Patents by Inventor Siddarth Chandrasekaran

Siddarth Chandrasekaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240239914
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: October 20, 2023
    Publication date: July 18, 2024
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Publication number: 20240101696
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: March 17, 2023
    Publication date: March 28, 2024
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Patent number: 11827715
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: November 28, 2023
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Publication number: 20230181732
    Abstract: Provided herein are uses of antibodies that bind to CD163 expressed on a human myeloid cell in combination with checkpoint inhibitors. Among other things, these CD163 antibodies can be used with checkpoint inhibitors in methods of treatment of humans, such as methods of treating a cancer or methods of relieving T cell suppression.
    Type: Application
    Filed: September 2, 2022
    Publication date: June 15, 2023
    Inventors: Siddarth Chandrasekaran, Tyrel T. Smith, Kamal D. Puri, Randi M. Simmons, Peter Probst, Robert J. Lechleider
  • Patent number: 11634501
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: April 25, 2023
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Publication number: 20220289861
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: July 17, 2020
    Publication date: September 15, 2022
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Patent number: 11423456
    Abstract: In embodiments, methods and systems for order management and processing based on a distributed commerce platform are provided. A distributed commerce platform supports end-to-end integrated product publication, order-management and payment services. In particular, the distributed commerce platform supports components based on Application Programming Interfaces (API) that standardize the implementation of a distributed commerce solution or configuration of off-site buying experiences. Using the distributed commerce platform, merchants can concurrently offer, sell, and process orders for products through a plurality of different affiliate channels. The distributed commerce platform can also be implemented as a federated portal from which a merchant can identify affiliate channels to publish product objects, access the plurality of affiliate channels and define configurations for processing objects of the merchant's distributed commerce solution.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: August 23, 2022
    Assignee: STRIPE, INC.
    Inventors: Siddarth Chandrasekaran, John Brochan Collison, Cristina Joelle Cordova, James William Danz, Stanislas Vincent Francois Polu, Devesh Senapati
  • Publication number: 20210353763
    Abstract: Methods and compositions are described herein for covalently linking an antibody to a molecular payload. Compositions are described herein containing an antibody covalently linked to a molecular payload.
    Type: Application
    Filed: March 16, 2020
    Publication date: November 18, 2021
    Inventors: Diana LAC, Chun FENG, Gaurav BHARDWAJ, Siddarth CHANDRASEKARAN, Kit S. Lam
  • Publication number: 20210253733
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: April 22, 2021
    Publication date: August 19, 2021
    Inventors: Kamal D. PURI, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Patent number: 11034770
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: June 15, 2021
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Publication number: 20210047424
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: July 22, 2020
    Publication date: February 18, 2021
    Inventors: Kamal D. PURI, Siddarth CHANDRASEKARAN, Melissa L. CONERLY, Randi M. SIMMONS, Tyrel T. SMITH, Mark E. BRANUM, Peter PROBST
  • Patent number: 10867334
    Abstract: In embodiments, methods and systems for order management and processing based on a distributed commerce platform are provided. A distributed commerce platform supports end-to-end integrated product publication, order-management and payment services. In particular, the distributed commerce platform supports components based on Application Programming Interfaces (API) that standardize the implementation of a distributed commerce solution or configuration of off-site buying experiences. Using the distributed commerce platform, merchants can concurrently offer, sell, and process orders for products through a plurality of different affiliate channels. The distributed commerce platform can also be implemented as a federated portal from which a merchant can identify affiliate channels to publish product objects, access the plurality of affiliate channels and define configurations for processing objects of the merchant's distributed commerce solution.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: December 15, 2020
    Assignee: STRIPE, INC.
    Inventors: Siddarth Chandrasekaran, John Brochan Collison, Cristina Joelle Cordova, James William Danz, Stanislas Vincent Francois Polu, Devesh Senapati
  • Patent number: 10588982
    Abstract: Methods and compositions are described herein for covalently linking an antibody to a molecular payload. Compositions are described herein containing an antibody covalently linked to a molecular payload.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: March 17, 2020
    Assignee: The Regents of the University of California
    Inventors: Diana Lac, Chun Feng, Gaurav Bhardwaj, Siddarth Chandrasekaran, Kit S. Lam
  • Publication number: 20200009225
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Application
    Filed: August 23, 2019
    Publication date: January 9, 2020
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • Patent number: 10391146
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: August 27, 2019
    Assignee: Cornell University
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • Publication number: 20180140715
    Abstract: Methods and compositions are described herein for covalently linking an antibody to a molecular payload. Compositions are described herein containing an antibody covalently linked to a molecular payload.
    Type: Application
    Filed: October 6, 2017
    Publication date: May 24, 2018
    Inventors: Diana LAC, Chun FENG, Gaurav BHARDWAJ, Siddarth CHANDRASEKARAN, Kit S. LAM
  • Publication number: 20170046759
    Abstract: In embodiments, methods and systems for order management and processing based on a distributed commerce platform are provided. A distributed commerce platform supports end-to-end integrated product publication, order-management and payment services. In particular, the distributed commerce platform supports components based on Application Programming Interfaces (API) that standardize the implementation of a distributed commerce solution or configuration of off-site buying experiences. Using the distributed commerce platform, merchants can concurrently offer, sell, and process orders for products through a plurality of different affiliate channels. The distributed commerce platform can also be implemented as a federated portal from which a merchant can identify affiliate channels to publish product objects, access the plurality of affiliate channels and define configurations for processing objects of the merchant's distributed commerce solution.
    Type: Application
    Filed: August 12, 2015
    Publication date: February 16, 2017
    Inventors: SIDDARTH CHANDRASEKARAN, JOHN BROCHAN COLLISON, CRISTINA JOELLE CORDOVA, JAMES WILLIAM DANZ, STANISLAS VINCENT FRANCOIS POLU, DEVESH SENAPATI
  • Publication number: 20160184395
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 30, 2016
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • Publication number: 20150072662
    Abstract: The disclosure is directed to systems and methods for switching a data downloading session from a first mobile device to a second mobile device. The data downloading session first commences on the first mobile device. During the session, a download transfer condition is identified. In response, the first mobile device sends the second mobile device download resumption information, which is specifically adapted to enable the second mobile device to continue the data downloading session without having to restart an interrupted downloading operation.
    Type: Application
    Filed: September 9, 2013
    Publication date: March 12, 2015
    Applicant: NVIDIA Corporation
    Inventors: Siddarth Chandrasekaran, Rameez Syed, Mahesh Meena
  • Patent number: 8753880
    Abstract: A method of enriching stem or progenitor cells that includes growing a heterogeneous cell sample comprising stem and/or progenitor cells on a first substrate that is hydrophobic and has an elastic modulus less than about 100 MPa; recovering the heterogeneous cell sample from the first substrate; growing the recovered heterogeneous cell sample on a second substrate that is hydrophilic and has an elastic modulus higher than the elastic modulus of the first substrate to produce a subpopulation of nonadherent cells and a subpopulation of adherent cells; and recovering the nonadherent cell subpopulation, which is enriched for stem and/or progenitor cells.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: June 17, 2014
    Assignee: University of Rochester
    Inventors: Lisa DeLouise, Siddarth Chandrasekaran