Patents by Inventor Sicco Hans POPMA

Sicco Hans POPMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES
    Publication number: 20240026350
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more nuclease recognition sequences upstream and downstream of a Gene editing multi-site that comprises a plurality of recognition sequences for a site-specific recombinase or a nuclease. The plurality of recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Application
    Filed: April 7, 2021
    Publication date: January 25, 2024
    Inventors: Sicco Hans POPMA, Di ZHANG
  • NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
    Publication number: 20210332356
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more nuclease recognition sequences upstream and downstream of a Gene editing multi-site that comprises a plurality of nuclease recognition sequences. The plurality of nuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Application
    Filed: February 25, 2021
    Publication date: October 28, 2021
    Inventors: Sicco Hans POPMA, Di ZHANG
  • NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
    Publication number: 20210093668
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more nuclease recognition sequences upstream and downstream of a Gene editing multi-site that comprises a plurality of nuclease recognition sequences. The plurality of nuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Application
    Filed: September 15, 2020
    Publication date: April 1, 2021
    Inventors: Sicco Hans Popma, Di Zhang
  • Nucleic acid constructs comprising gene editing multi-sites and uses thereof
    Patent number: 10828330
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more nuclease recognition sequences upstream and downstream of a Gene editing multi-site that comprises a plurality of nuclease recognition sequences. The plurality of nuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: November 10, 2020
    Assignee: IO Bioscience, Inc.
    Inventors: Sicco Hans Popma, Di Zhang
  • NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
    Publication number: 20190388470
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more nuclease recognition sequences upstream and downstream of a Gene editing multi-site that comprises a plurality of nuclease recognition sequences. The plurality of nuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Application
    Filed: March 25, 2019
    Publication date: December 26, 2019
    Inventors: Sicco Hans Popma, Di Zhang
  • NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
    Publication number: 20190381192
    Abstract: Disclosed herein is a polynucleotide construct comprising one or more primary endonuclease recognition sequences upstream and downstream of a multiple gene editing site that comprises a plurality of secondary endonuclease recognition sequences. The primary endonuclease recognition sequences facilitate insertion of the multiple gene editing site into a host cell genome. The secondary endonuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.
    Type: Application
    Filed: February 22, 2018
    Publication date: December 19, 2019
    Inventors: Sicco Hans POPMA, Di ZHANG