Abstract: Methods of predicting bone or joint disease in a subject are disclosed. Methods of determining the effect of a candidate agent on any subject's risk of developing bone or joint disease are also disclosed. A method for generating a parameter map from a bone image of a subject includes obtaining the bone image of the subject, defining two or more regions of interest (ROIs) in the image, analyzing a plurality of positions in the ROIs to obtain measurements for one or more bone microarchitecture parameters and one or more bone macro-anatomy parameters, and generating the parameter map from the measurements.

Abstract: Methods of predicting bone or joint disease in a subject are disclosed. Methods of determining the effect of a candidate agent on any subject's risk of developing bone or joint disease are also disclosed. A method for generating a parameter map from a bone image of a subject includes obtaining the bone image of the subject, defining two or more regions of interest (ROIs) in the image, analyzing a plurality of positions in the ROIs to obtain measurements for one or more bone microarchitecture parameters and one or more bone macro-anatomy parameters, and generating the parameter map from the measurements.

Abstract: A method of predicting bone or articular disease in a subject includes determining one or more micro-structural parameters, one or more macroanatomical parameters or biomechanical parameters of a joint in the subject and combining at least two of the parameters to predict the risk of bone or articular disease.

Abstract: The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

Abstract: A method for providing digital video with data identifying motion, includes: recording digital video data during an action of an activity from an imager to a first memory within the camera as recorded digital video, wherein the camera is coupled to a person performing an action or to an object used by the person to perform the action; recording motion data from a movement sensor as the action is performed by a person or by an object used by the person during the activity along with the recorded digital video, wherein the movement sensor is coupled to the person performing the action or to the object used by the person to perform the action; automatically analyzing the motion data with a processor of the camera to detect a motion; adding a detected motion of the automatically analyzing as first metadata to the recorded digital video stored in the first memory; and validating the first metadata as motion of the activity.

Abstract: This disclosure relates to methods and devices for analyzing x-ray images. Futhermore, bone condition of a subject can be evaluated by analyzing x-ray images of the subject's bone and therapies can then be selected or devised for the subject.

Abstract: The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

Abstract: The present invention relates to methods and devices for evaluating bone conditions based on images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure from x-ray images.

Abstract: A method of predicting bone or articular disease in a subject includes determining one or more micro-structural parameters, one or more macroanatomical parameters or biomechanical parameters of a joint in the subject and combining at least two of the parameters to predict the risk of bone or articular disease.

Abstract: A method of predicting bone or articular disease in a subject includes determining one or more micro-structural parameters, one or more macroanatomical parameters or biomechanical parameters of a joint in the subject and combining at least two of the parameters to predict the risk of bone or articular disease.

Abstract: Methods of predicting fracture risk of a patient include: obtaining an image of a bone of the patient; determining one or more bone structure parameters; predicting a fracture line with the bone structure parameter; predicting a fracture load at which a fracture will happen; estimating body habitus of the patient; calculating a peak impact force on the bone when the patient falls; and predicting a fracture risk by calculating the ratio between the peak impact force and the fracture load. Inventive methods also include determining the effect of a candidate agent on any subject's risk of fracture.

Abstract: The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

Abstract: The present invention relates to methods and devices for evaluating bone conditions based on images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure from x-ray images.

Abstract: Methods of predicting bone or joint disease in a subject are disclosed. Methods of determining the effect of a candidate agent on any subject's risk of developing bone or joint disease are also disclosed. A method for generating a parameter map from a bone image of a subject includes obtaining the bone image of the subject, defining two or more regions of interest (ROIs) in the image, analyzing a plurality of positions in the ROIs to obtain measurements for one or more bone microarchitecture parameters and one or more bone macro-anatomy parameters, and generating the parameter map from the measurements.

Abstract: This invention is directed to methods of predicting bone or joint disease in a subject. The invention is also directed to methods of determining the effect of a candidate agent on any subject's risk of developing bone or joint disease.

Abstract: The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

Abstract: The present invention relates to methods and devices for evaluating bone conditions based on images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure from x-ray images.

Abstract: Methods of predicting fracture risk of a patient include: obtaining an image of a bone of the patient; determining one or more bone structure parameters; predicting a fracture line with the bone structure parameter; predicting a fracture load at which a fracture will happen; estimating body habitus of the patient; calculating a peak impact force on the bone when the patient falls; and predicting a fracture risk by calculating the ratio between the peak impact force and the fracture load. Inventive methods also include determining the effect of a candidate agent on any subject's risk of fracture.

Abstract: This disclosure relates to methods and devices for analyzing x-ray images. Furthermore, bone condition of a subject can be evaluated by analyzing x-ray images of the subject's bone from a sliding region of interest (ROI), e.g., an ROI that is moved on a pixel-by-pixel basis on the image, and therapies can then be selected or devised for the subject.

Abstract: Methods of predicting fracture risk of a patient include: obtaining an image of a bone of the patient; determining one or more bone structure parameters; predicting a fracture line with the bone structure parameter; predicting a fracture load at which a fracture will happen; estimating body habitus of the patient; calculating a peak impact force on the bone when the patient falls; and predicting a fracture risk by calculating the ratio between the peak impact force and the fracture load. Inventive methods also includes determining the effect of a candidate agent on any subject's risk of fracture.