Abstract: There are described compounds of formula I, ##STR1## in which Ar.sub.1 and Ar.sub.2, which may be the same or different, each independently represent phenyl or pyridinyl, the phenyl or the pyridinyl each optionally being substituted by one or more of halogen; hydroxy; --COOR.sub.12 ; trihalomethyl; alkoxy C1 to 6; alkyl C1 to 6; --NR.sub.1 R.sub.2 ; alkoxy C1 to 6 substituted by --NR.sub.1 R.sub.2 or by phenyl; or alkyl C1 to 6 substituted by --NR.sub.1 R.sub.2 or by --COOR.sub.12 ;R.sub.1 and R.sub.2, which may be the same or different, each independently represent hydrogen or alkyl C1 to 6,R.sub.3 represents hydrogen, alkyl C1 to 6, alkanoyl C1 to 6, benzoyl, --COOR.sub.8, or --CONHR.sub.11,R.sub.4, R.sub.5, R.sub.6 and R.sub.7, which may be the same or different each independently represent hydrogen, alkyl C1 to 6 or phenyl;R.sub.8 represents alkyl C1 to 6 or aryl,R.sub.11 represents alkyl C1 to 6 or aryl,R.sub.12 represents hydrogen or alkyl C1 to 6, and pharmaceutically acceptable derivatives thereof.

Abstract: There are described compounds of formula I, ##STR1## in which Ar.sub.1 and Ar.sub.2, which may be the same or different, each independently represent phenyl or pyridinyl, the phenyl or the pyridinyl each optionally being substituted by one or more of halogen; hydroxy; --COOR.sub.12 ; trihalomethyl; alkoxy C1 to 6; alkyl C1 to 6; --NR.sub.1 R.sub.2 ; alkoxy C1 to 6 substituted by --NR.sub.1 R.sub.2 or by phenyl; or alkyl C1 to 6 substituted by --NR.sub.1 R.sub.2 or by --COOR.sub.12 ;R.sub.1 and R.sub.2, which may be the same or different, each independently represent hydrogen or alkyl C1 to 6,R.sub.3 represents hydrogen, alkyl C1 to 6, alkanoyl C1 to 6, benzoyl, --COOR.sub.8, or --CONHR.sub.11,R.sub.4, R.sub.5, R.sub.6 and R.sub.7, which may be the same or different each independently represent hydrogen, alkyl C1 to 6 or phenyl,R.sub.8 represents alkyl C1 to 6 or aryl,R.sub.11 represents alkyl C1 to 6 or aryl,R.sub.12 represents hydrogen or alkyl C1 to 6, and pharmaceutically acceptable derivatives thereof.

Abstract: There are described compounds of formula I, ##STR1## in which either R.sub.2 represents hydrogen, alkyl or Ar.sub.2, andR.sub.3 represents hydrogen, alkyl or alkyl substituted by Ar.sub.3 ;or R.sub.2 and R.sub.3 together form the chain --(CH.sub.2).sub.m --;R.sub.4 and R.sub.5, which may be the same or different, each independently represent hydrogen, halogen, Ar, alkyl, or alkyl substituted by Ar,Ar.sub.1, Ar.sub.2 and Ar, which may be the same or different each independently represent aryl or aryl substituted by one or more ofhalogen, hydroxy, --CN, --COR.sub.6, trihalomethyl, alkoxy, alkoxy substituted by --COR.sub.6, alkoxy substituted by --NR.sub.7 R.sub.8, alkyl, alkyl substituted by --COR.sub.6, alkyl substituted by NR.sub.7 R.sub.8, alkoxy substituted by Ar.sub.3, S(O).sub.n R.sub.9, --NR.sub.7 R.sub.8 or OAr.sub.3 ;R.sub.6 represents --OR.sub.10, --NR.sub.7 R.sub.8, hydrogen or alkyl;R.sub.7 and R.sub.8, which may be the same or different, each independently represent hydrogen, alkyl, alkanoyl or Ar.

Abstract: There are described compounds of formula I, ##STR1## in which R.sub.1 represents hydrogen, alkyl, alkanoyl or alkyl substituted by Ar.sub.1,R.sub.3, R.sub.4 and R.sub.5, which may be the same or different, each independently represent hydrogen, alkyl or Ar.sub.3,Ar.sub.1, Ar.sub.2 and Ar.sub.3, which may be the same or different, independently represent phenyl or phenyl substituted by one or more of alkyl, hydroxy, alkoxy, NR.sub.6 R.sub.7 or halogen,R.sub.6 and R.sub.7, which may be the same or different, independently represent hydrogen or alkyl,and pharmaceutically acceptable acid addition salts thereof.Compositions containing the compounds and methods for their preparation are also described.The compounds are indicated for use as pharmaceutical, e.g. anti-inflammatory, agents.