Patents by Inventor Siao-Syun Guan

Siao-Syun Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dual-targeted carbonic anhydrase ix complex and contrast agent thereof
    Patent number: 11654203
    Abstract: Disclosed herein are a dual-targeted carbonic anhydrase IX complex, a contrast agent comprising the same, and a synthesizing method thereof. The dual-targeted carbonic anhydrase IX complex includes a carbonic anhydrase IX (CA9) binding peptide, a sulfonamide derivative, and a metal chelating agent. The dual-targeted carbonic anhydrase IX complex has potential for use as a molecular nuclear drug.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: May 23, 2023
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, R.O.C
    Inventors: Siao-Syun Guan, Tsai-Yueh Luo, Tse-Zung Liao, Cheng-Liang Peng, Kun-Liang Lin
  • DUAL-TARGETED CARBONIC ANHYDRASE IX COMPLEX AND CONTRAST AGENT THEREOF
    Publication number: 20210154334
    Abstract: Disclosed herein are a dual-targeted carbonic anhydrase IX complex, a contrast agent comprising the same, and a synthesizing method thereof. The dual-targeted carbonic anhydrase IX complex includes a carbonic anhydrase IX (CA9) binding peptide, a sulfonamide derivative, and a metal chelating agent. The dual-targeted carbonic anhydrase IX complex has potential for use as a molecular nuclear drug.
    Type: Application
    Filed: October 26, 2020
    Publication date: May 27, 2021
    Inventors: SIAO-SYUN GUAN, TSAI-YUEH LUO, TSE-ZUNG LIAO, CHENG-LIANG PENG, KUN-LIANG LIN
  • Method of colorectal cancer detection by using radiolabeled anti-GRP78 peptide
    Patent number: 8691189
    Abstract: The present disclosure describes techniques used for colorectal cancer detection. Position and distribution of colorectal cancer tumor are detected through nuclear imaging. Alternatively, stage of colorectal cancer is identified by shading value in tumor. Thus, the present disclosure provides a safe and noninvasive clinical method for diagnosing and tracing level and distribution of colorectal cancer before and after treatment.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: April 8, 2014
    Assignee: Institute of Nuclear Energy Research, Atomic Energy Council
    Inventors: Siao-Syun Guan, Chun-Chia Cheng, Shui-Cheng Lee, Hsien-Ming Wu
  • Method of Colorectal Cancer Detection by Using Radiolabeled Anti-GRP78 Peptide
    Publication number: 20120207675
    Abstract: The present disclosure describes techniques used for colorectal cancer detection. Position and distribution of colorectal cancer tumor are detected through nuclear imaging. Alternatively, stage of colorectal cancer is identified by shading value in tumor. Thus, the present disclosure provides a safe and noninvasive clinical method for diagnosing and tracing level and distribution of colorectal cancer before and after treatment.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 16, 2012
    Applicant: ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH
    Inventors: Siao-Syun Guan, Chun-Chia Cheng, Shui-Cheng Lee, Hsien-Ming Wu