Patents by Inventor Sian Eleri Roberts

Sian Eleri Roberts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin binding protein
    Patent number: 6884629
    Abstract: The present invention is directed to an immunoglobulin light chain binding protein which comprises the amino acid sequence of SEQ ID NO:1 modified by an amino acid substitution at one or more of positions 39, 53 and 57 and/or by an amino acid insertion between positions 59 and 60 such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin ?-chain is 400 nM or more at pH 8, or the amino acid sequence of a corresponding immunoglobulin light chain binding domain modified by an amino acid substitution at one or more of the positions equivalent to positions 39, 53 and 57 of SEQ ID NO:1 and/or by an amino acid insertion between positions equivalent to positions 59 and 60 of SEQ ID NO:1, such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin ?-chain is 400 nM or more at pH 8, or the amino acid sequence of a fragment of (a) or (b) which contains at least one said substitution and/or insertion, such that the dissociation constant (Kd) of the protei
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: April 26, 2005
    Assignee: Affitech AS
    Inventors: Michael Graham Gore, Jennifer Ann Beckingham, Sian Eleri Roberts
  • Immunoglobulin binding protein
    Publication number: 20020137918
    Abstract: The present invention is directed to an immunoglobulin light chain binding protein which comprises the amino acid sequence of SEQ ID NO:1 modified by an amino acid substitution at one or more of positions 39, 53 and 57 and/or by an amino acid insertion between positions 59 and 60 such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin &kgr;-chain is 400 nM or more at pH 8, or the amino acid sequence of a corresponding immunoglobulin light chain binding domain modified by an amino acid substitution at one or more of the positions equivalent to positions 39, 53 and 57 of SEQ ID NO:1 and/or by an amino acid insertion between positions equivalent to positions 59 and 60 of SEQ ID NO:1, such that the dissociation constant (Kd) of the protein with respect to human immunoglobulin &kgr;-chain is 400 nM or more at pH 8, or the amino acid sequence of a fragment of (a) or (b) which contains at least one said substitution and/or insertion, such that the dissociation constant (Kd) of th
    Type: Application
    Filed: March 13, 2001
    Publication date: September 26, 2002
    Inventors: Michael Graham Gore, Jennifer Ann Beckingham, Sian Eleri Roberts