Abstract: Alpha-tocopherol 4-aminobenzoate compounds, represented by formula (I), are prepared by the esterification of alpha-tocopherol with 4-aminobenzoic acid. The esters are converted into the element compounds in vivo, so that they have alpha-tocopherol's biological effect including antioxidation as well as the pharmaceutical and biological effects of 4-aminobenzoic acid, including the promotion of red blood cell formation and metabolism, the role of a growth stimulating factor, keeping the skin healthy, and the prevention of hair decoloration. In said formula (I) R1 and R2 which may be the same or different, each is a hydrogen atom or a linear or branched C1˜C4 alkyl chain.

Abstract: There is disclosed a method for producing acetylene alcohol compounds in a continuous process, which are produced via ethynylation in which ketones containing a group --CH.sub.2 COCH.sub.2 --, are condensed with acetylenes at a temperature of about 20 to 50.degree. C. under a pressure of about 10 to 30 kg/cm.sup.2 in the presence of a quaternary ammonium hydroxide anion exchange resin having strong basicity in an aprotic solvent by feeding a reactant mixture at an LHSV range of 0.1 to 5.0 and the reactant mixture comprises the acetylene, the ketone and the solvent at a molar ratio of 1.0:0.2-3.0:1.0-4.0.