Patents by Inventor Shyam Ramchandani

Shyam Ramchandani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA demethylase, therapeutic and diagnostic uses thereof
    Patent number: 7098012
    Abstract: The present invention relates to a DNA demethylase enzyme having about 40 KDa, and wherein said DNA demethylase enzyme is overexpressed in cancer cells and not in normal cells. The present invention also relates to the therapeutic and diagnostic uses of the DNA demethylase.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: August 29, 2006
    Assignee: McGill University
    Inventors: Moshe Szyf, Sanjoy Bhattacharya, Shyam Ramchandani
  • DNA methyltransferase genomic sequences and antisense oligonucleotides
    Patent number: 6221849
    Abstract: The invention provides recombinant nucleic acids comprising nucleic acid sequences from the genomic DNA methyltransferase gene. The invention further provides sequence information for such nucleic acid sequences. In addition, the invention provides antisense oligonucleotides complementary to special regions of the genomic DNA methyltransferase gene or its RNA transcript. Finally, the invention provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.
    Type: Grant
    Filed: June 24, 1998
    Date of Patent: April 24, 2001
    Assignee: MethylGene, Inc.
    Inventors: Moshe Szyf, Pascal Bigey, Shyam Ramchandani
  • DNA methyltransferase genomic sequences and antisense oligonucleotides
    Patent number: 6020318
    Abstract: The invention provides recombinant nucleic acids comprising nucleic acid sequences from the genomic DNA methyltransferase gene. The invention further provides sequence information for such nucleic acid sequences. In addition, the invention provides antisense oligonucleotides complementary to special regions of the genomic DNA methyltransferase gene or its RNA transcript. Finally, the invention provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: February 1, 2000
    Assignee: MethylGene, Inc.
    Inventors: Moshe Szyf, Pascal Bigey, Shyam Ramchandani