Abstract: Systems and methods are described herein for routing data by transferring a physical storage device for at least part of a route between source and destination locations. In one example, a computing resource service provider, may receive a request to transfer data from a customer center to a data center. The service provider may determine a route, which includes one or more of a physical path or a network path, for the data loaded onto a physical storage device to reach the data center from the customer center. Determining the route may include associating respective cost values to individual physical and network paths between physical stations between the customer and end data centers, and selecting one or more of the paths to reduce a total cost of the route. Route information may then be associated with the physical storage device based on the route.

Abstract: A system is described herein. The system includes an agent and a transmitter. The agent is to a capture room specific data signals from peripheral devices within a conference room, operating system data signals, and application data signals, wherein the application data signals are obtained from a conferencing service application and wherein the agent is to package the room specific data signals, the operating system data signals, and the application data signals with system metadata into room health data. The transmitter is to transmit the room health data to a management cloud via a communications broker.

Abstract: A device-implemented method for providing managed services is described herein. An example method includes determining each managed device of a plurality of managed devices available in a shared space, and determining health data for the shared space. The health data describes properties of each managed device of the plurality of managed devices, including update information, performance information, configuration information, and security information. The method further includes identifying a problem with at least one of the plurality of managed devices, the problem being identifiable based on analysis of the health data for the shared space. The method also includes coordinating operational maintenance for the at least one of the plurality of managed devices to alleviate the problem. Coordinating operational maintenance may include performing at least two of a software update, a configuration change, and uninstalling software.

Abstract: A system is described herein. The system includes an agent and a transmitter. The agent is to a capture room specific data signals from peripheral devices within a conference room, operating system data signals, and application data signals, wherein the application data signals are obtained from a conferencing service application and wherein the agent is to package the room specific data signals, the operating system data signals, and the application data signals with system metadata into room health data. The transmitter is to transmit the room health data to a management cloud via a communications broker.

Abstract: The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.

Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.

Abstract: The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.

Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.

Abstract: Systems and methods for mapping identifiers are provided. Activity logs illustrate activities and/or events associated with a plurality of identifiers. The identifiers may be registered identifiers, unregistered identifiers, or a combination thereof. When at least two identifiers share a linking attribute, the at least two identifiers may be mapped to one another, along with information associated therewith (if any) such as a user profile. Each subsequent line of an activity line may also be mapped to the identifiers of the initial single line when a linking attribute or an overlapping identifier is present. A number of identifiers associated with each other may be increased by mapping identifiers and, thus, a targeted audience for a customized advertisement may, in turn, be increased.

Abstract: Methods and systems for maintaining user privacy preferences based on one or more user identifications across a plurality of applications are provided. Two or more user identifications are received with associated user privacy preferences. The received user identification is compared against other user identifications to determine if the user identifications relate to the same user. It may be determined that two user identifications are related if they have at least one browser property in common. A consolidated data stream of the user privacy preferences for the related user identifications is created. The consolidated data stream is communicated to one or more applications and propagated to maintain the user privacy preferences across the applications relating to the user identification.

Abstract: The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.

Abstract: Systems and methods for providing effective and targeted advertisements to consumers through the generations and use of personas and family identities. A persona relates to a user and a contextual environment associated with the user. The personas allow advertisers to provide advertisements related to the contextual environment of a persona. A family identity relates to a set of users associated with at least one device. The family identities allow advertisers to provide advertisements applicable to a set of users.

Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.

Abstract: Large sets of unorganized data may provide little value in identifying useful observations from such data. For example, an online merchant may maintain a database of millions of user IDs (e.g., a cookie ID, a login ID, a device ID, a network ID, etc.) along with content viewed and/or actions taken with the user IDs, where minimal associations are known between user IDs. It may be advantageous to link together user IDs of respective users to capture a comprehensive view of respective users' activities. Accordingly, one or more systems and/or techniques for identifying a cluster of nodes based upon transforming a set of node pairings (e.g., pairings of related nodes) one or more times are disclosed herein. Iterative transformations may be performed until respective nodes are paired with merely their smallest neighboring node and are paired with no other node. In this way, node clusters may be identifiable.

Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.

Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.

Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.

Abstract: The present invention relates to compounds of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.

Abstract: Systems and methods for controlling the work load on a distributed system comprising a plurality of stages are provided. The capacity of a present stage is monitored, using either various resources of the present stage or rates of work completion and work receipt of the present stage. Information indicating the capacity of a succeeding stage are obtained and communicated to the present stage. The monitored capacity information of the present stage and the communicated information of the succeeding stage, either alone or in combination, are used to determine if a throttling action is necessary to control the load of work at the present stage. A provided throttling technique inserts an appropriate delay before the present stage to allow the present stage to process an amount of work without saturating the capacity of the present stage. This technique is applied at each stage of the distributed system to control the work load of the overall system by controlling the work load at each stage.

Abstract: Large sets of unorganized data may provide little value in identifying useful observations from such data. For example, an online merchant may maintain a database of millions of user IDs (e.g., a cookie ID, a login ID, a device ID, a network ID, etc.) along with content viewed and/or actions taken with the user IDs, where minimal associations are known between user IDs. It may be advantageous to link together user IDs of respective users to capture a comprehensive view of respective users' activities. Accordingly, one or more systems and/or techniques for identifying a cluster of nodes based upon transforming a set of node pairings (e.g., pairings of related nodes) one or more times are disclosed herein. Iterative transformations may be performed until respective nodes are paired with merely their smallest neighboring node and are paired with no other node. In this way, node clusters may be identifiable.