Patents by Inventor Siddharth Narendran

Siddharth Narendran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING OCULAR DISORDERS
    Publication number: 20230355553
    Abstract: Provided are methods for treating macular degeneration, optionally macular degeneration, in subject in need thereof. In some embodiments, the methods include administering to a subject in need thereof a therapeutically effective amount of fluoxetine in an amount and via a route sufficient to treat or prevent development of macular degeneration in the subjects. Also provided are methods for inhibiting activation of an NLRP3-ASC inflammasome in the subjects, inhibiting ASC speck formation in the subjects, inhibiting Alu RNA-induced RPE degeneration in the subjects, and treatment and/or prevention of the development of diseases, disorders, and/ or conditions.
    Type: Application
    Filed: February 11, 2021
    Publication date: November 9, 2023
    Applicant: University of Virginia Patent Foundation
    Inventors: Jayakrishna Ambati, Ivana Apicella, Meenakshi Ambati, Siddharth Narendran, Bradley David Unti Gelfand, Shao-bin Wang, Felipe Pereira
  • DRUG VEHICLE COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20230285286
    Abstract: The invention is directed to topical drug vehicle platform compositions for ophthalmological and dermatological use. These compositions are capable of solubilizing active ingredients having a logP value of more than about 3.0 and/or having a solubility in deionized water of about 33,000 parts per million or less at 25° C.
    Type: Application
    Filed: January 23, 2023
    Publication date: September 14, 2023
    Inventors: Gerald Horn, Siddharth Narendran, Venkat Goskonda