Patents by Inventor Siddiqui Jaweed Mukarram

Siddiqui Jaweed Mukarram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of (+)-(S)-clopidogrel bisulfate form-1
    Patent number: 7482453
    Abstract: The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-?-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: January 27, 2009
    Assignee: Wockhardt Ltd.
    Inventors: Mohammed Siddiqui Jaweed Mukarram, Yekanathsa Aravind Merwade, Reyaz Anjum Khan
  • Process for the manufacture of (+)-(s)-clopidogrel bisulfate form-1
    Patent number: 7291735
    Abstract: The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-?-(2-chlorophenyl)-6,7-dihydrothieno [3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: November 6, 2007
    Inventors: Mohammed Siddiqui Jaweed Mukarram, Yekanathsa Aravind Merwade, Reyaz Anjum Khan
  • Method for preparing Ziprasidone monohydrochloride-hydrate
    Publication number: 20070078143
    Abstract: Ziprasidone is a known agent for treating various disorders including schizophrenia, migraine pain and anxiety. The present invention provides a method for preparing 5-(2-(4-1,2-benzisothiazol-3-yl)piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one (Ziprasidone) monohydrochloride-hydrate or a pharmaceutically acceptable acid addition salt thereof.
    Type: Application
    Filed: May 26, 2006
    Publication date: April 5, 2007
    Inventors: Siddiqui Jaweed Mukarram, Aravind Merwade, Kumar Singh, Pawan Solanki
  • Process for the production of cefotaxime sodium
    Publication number: 20070004916
    Abstract: A process for the production of 7-[2-(2-amino-4-thiazolyl)-2-syn-methoxyimino-acetamido]-3-acetoxymethyl-3-cephem-4-carboxylic acid (Cefotaxime) in aqueous isopropyl alcohol is provided. The synthesis provides the product in greater than 99 % HPLC purity.
    Type: Application
    Filed: July 17, 2006
    Publication date: January 4, 2007
    Inventors: Siddiqui Jaweed Mukarram, Rashid Khan, Ram Yadav, Mohammed Khan
  • Efficient method for the manufacture of (E) -Entacapone polymorphic Form A
    Publication number: 20070004935
    Abstract: The present invention describes an improved method for the preparation of Entacapone, (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide, polymorphic Form A, which is an inhibitor of catechol-O-methyltransferase (COMT) enzyme. The method provides pure (E)-isomer of Entacapone Form A.
    Type: Application
    Filed: June 26, 2006
    Publication date: January 4, 2007
    Inventors: Siddiqui Jaweed Mukarram, Rashid Khan, Ram Yadav
  • Process for the manufacture of citalopram hydrobromide
    Publication number: 20060293530
    Abstract: The present invention describes an improved process for the preparation of pure 1-(4?-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-phthalanecarbonitrile and its bromide salt (citalopram hydrobromide), which is a well known antidepressant. Another aspect of the invention is isolation of crystalline (4-Bromo-2-hydroxymethyl)phenyl-(4-fluorophenyl)-3-(dimethylaminopropyl)methanol (Bromodiol) and conversion of desmethylcitalopram which is formed during the cyanide exchange reaction, to citalopram by heating with a mixture of formaldehyde and formic acid in chloroform. The resulting citalopram is purified using conventionally extraction methodology.
    Type: Application
    Filed: April 28, 2006
    Publication date: December 28, 2006
    Applicant: Wockhardt Ltd.
    Inventors: Siddiqui Jaweed Mukarram, Bhargav Upadhye, Krishna Mishra, Mohammed Farooqui
  • Process for the manufacture of 1,2-benzisoxazole-3-methanesulphonamide
    Publication number: 20060287535
    Abstract: The present invention provides an improved process for the preparation of 1,2-Benzisoxazole-3-methanesulphonamide (Zonisamide), an anti-epileptic agent having anti-convulsant and anti-neurotoxic effects. In another aspect, the invention provides a key intermediate, 1,2-benzisoxazole-3-methane sodium sulfonate (BOS-Na:NaCl), isolated as a crystalline sodium chloride associated compound. The BOS-Na:NaCl isolated is directly converted to Zonisamide using a controlled molar ratio of chlorosulfonic acid to avoid conversion to the disulfonated side products.
    Type: Application
    Filed: May 11, 2006
    Publication date: December 21, 2006
    Inventors: Siddiqui Jaweed Mukarram, Aravind Merwade, Jagdish Shukla, Anis Saiyad