wherein Q is halogen; X is CH.sub.2 or C.dbd.O; Y is cephalosporin having a formula of ##STR2## wherein Ph is phenyl, Ac is acetoxy, or pharmaceutically acceptable salts thereof, and an antibacterial pharmaceutical composition derived thereof.Type: GrantFiled: May 4, 1998Date of Patent: September 19, 2000Assignee: National Science CouncilInventors: Jih Ru Hwu, Shwu-Chen Tsay, Gholam H. Hakimelahi, Chun Chieh Lin, Wen Nan Tseng, Ali A. Moshfegh, Abdolmajid Azaripour, Hasan Mottaghian
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Patent number: 5760013Abstract: Novel thymidylate analogs having the following formula are synthesized in the present invention, which are found active against human immunodeficiency virus type 1 (HIV-1): ##STR1## wherein R.sup.1 is hydrogen, cyano (--CN), halogen or azido (--N.sub.3); R.sup.2 is hydroxyl or an amino ester radical having a formula of --NHR.sup.4 COOR.sup.5, wherein R.sup.4 is a bivalent C.sub.1 -C.sub.4 saturated hydrocarbon and R.sup.5 is C.sub.1 -C.sub.4 alkyl; Me is methyl; and R.sup.Type: GrantFiled: August 21, 1996Date of Patent: June 2, 1998Assignee: National Science CouncilInventors: Jih Ru Hwu, Gholam H. Hakimelahi, Shwu-Chen Tsay
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Patent number: 5734032Abstract: The present invention discloses a photo-induced DNA-cleaving agent composition comprises N-aryl-N-(alkyl or arylalkyl)hydroxylamine having the following formula: ##STR1## wherein R is C.sub.1 -C.sub.6 alkyl, phenyl, C.sub.1 -C.sub.6 alkoxy, phenoxy, C.sub.1 -C.sub.6 alkoxycarbonyl, halogen or halo(C.sub.1 -C.sub.6 alkyl)wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkoxycarbonyl, halogen or halo(C.sub.1 -C.sub.6 alkyl); R.sub.2 is hydrogen; R.sub.3 is hydrogen or phenyl; R.sub.4 is hydrogen, phenyl, hydroxylphenyl, methoxyphenyl, dimethoxyphenyl, dimethylaminophenyl or naphthyl. The present N-aryl-N-(alkyl or arylalkyl)hydroxylamine is stable in dark, but it can react with O.sub.2 to form HO.multidot. radicals under irradiation of UV light for a period of 2-3 hours. The HO.multidot. radicals then react with DNA to accomplish cleavage of DNA.Type: GrantFiled: December 29, 1995Date of Patent: March 31, 1998Assignee: National Science CouncilInventors: Jih Ru Hwu, Shwu-Chen Tsay, Buh-Luen Chen, Himatkumar V. Patel, Wan-Lin Chen, Chun Chieh Lin, Ching-Tai Chou
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Patent number: 5733890Abstract: Novel adenylate analogs having the following formula are synthesized in the present invention, which are found active against herpes simplex viruses: ##STR1## wherein R.sup.1 is hydroxyl, C.sub.1 -C.sub.4 alkoxy, an amino ester radical of --NHR.sup.3 COOR.sup.4, wherein R.sup.3 is a bivalent C.sub.1 -C.sub.4 saturated hydrocarbon and R.sup.4 is C.sub.1 -C.sub.4 alkyl; and R.sup.2 is hydroxyl, --O.sup.+ NH.sub.Type: GrantFiled: October 9, 1996Date of Patent: March 31, 1998Assignee: National Science CouncilInventors: Jih Ru Hwu, Gholam H. Hakimelahi, Shwu-Chen Tsay, Ali A. Moosavi-Movahedi, Majid M. Sadeghi
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Patent number: 5527683Abstract: The present invention discloses a photo-induced DNA-cleaving agent composition comprises N-aryl-N-(alkyl or arylalkyl)hydroxylamine having the following formula: ##STR1## wherein R is C.sub.1 -C.sub.6 alkyl, phenyl, C.sub.1 -C.sub.6 alkoxy, phenoxy, C.sub.1 -C.sub.6 alkoxycarbonyl, halogen or halo(C.sub.1 -C.sub.6 alkyl)wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkoxycarbonyl, halogen or halo(C.sub.1 -C.sub.6 alkyl); R.sub.2 is hydrogen; R.sub.3 is hydrogen or phenyl; R.sub.4 is hydrogen, phenyl, hydroxylphenyl, methoxyphenyl, dimethoxyphenyl, dimethylaminophenyl or naphthyl. The present N-aryl-N-(alkyl or arylalkyl)hydroxylamine is stable in dark, but it can react with O.sub.2 to form HO. radicals under irradiation of UV light for a period of 2-3 hours. The HO. radicals then react with DNA to accomplish cleavage of DNA.Type: GrantFiled: March 20, 1995Date of Patent: June 18, 1996Assignee: National Science CouncilInventors: Jih R. Hwu, Shwu-Chen Tsay, Buh-Luen Chen, Himatkumar V. Patel, Wan-Lin Chen, Chun C. Lin, Ching-Tai Chou