Patents by Inventor Sidney Wolfe

Sidney Wolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized interferon compositions
    Publication number: 20060008447
    Abstract: Stabilized pharmaceutical formulations comprising IFN-? and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-? adducts in comparison with IFN-? formulated with mannitol that has not been highly purified. Methods for increasing the stability of IFN-? or a variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.
    Type: Application
    Filed: July 22, 2005
    Publication date: January 12, 2006
    Applicant: Chiron Corporation
    Inventors: Sidney Wolfe, Maninder Hora
  • Compositions and methods for stabilizing biological molecules upon lyophilization
    Publication number: 20030124139
    Abstract: The present invention is directed to compositions and methods for the preparation of biological molecules, in particular MenC-CRM 197. Biological molecules dissolved in dissolution buffers comprising at least one amorphous excipient and an amorphous buffer exhibit reduced aggregation and proteolytic breakdown.
    Type: Application
    Filed: November 20, 2002
    Publication date: July 3, 2003
    Inventors: Irina Esikova, Sidney Wolfe, James Thomson, Maninder Hora