Patents by Inventor Sibylle Berner

Sibylle Berner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A METHOD OF ASSESSING A FEMALE'S RISK OF HAVING PCOS AS WELL AS PRODUCTS AND USES RELATING THERETO
    Publication number: 20230221335
    Abstract: The present invention relates to a method of assessing a female’s risk of having polycystic ovary syndrome (PCOS), a kit for use in assessing a female’s risk of having PCOS, the use of a marker combination in the assessment of a female’s risk of having PCOS, a computer system for use in a method according to the present invention as well as a computer program and a computer-readable storage medium comprising instructions, which when executed by a computer, cause the computer to carry out the method of the present invention.
    Type: Application
    Filed: March 30, 2021
    Publication date: July 13, 2023
    Inventors: Sibylle Berner-Gatz, Martin Hund, Katharina Buck
  • Method for electrochemiluminescent labeling of nucleic acid, use in detection, and compositions therefor
    Patent number: 6027885
    Abstract: Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: February 22, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Cornelia Kruse-Mueller, Sibylle Berner, Cortina Kaletta
  • Modified phosphoramidite process for the production of modified nucleic acids
    Patent number: 5902878
    Abstract: The subject matter of the invention is a modified phosphoramidite process for the synthesis of nucleotide sequences. By use of a modified nucleoside phosphoramidite it is possible to produce nucleotide sequences which have a modified phosphate residue.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: May 11, 1999
    Assignee: Boehringer Mannheim GmbH
    Inventors: Heinz-Hartmut Seliger, Sibylle Berner, Klaus Muhlegger, Herbert Von Der Eltz, Hans-Georg Batz
  • Method for the sensitive detection of nucleic acids
    Patent number: 5753433
    Abstract: Method for the specific detection of nucleic acids in a sample by reaction of the sample with one or several labelled nucleotide triphosphates and one or several enzymes which catalyse the production of a labelled nucleic acid B which contains this nucleotide, non-thermally denaturation, reacting the sample with a nucleic acid probe C which is sufficiently complementary to nucleic acid B and which contains at least one immobilizable group, if desired, contacting the nucleic acid hybrid D formed with a solid phase which recognizes and binds the immobilizable group, removing the liquid from the solid phase and determining the label on the solid phase as a measure for the presence of the nucleic acid.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: May 19, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Christoph Kessler, Rudiger Ruger, Rudolf Seibl, Cornelia Kruse-Muller, Sibylle Berner
  • Modified phosphoramidite process for the production of modified nucleic acids
    Patent number: 5700919
    Abstract: The subject matter of the invention is a modified phosphoramidite process for the synthesis of nucleotide sequences. By use of a modified nucleoside phosphoramidite it is possible to produce nucleotide sequences which have a modified phosphate residue.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: December 23, 1997
    Assignee: Boehringer Mannhiem GmbH
    Inventors: Heinz-Hartmut Seliger, Sibylle Berner, Klaus Muhlegger, Herbert Von der Eltz, Hans-Georg Batz
  • Method for immobilizing nucleic acids using modified capture probes
    Patent number: 5639609
    Abstract: Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.
    Type: Grant
    Filed: June 9, 1994
    Date of Patent: June 17, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Cornelia Kruse-Mueller, Sibylle Berner, Cortina Kaletta