Patents by Inventor Siddharthan CHANDRAN

Siddharthan CHANDRAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCED MITOCHONDRIAL RESPONSE WITH THIOZOLIDINEDIONE, PIOGLITAZONE OR ROSIGLITAZONE
    Publication number: 20230263787
    Abstract: There is provided a method of targeting mitochondrial biogenesis and mitochondrial transport from the cell body to axon to protect acutely demyelinated axons from degeneration. The method may comprise increasing mobilization of mitochondria from the neuronal cell body to the demyelinated axon to treat demyelinating disorders and provide a novel neuroprotective strategy for vulnerable acutely demyelinated axons. The method may comprise mitochondrial biogenesis in the demyelinated axon to treat demyelinating disorders and provide a novel neuroprotective strategy for vulnerable acutely demyelinated axons. The method comprises a variety of compounds and strategies for increasing mitochondrial transport and biogenesis to the demyelinated axon in both the peripheral and central nervous systems.
    Type: Application
    Filed: June 14, 2021
    Publication date: August 24, 2023
    Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH
    Inventors: Simon LICHT-MAYER, Don MAHAD, Graham CAMPBELL, Siddharthan CHANDRAN